6R63
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![BU of 6r63 by Molmil](/molmil-images/mine/6r63) | Crystal structure of indoleamine 2,3-dioxygenase 1 (IDO1) in complex with ferric heme and MMG-0358 | 分子名称: | 4-chloranyl-2-(2~{H}-1,2,3-triazol-4-yl)phenol, Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Roehrig, U.F, Reynaud, A, Pojer, F, Michielin, O, Zoete, V. | 登録日 | 2019-03-26 | 公開日 | 2019-10-02 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.894 Å) | 主引用文献 | Inhibition Mechanisms of Indoleamine 2,3-Dioxygenase 1 (IDO1). J.Med.Chem., 62, 2019
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2XBZ
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![BU of 2xbz by Molmil](/molmil-images/mine/2xbz) | Multiple oligomeric forms of the Pseudomonas aeruginosa RetS sensor domain modulate accessibility to the ligand-binding site | 分子名称: | RETS-HYBRID SENSOR KINASE | 著者 | Vincent, F, Round, A, Reynaud, A, Bordi, C, Filloux, A, Bourne, Y. | 登録日 | 2010-04-15 | 公開日 | 2010-06-30 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Distinct Oligomeric Forms of the Pseudomonas Aeruginosa Rets Sensor Domain Modulate Accessibility to the Ligand Binding Site. Environ.Microbiol., 12, 2010
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5OC7
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![BU of 5oc7 by Molmil](/molmil-images/mine/5oc7) | Crystal structure of the pleckstrin-homology domain of Bcr-Abl in complex with monobody Mb(Bcr-PH_4). | 分子名称: | Breakpoint cluster region protein,pleckstrin-homology domain of Bcr-Abl, D-MYO-INOSITOL-4,5-BISPHOSPHATE, GLYCEROL, ... | 著者 | Reckel, S, Reynaud, A, Pojer, F, Hantschel, O. | 登録日 | 2017-06-29 | 公開日 | 2017-12-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.652 Å) | 主引用文献 | Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase. Nat Commun, 8, 2017
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5N7E
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![BU of 5n7e by Molmil](/molmil-images/mine/5n7e) | Crystal structure of the Dbl-homology domain of Bcr-Abl in complex with monobody Mb(Bcr-DH_4). | 分子名称: | Breakpoint cluster region protein, Mb(Bcr-DH_4) | 著者 | Reckel, S, Reynaud, A, Pojer, F, Hantschel, O. | 登録日 | 2017-02-20 | 公開日 | 2017-12-27 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.647 Å) | 主引用文献 | Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase. Nat Commun, 8, 2017
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4EGW
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![BU of 4egw by Molmil](/molmil-images/mine/4egw) | The structure of the soluble domain of CorA from Methanocaldococcus jannaschii | 分子名称: | 1,4-BUTANEDIOL, HEXANE-1,6-DIOL, MAGNESIUM ION, ... | 著者 | Guskov, A, Nordin, N, Reynaud, A, Engman, H, Lundback, A.-K, Jong, A.J.O, Cornvik, T, Phua, T, Eshaghi, S. | 登録日 | 2012-04-02 | 公開日 | 2012-10-31 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural insights into the mechanisms of Mg2+ uptake, transport, and gating by CorA Proc.Natl.Acad.Sci.USA, 109, 2012
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4EV6
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![BU of 4ev6 by Molmil](/molmil-images/mine/4ev6) | The complete structure of CorA magnesium transporter from Methanocaldococcus jannaschii | 分子名称: | MAGNESIUM ION, Magnesium transport protein CorA, UNDECYL-MALTOSIDE | 著者 | Guskov, A, Nordin, N, Reynaud, A, Engman, H, Lundback, A.-K, Jong, A.J.O, Cornvik, T, Phua, T, Eshaghi, S. | 登録日 | 2012-04-25 | 公開日 | 2012-10-31 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural insights into the mechanisms of Mg2+ uptake, transport, and gating by CorA Proc.Natl.Acad.Sci.USA, 109, 2012
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7AH4
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![BU of 7ah4 by Molmil](/molmil-images/mine/7ah4) | Crystal structure of indoleamine 2,3-dioxygenase 1 (IDO1) in complex with ferric heme and MMG-0363 | 分子名称: | 4-chloranyl-2-(2~{H}-1,2,3-triazol-4-yl)aniline, Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Roehrig, U.F, Reynaud, A, Pojer, F, Michielin, O, Zoete, V. | 登録日 | 2020-09-24 | 公開日 | 2021-02-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.401 Å) | 主引用文献 | Azole-Based Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors. J.Med.Chem., 64, 2021
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7AH6
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![BU of 7ah6 by Molmil](/molmil-images/mine/7ah6) | Crystal structure of indoleamine 2,3-dioxygenase 1 (IDO1) in complex with ferric heme and MMG-0752 | 分子名称: | 4-bromanyl-2-(4~{H}-1,2,4-triazol-3-yl)aniline, GLYCEROL, Indoleamine 2,3-dioxygenase 1, ... | 著者 | Roehrig, U.F, Reynaud, A, Pojer, F, Michielin, O, Zoete, V. | 登録日 | 2020-09-24 | 公開日 | 2021-02-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.998 Å) | 主引用文献 | Azole-Based Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors. J.Med.Chem., 64, 2021
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7AH5
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![BU of 7ah5 by Molmil](/molmil-images/mine/7ah5) | Crystal structure of indoleamine 2,3-dioxygenase 1 (IDO1) in complex with ferric heme and MMG-0706 | 分子名称: | 4-chloranyl-2-(1~{H}-1,2,4-triazol-5-yl)aniline, Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Roehrig, U.F, Reynaud, A, Pojer, F, Michielin, O, Zoete, V. | 登録日 | 2020-09-24 | 公開日 | 2021-02-17 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Azole-Based Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors. J.Med.Chem., 64, 2021
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7ZV3
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![BU of 7zv3 by Molmil](/molmil-images/mine/7zv3) | Crystal structure of indoleamine 2,3-dioxygenase 1 (IDO1) in complex with ferric heme and MMG-0472 | 分子名称: | 4-(3-chloro-2-phenethylphenyl)-1H-1,2,3-triazole, GLYCEROL, Indoleamine 2,3-dioxygenase 1, ... | 著者 | Roehrig, U.F, Reynaud, A, Pojer, F, Michielin, O, Zoete, V. | 登録日 | 2022-05-13 | 公開日 | 2022-07-06 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.551 Å) | 主引用文献 | Structure-based optimization of type III indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors. J Enzyme Inhib Med Chem, 37, 2022
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5N6R
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![BU of 5n6r by Molmil](/molmil-images/mine/5n6r) | Solution structure of the Dbl-homology domain of Bcr-Abl | 分子名称: | Breakpoint cluster region protein | 著者 | Reckel, S, Lohr, F, Buchner, L, Guntert, P, Dotsch, V, Hantschel, O. | 登録日 | 2017-02-16 | 公開日 | 2017-12-27 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural and functional dissection of the DH and PH domains of oncogenic Bcr-Abl tyrosine kinase. Nat Commun, 8, 2017
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6TLC
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![BU of 6tlc by Molmil](/molmil-images/mine/6tlc) | Unphosphorylated human STAT3 in complex with MS3-6 monobody | 分子名称: | Monobody, Signal transducer and activator of transcription 3 | 著者 | La Sala, G, Lau, K, Reynaud, A, Pojer, F, Hantschel, O. | 登録日 | 2019-12-02 | 公開日 | 2020-07-22 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Selective inhibition of STAT3 signaling using monobodies targeting the coiled-coil and N-terminal domains. Nat Commun, 11, 2020
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