6TQA

X-ray structure of Roquin ROQ domain in complex with a UCP3 CDE2 SL RNA motif

Summary for 6TQA

• Entry DOI: 10.2210/pdb6tqa/pdb
• Descriptor: Roquin-1, RNA (5'-R(P*GP*GP*UP*GP*CP*CP*UP*AP*AP*UP*AP*UP*UP*UP*AP*GP*GP*CP*AP*CP*(CCC))-3'), CHLORIDE ION, ... (5 entities in total)
• Functional Keywords: roquin, roq domain, rna binding, cde2, rna binding protein
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 8
• Total formula weight: 109252.78

Authors

Binas, O.,Tants, J.-N.,Peter, S.A.,Janowski, R.,Davydova, E.,Braun, J.,Niessing, D.,Schwalbe, H.,Weigand, J.E.,Schlundt, A. (deposition date: 2019-12-16, release date: 2020-05-27, Last modification date: 2024-01-24)

• Primary citation: Binas, O.,Tants, J.N.,Peter, S.A.,Janowski, R.,Davydova, E.,Braun, J.,Niessing, D.,Schwalbe, H.,Weigand, J.E.,Schlundt, A.; Structural basis for the recognition of transiently structured AU-rich elements by Roquin.; Nucleic Acids Res., 48:7385-7403, 2020; PubMed: 32491174; DOI: 10.1093/nar/gkaa465

Experimental method

X-RAY DIFFRACTION (2.4 Å)