6UO9

Human metabotropic GABA(B) receptor bound to agonist SKF97541 in its intermediate state 2

Summary for 6UO9

Entry DOI	10.2210/pdb6uo9/pdb
EMDB information	20823
Descriptor	Gamma-aminobutyric acid type B receptor subunit 1, Gamma-aminobutyric acid type B receptor subunit 2, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
Functional Keywords	g protein-coupled receptor, gaba, gabab, neurotransmitter, membrane protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	2
Total formula weight	177515.50
Authors	Shaye, H.,Han, G.W.,Gati, C.,Cherezov, V. (deposition date: 2019-10-14, release date: 2020-06-10, Last modification date: 2020-08-26)
Primary citation	Shaye, H.,Ishchenko, A.,Lam, J.H.,Han, G.W.,Xue, L.,Rondard, P.,Pin, J.P.,Katritch, V.,Gati, C.,Cherezov, V. Structural basis of the activation of a metabotropic GABA receptor. Nature, 584:298-303, 2020 Cited by PubMed: 32555460 DOI: 10.1038/s41586-020-2408-4 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (4.8 Å)

Structure validation