4AH2
 
 | | HLA-DR1 with covalently linked CLIP106-120 in canonical orientation | | 分子名称: | GLYCEROL, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN,DRB1-1 BETA CHAIN, ... | | 著者 | Schlundt, A, Guenther, S, Sticht, J, Wieczorek, M, Roske, Y, Heinemann, U, Freund, C. | | 登録日 | 2012-02-03 | | 公開日 | 2012-08-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | | 主引用文献 | Peptide Linkage to the Alpha-Subunit of Mhcii Creates a Stably Inverted Antigen Presentation Complex.
J.Mol.Biol., 423, 2012
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4AEN
 | | HLA-DR1 with covalently linked CLIP106-120 in reversed orientation | | 分子名称: | GLYCEROL, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN GAMMA CHAIN, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, ... | | 著者 | Schlundt, A, Guenther, S, Sticht, J, Wieczorek, M, Roske, Y, Heinemann, U, Freund, C. | | 登録日 | 2012-01-11 | | 公開日 | 2012-08-01 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Peptide Linkage to the Alpha-Subunit of Mhcii Creates a Stably Inverted Antigen Presentation Complex.
J.Mol.Biol., 423, 2012
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8RHS
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5JU7
 | | DNA BINDING DOMAIN OF E.COLI CADC | | 分子名称: | Transcriptional activator CadC, ZINC ION | | 著者 | Janowski, R, Schlundt, A, Sattler, M, Niessing, D. | | 登録日 | 2016-05-10 | | 公開日 | 2017-04-26 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure-function analysis of the DNA-binding domain of a transmembrane transcriptional activator.
Sci Rep, 7, 2017
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4QI2
 | | X-ray structure of the ROQ domain from murine Roquin-1 in complex with a 23-mer Tnf-CDE RNA | | 分子名称: | RNA (5'-R(*AP*CP*AP*UP*GP*UP*UP*UP*UP*CP*UP*GP*UP*GP*AP*AP*AP*AP*CP*GP*GP*AP*G)-3'), Roquin-1 | | 著者 | Janowski, R, Schlundt, A, Sattler, M, Niessing, D. | | 登録日 | 2014-05-30 | | 公開日 | 2014-07-16 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation.
Nat.Struct.Mol.Biol., 21, 2014
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4QI0
 | | X-ray structure of the ROQ domain from murine Roquin-1 | | 分子名称: | 1,2-ETHANEDIOL, Roquin-1 | | 著者 | Janowski, R, Schlundt, A, Sattler, M, Niessing, D. | | 登録日 | 2014-05-30 | | 公開日 | 2014-07-16 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Structural basis for RNA recognition in roquin-mediated post-transcriptional gene regulation.
Nat.Struct.Mol.Biol., 21, 2014
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6GQE
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6TQB
 | | X-ray structure of Roquin ROQ domain in complex with a UCP3 CDE1 SL RNA motif | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, MAGNESIUM ION, ... | | 著者 | Binas, O, Tants, J.-N, Peter, S.A, Janowski, R, Davydova, E, Braun, J, Niessing, D, Schwalbe, H, Weigand, J.E, Schlundt, A. | | 登録日 | 2019-12-16 | | 公開日 | 2020-05-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural basis for the recognition of transiently structured AU-rich elements by Roquin.
Nucleic Acids Res., 48, 2020
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5F5F
 | | X-ray structure of Roquin ROQ domain in complex with a Selex-derived hexa-loop RNA motif | | 分子名称: | RNA (5'-R(P*UP*GP*AP*CP*UP*GP*CP*GP*UP*UP*UP*UP*AP*GP*GP*AP*GP*UP*UP*A)-3'), Roquin-1 | | 著者 | Janowski, R, Schlundt, A, Sattler, M, Niessing, D. | | 登録日 | 2015-12-04 | | 公開日 | 2016-04-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Roquin recognizes a non-canonical hexaloop structure in the 3'-UTR of Ox40.
Nat Commun, 7, 2016
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5F5H
 | | X-ray structure of Roquin ROQ domain in complex with Ox40 hexa-loop RNA motif | | 分子名称: | GLYCEROL, RNA (5'-R(P*CP*CP*AP*CP*AP*CP*CP*GP*UP*UP*CP*UP*AP*GP*GP*UP*GP*CP*UP*GP*G)-3'), Roquin-1 | | 著者 | Janowski, R, Schlundt, A, Sattler, M, Niessing, D. | | 登録日 | 2015-12-04 | | 公開日 | 2016-04-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.23 Å) | | 主引用文献 | Roquin recognizes a non-canonical hexaloop structure in the 3'-UTR of Ox40.
Nat Commun, 7, 2016
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6TQA
 | | X-ray structure of Roquin ROQ domain in complex with a UCP3 CDE2 SL RNA motif | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, RNA (5'-R(P*GP*GP*UP*GP*CP*CP*UP*AP*AP*UP*AP*UP*UP*UP*AP*GP*GP*CP*AP*CP*(CCC))-3'), ... | | 著者 | Binas, O, Tants, J.-N, Peter, S.A, Janowski, R, Davydova, E, Braun, J, Niessing, D, Schwalbe, H, Weigand, J.E, Schlundt, A. | | 登録日 | 2019-12-16 | | 公開日 | 2020-05-27 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis for the recognition of transiently structured AU-rich elements by Roquin.
Nucleic Acids Res., 48, 2020
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3PDO
 | | Crystal Structure of HLA-DR1 with CLIP102-120 | | 分子名称: | FORMIC ACID, GLYCEROL, HLA class II histocompatibility antigen gamma chain, ... | | 著者 | Gunther, S, Schlundt, A, Sticht, J, Roske, Y, Heinemann, U, Wiesmuller, K.-H, Jung, G, Falk, K, Rotzschke, O, Freund, C. | | 登録日 | 2010-10-23 | | 公開日 | 2010-12-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Bidirectional binding of invariant chain peptides to an MHC class II molecule.
Proc.Natl.Acad.Sci.USA, 107, 2010
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3PGC
 | | Crystal Structure of HLA-DR1 with CLIP106-120, flipped peptide orientation | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, HLA class II histocompatibility antigen gamma chain, ... | | 著者 | Gunther, S, Schlundt, A, Sticht, J, Roske, Y, Heinemann, U, Wiesmuller, K.-H, Jung, G, Falk, K, Rotzschke, O, Freund, C. | | 登録日 | 2010-11-01 | | 公開日 | 2010-12-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.66 Å) | | 主引用文献 | Bidirectional binding of invariant chain peptides to an MHC class II molecule.
Proc.Natl.Acad.Sci.USA, 107, 2010
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3PGD
 | | Crystal Structure of HLA-DR1 with CLIP106-120, canonical peptide orientation | | 分子名称: | HLA class II histocompatibility antigen gamma chain, HLA class II histocompatibility antigen, DR alpha chain, ... | | 著者 | Gunther, S, Schlundt, A, Sticht, J, Roske, Y, Heinemann, U, Wiesmuller, K.-H, Jung, G, Falk, K, Rotzschke, O, Freund, C. | | 登録日 | 2010-11-01 | | 公開日 | 2010-12-08 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | | 主引用文献 | Bidirectional binding of invariant chain peptides to an MHC class II molecule.
Proc.Natl.Acad.Sci.USA, 107, 2010
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6RO1
 | | X-ray crystal structure of the MTR4 NVL complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, Exosome RNA helicase MTR4, ... | | 著者 | Lingaraju, M, Langer, L.M, Basquin, J, Falk, S, Conti, E. | | 登録日 | 2019-05-10 | | 公開日 | 2019-07-03 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | | 主引用文献 | The MTR4 helicase recruits nuclear adaptors of the human RNA exosome using distinct arch-interacting motifs.
Nat Commun, 10, 2019
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5M0H
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5M0I
 | | Crystal structure of the nuclear complex with She2p and the ASH1 mRNA E3-localization element | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, ASH1-E3 element, ... | | 著者 | Edelmann, F.T, Janowski, R, Niessing, D. | | 登録日 | 2016-10-05 | | 公開日 | 2017-01-18 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Molecular architecture and dynamics of ASH1 mRNA recognition by its mRNA-transport complex.
Nat. Struct. Mol. Biol., 24, 2017
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5M0J
 | | Crystal structure of the cytoplasmic complex with She2p, She3p, and the ASH1 mRNA E3-localization element | | 分子名称: | ASH1 E3 (28 nt-loop), MAGNESIUM ION, SWI5-dependent HO expression protein 2,SWI5-dependent HO expression protein 3 | | 著者 | Edelmann, F.T, Janowski, R, Niessing, D. | | 登録日 | 2016-10-05 | | 公開日 | 2017-01-18 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Molecular architecture and dynamics of ASH1 mRNA recognition by its mRNA-transport complex.
Nat. Struct. Mol. Biol., 24, 2017
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6XXB
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6XWJ
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6XXA
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6XWW
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6GD2
 | | Structure of HuR RRM3 in complex with RNA | | 分子名称: | ELAV-like protein 1, RNA (5'-R(P*UP*UP*UP*AP*UP*UP*U)-3') | | 著者 | Pabis, M, Sattler, M. | | 登録日 | 2018-04-21 | | 公開日 | 2018-10-31 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | HuR biological function involves RRM3-mediated dimerization and RNA binding by all three RRMs.
Nucleic Acids Res., 47, 2019
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6GD3
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6G2K
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