6TQA
X-ray structure of Roquin ROQ domain in complex with a UCP3 CDE2 SL RNA motif
Summary for 6TQA
Entry DOI | 10.2210/pdb6tqa/pdb |
Descriptor | Roquin-1, RNA (5'-R(P*GP*GP*UP*GP*CP*CP*UP*AP*AP*UP*AP*UP*UP*UP*AP*GP*GP*CP*AP*CP*(CCC))-3'), CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | roquin, roq domain, rna binding, cde2, rna binding protein |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 8 |
Total formula weight | 109252.78 |
Authors | Binas, O.,Tants, J.-N.,Peter, S.A.,Janowski, R.,Davydova, E.,Braun, J.,Niessing, D.,Schwalbe, H.,Weigand, J.E.,Schlundt, A. (deposition date: 2019-12-16, release date: 2020-05-27, Last modification date: 2024-01-24) |
Primary citation | Binas, O.,Tants, J.N.,Peter, S.A.,Janowski, R.,Davydova, E.,Braun, J.,Niessing, D.,Schwalbe, H.,Weigand, J.E.,Schlundt, A. Structural basis for the recognition of transiently structured AU-rich elements by Roquin. Nucleic Acids Res., 48:7385-7403, 2020 Cited by PubMed: 32491174DOI: 10.1093/nar/gkaa465 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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