3D9W
 
 | | Crystal Structure Analysis of Nocardia farcinica Arylamine N-acetyltransferase | | 分子名称: | Putative acetyltransferase | | 著者 | Li de la Sierra-Gallay, I, Pluvinage, B, Rodrigues-Lima, F, Martins, M, Dupret, J.M. | | 登録日 | 2008-05-28 | | 公開日 | 2008-09-02 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Functional and structural characterization of the arylamine N-acetyltransferase from the opportunistic pathogen Nocardia farcinica
J.Mol.Biol., 383, 2008
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3LNB
 | | Crystal Structure Analysis of Arylamine N-acetyltransferase C from Bacillus anthracis | | 分子名称: | COENZYME A, FORMIC ACID, N-acetyltransferase family protein | | 著者 | Li de la Sierra-Gallay, I, Pluvinage, B, Rodrigues-Lima, F. | | 登録日 | 2010-02-02 | | 公開日 | 2011-01-26 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | The Bacillus anthracis arylamine N-acetyltransferase ((BACAN)NAT1) that inactivates sulfamethoxazole, reveals unusual structural features compared with the other NAT isoenzymes.
Febs Lett., 585, 2011
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8OG2
 | | Crystal structure of CREBBP histone acetyltransferase domain in complex with Coenzyme A | | 分子名称: | COENZYME A, SODIUM ION, SULFATE ION, ... | | 著者 | Mechaly, A.E, Zhang, W, Haouz, A, Green, M, Rodrigues-Lima, F. | | 登録日 | 2023-03-17 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.47 Å) | | 主引用文献 | Crystal structure of CREBBP histone acetyltransferase domain in complex with Coenzyme A
To Be Published
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4GUZ
 | | Structure of the arylamine N-acetyltransferase from Mycobacterium abscessus | | 分子名称: | Probable arylamine n-acetyl transferase | | 著者 | Kubiak, X, Li de la Sierra-Gallay, I, Haouz, A, Weber, P, Rodrigues-Lima, F. | | 登録日 | 2012-08-30 | | 公開日 | 2013-10-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural and functional characterization of an arylamine N-acetyltransferase from the pathogen Mycobacterium abscessus: differences from other mycobacterial isoforms and implications for selective inhibition.
Acta Crystallogr.,Sect.D, 70, 2014
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4NV8
 | | Crystal Structure of Mesorhizobium Loti Arylamine N-acetyltransferase F42W Mutant | | 分子名称: | Arylamine N-acetyltransferase | | 著者 | Xu, X.M, Haouz, A, Weber, P, Li de la sierra-gallay, I, Kubiak, X, Dupret, J.-M, Rodrigues-lima, F. | | 登録日 | 2013-12-05 | | 公開日 | 2015-01-21 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Insight into cofactor recognition in arylamine N-acetyltransferase enzymes: structure of Mesorhizobium loti arylamine N-acetyltransferase in complex with coenzyme A.
Acta Crystallogr.,Sect.D, 71, 2015
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4NV7
 | | Crystal Structure of Mesorhizobium Loti Arylamine N-acetyltransferase 1 In Complex With CoA | | 分子名称: | Arylamine N-acetyltransferase, COENZYME A | | 著者 | Xu, X.M, Haouz, A, Weber, P, Li de la sierra-gallay, I, Kubiak, X, Dupret, J.-M, Rodrigues-lima, F. | | 登録日 | 2013-12-05 | | 公開日 | 2015-01-21 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | | 主引用文献 | Insight into cofactor recognition in arylamine N-acetyltransferase enzymes: structure of Mesorhizobium loti arylamine N-acetyltransferase in complex with coenzyme A.
Acta Crystallogr.,Sect.D, 71, 2015
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4DMO
 | | Crystal structure of the (BACCR)NAT3 arylamine N-acetyltransferase from Bacillus cereus reveals a unique Cys-His-Glu catalytic triad | | 分子名称: | 3-(1-methylpiperidinium-1-yl)propane-1-sulfonate, N-hydroxyarylamine O-acetyltransferase | | 著者 | Kubiak, X, Li de la Sierra-Gallay, I, Haouz, A, Weber, P, Rodrigues-Lima, F. | | 登録日 | 2012-02-08 | | 公開日 | 2013-06-26 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Structural and Biochemical Characterization of an Active Arylamine N-Acetyltransferase Possessing a Non-canonical Cys-His-Glu Catalytic Triad.
J.Biol.Chem., 288, 2013
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5IKP
 | | Crystal structure of human brain glycogen phosphorylase bound to AMP | | 分子名称: | ADENOSINE MONOPHOSPHATE, Glycogen phosphorylase, brain form, ... | | 著者 | Mathieu, C, Li de la Sierra-Gallay, I, Xu, X, Haouz, A, Rodrigues-Lima, F. | | 登録日 | 2016-03-03 | | 公開日 | 2016-07-20 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Insights into Brain Glycogen Metabolism: THE STRUCTURE OF HUMAN BRAIN GLYCOGEN PHOSPHORYLASE.
J.Biol.Chem., 291, 2016
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5IKO
 | | Crystal structure of human brain glycogen phosphorylase | | 分子名称: | Glycogen phosphorylase, brain form, HEXAETHYLENE GLYCOL, ... | | 著者 | Mathieu, C, Li de la Sierra-Gallay, I, Xu, X, Haouz, A, Rodrigues-Lima, F. | | 登録日 | 2016-03-03 | | 公開日 | 2016-07-20 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Insights into Brain Glycogen Metabolism: THE STRUCTURE OF HUMAN BRAIN GLYCOGEN PHOSPHORYLASE.
J.Biol.Chem., 291, 2016
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1W4T
 | | X-ray crystallographic structure of Pseudomonas aeruginosa arylamine N-acetyltransferase | | 分子名称: | Arylamine N-acetyltransferase, SULFATE ION | | 著者 | Westwood, I.M, Holton, S.J, Rodrigues-Lima, F, Dupret, J.-M, Bhakta, S, Noble, M.E, Sim, E. | | 登録日 | 2004-07-29 | | 公開日 | 2005-08-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Expression, purification, characterization and structure of Pseudomonas aeruginosa arylamine N-acetyltransferase.
Biochem. J., 385, 2005
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8CN0
 | | Crystal structure of CREBBP-Y1482N histone acetyltransferase domain in complex with Coenzyme A | | 分子名称: | COENZYME A, ZINC ION, histone acetyltransferase | | 著者 | Mechaly, A.E, Zhang, W, Haouz, A, Green, M, Rodrigues-Lima, F. | | 登録日 | 2023-02-21 | | 公開日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | | 主引用文献 | Crystal structure of CREBBP-Y1482N histone acetyltransferase domain in complex with Coenzyme A
To Be Published
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8CNB
 | | Crystal structure of CREBBP-Y1503C histone acetyltransferase domain in complex with Coenzyme A | | 分子名称: | COENZYME A, ZINC ION, histone acetyltransferase | | 著者 | Mechaly, A.E, Zhang, W, Haouz, A, Green, M, Rodrigues-Lima, F. | | 登録日 | 2023-02-22 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.986 Å) | | 主引用文献 | Crystal structure of CREBBP-Y1503C histone acetyltransferase domain in complex with Coenzyme A
To Be Published
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8CNA
 | | Crystal structure of CREBBP-R1446C histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA | | 分子名称: | ZINC ION, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R,20R)-20-carbamoyl-3-hydroxy-2,2-dimethyl-4,8,14,22-tetraoxo-12-thia-5,9,15,21-tetraazatricos-1-yl dihydrogen diphosphate, histone acetyltransferase | | 著者 | Mechaly, A.E, Zhang, W, Haouz, A, Green, M, Rodrigues-Lima, F. | | 登録日 | 2023-02-22 | | 公開日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.463 Å) | | 主引用文献 | Crystal structure of CREBBP-R1446C histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA
To Be Published
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8CND
 | | Crystal structure of CREBBP-Y1482N histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA | | 分子名称: | ZINC ION, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R,20R)-20-carbamoyl-3-hydroxy-2,2-dimethyl-4,8,14,22-tetraoxo-12-thia-5,9,15,21-tetraazatricos-1-yl dihydrogen diphosphate, histone acetyltransferase | | 著者 | Mechaly, A.E, Zhang, W, Haouz, A, Green, M, Rodrigues-Lima, F. | | 登録日 | 2023-02-22 | | 公開日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.972 Å) | | 主引用文献 | Crystal structure of CREBBP-Y1482N histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA
To Be Published
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8CMZ
 | | Crystal structure of CREBBP-R1446C histone acetyltransferase domain in complex with Coenzyme A | | 分子名称: | COENZYME A, ZINC ION, histone acetyltransferase | | 著者 | Mechaly, A.E, Zhang, W, Haouz, A, Green, M, Rodrigues-Lima, F. | | 登録日 | 2023-02-21 | | 公開日 | 2024-03-06 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.252 Å) | | 主引用文献 | Crystal structure of CREBBP-R1446C histone acetyltransferase domain in complex with Coenzyme A
To Be Published
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2BYE
 | | NMR solution structure of phospholipase c epsilon RA 1 domain | | 分子名称: | PHOSPHOLIPASE C, EPSILON 1 | | 著者 | Bunney, T.D, Harris, R, Gandarillas, N.L, Josephs, M.B, Roe, S.M, Paterson, H.F, Rodrigues-Lima, F, Esposito, D, Gieschik, P, Pearl, L.H, Driscoll, P.C, Katan, M. | | 登録日 | 2005-08-01 | | 公開日 | 2006-02-22 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural and Mechanistic Insights Into Ras Association Domains of Phospholipase C Epsilon.
Mol.Cell, 21, 2006
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2BYF
 | | NMR solution structure of phospholipase c epsilon RA 2 domain | | 分子名称: | PHOSPHOLIPASE C, EPSILON 1 | | 著者 | Bunney, T.D, Harris, R, Gandarillas, N.L, Josephs, M.B, Roe, S.M, Paterson, H.F, Rodrigues-Lima, F, Esposito, D, Gieschik, P, Pearl, L.H, Driscoll, P.C, Katan, M. | | 登録日 | 2005-08-01 | | 公開日 | 2006-02-22 | | 最終更新日 | 2024-06-19 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural and Mechanistic Insights Into Ras Association Domains of Phospholipase C Epsilon.
Mol.Cell, 21, 2006
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2BSZ
 | | Structure of Mesorhizobium loti arylamine N-acetyltransferase 1 | | 分子名称: | ARYLAMINE N-ACETYLTRANSFERASE 1 | | 著者 | Holton, S.J, Dairou, J, Sandy, J, Rodrigues-Lima, F, Dupret, J.-M, Noble, M.E.M, Sim, E. | | 登録日 | 2005-05-24 | | 公開日 | 2005-05-25 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of Mesorhizobium Loti Arylamine N-Acetyltransferase 1.
Acta Crystallogr.,Sect.F, 61, 2005
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6ZZ4
 | | Crystal structure of the PTPN2 C216G mutant | | 分子名称: | PHOSPHATE ION, Tyrosine-protein phosphatase non-receptor type 2 | | 著者 | Mechaly, A.E, Berthelet, J, Nian, Q, Parlato, M, Cerf-Bensussan, N, Haouz, A, Rodrigues-Lima, F. | | 登録日 | 2020-08-03 | | 公開日 | 2021-08-18 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | | 主引用文献 | Structural characterization of a pathogenic mutant of human protein tyrosine phosphatase PTPN2 (Cys216Gly) that causes very early onset autoimmune enteropathy.
Protein Sci., 31, 2022
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2W2T
 | | Rac2 (G12V) in complex with GDP | | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2 | | 著者 | Opaleye, O, Bunney, T.D, Roe, S.M, Pearl, L.H. | | 登録日 | 2008-11-04 | | 公開日 | 2009-05-05 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Structural Insights Into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2.
Mol.Cell, 34, 2009
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2W2V
 | | Rac2 (G12V) in complex with GTPgS | | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, RAS-RELATED C3 BOTULINUM TOXIN SUBSTRATE 2 | | 著者 | Opaleye, O, Bunney, T.D, Roe, S.M, Pearl, L.H. | | 登録日 | 2008-11-04 | | 公開日 | 2009-05-05 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural Insights Into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2.
Mol.Cell, 34, 2009
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2W2W
 | | PLCg2 Split Pleckstrin Homology (PH) Domain | | 分子名称: | 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-2 | | 著者 | Opaleye, O, Bunney, T.D, Roe, S.M, Pearl, L.H. | | 登録日 | 2008-11-04 | | 公開日 | 2009-05-05 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural Insights Into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2.
Mol.Cell, 34, 2009
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2W2X
 | | Complex of Rac2 and PLCg2 spPH Domain | | 分子名称: | 1-PHOSPHATIDYLINOSITOL-4,5-BISPHOSPHATE PHOSPHODIESTERASE GAMMA-2, 5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Opaleye, O, Bunney, T.D, Roe, S.M, Pearl, L.H. | | 登録日 | 2008-11-04 | | 公開日 | 2009-05-05 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural Insights Into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2.
Mol.Cell, 34, 2009
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2C5L
 | | Structure of PLC epsilon Ras association domain with hRas | | 分子名称: | GLYCEROL, GTPASE HRAS, GUANOSINE-5'-TRIPHOSPHATE, ... | | 著者 | Roe, S.M, Bunney, T.D, Katan, M, Pearl, L.H. | | 登録日 | 2005-10-27 | | 公開日 | 2006-02-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and Mechanistic Insights Into Ras Association Domains of Phospholipase C Epsilon
Mol.Cell, 21, 2006
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1W5R
 | | X-ray crystallographic structure of a C70Q Mycobacterium smegmatis N- arylamine Acetyltransferase | | 分子名称: | ARYLAMINE N-ACETYLTRANSFERASE | | 著者 | Holton, S.J, Sandy, J, Rodrigues-Lima, F, Dupret, J.-M, Bhakta, S, Noble, M.E.M, Sim, E. | | 登録日 | 2004-08-09 | | 公開日 | 2005-05-11 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | Investigation of the Catalytic Triad of Arylamine N-Acetyltransferases: Essential Residues Required for Acetyl Transfer to Arylamines.
Biochem.J., 390, 2005
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