2WVP
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![BU of 2wvp by Molmil](/molmil-images/mine/2wvp) | Synthetically modified OmpG | 分子名称: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, 1,2-ETHANEDIOL, N-[2-({[5-(DIMETHYLAMINO)NAPHTHALEN-1-YL]SULFONYL}AMINO)ETHYL]-2-IODOACETAMIDE, ... | 著者 | Grosse, W, Reiss, P, Reitz, S, Cebi, M, Luebben, W, Koert, U, Essen, L.-O. | 登録日 | 2009-10-19 | 公開日 | 2010-07-14 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural and Functional Characterization of a Synthetically Modified Ompg. Bioorg.Med.Chem., 18, 2010
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1TKQ
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![BU of 1tkq by Molmil](/molmil-images/mine/1tkq) | SOLUTION STRUCTURE OF A LINKED UNSYMMETRIC GRAMICIDIN IN A MEMBRANE-ISOELECTRICAL SOLVENTS MIXTURE IN THE PRESENCE OF CsCl | 分子名称: | GRAMICIDIN A, MINI-GRAMICIDIN A, SUCCINIC ACID | 著者 | Xie, X, Al-Momani, L, Bockelmann, D, Griesinger, C, Koert, U. | 登録日 | 2004-06-09 | 公開日 | 2004-07-13 | 最終更新日 | 2019-09-25 | 実験手法 | SOLUTION NMR | 主引用文献 | An Asymmetric Ion Channel Derived from Gramicidin A. Synthesis, Function and NMR Structure. FEBS J., 272, 2005
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3FYX
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![BU of 3fyx by Molmil](/molmil-images/mine/3fyx) | The Structure of OmpF porin with a synthetic dibenzo-18-crown-6 as modulator | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, N-(6,7,9,10,17,18,20,21-octahydrodibenzo[b,k][1,4,7,10,13,16]hexaoxacyclooctadecin-2-yl)acetamide, Outer membrane protein F | 著者 | Reitz, S, Cebi, M, Koert, U, Essen, L.O. | 登録日 | 2009-01-23 | 公開日 | 2009-06-30 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | On the function and structure of synthetically modified porins. Angew.Chem.Int.Ed.Engl., 48, 2009
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4CTD
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![BU of 4ctd by Molmil](/molmil-images/mine/4ctd) | |
8SGE
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![BU of 8sge by Molmil](/molmil-images/mine/8sge) | KLHDC2 Kelch Domain with ligand KDRLKZ-1 | 分子名称: | GLYCEROL, Kelch domain-containing protein 2, [(5P)-5-{3-[(2R)-butan-2-yl]-7-[(2-methoxyethoxy)carbonyl]-2-oxo-5,6,7,8-tetrahydro-1,7-naphthyridin-1(2H)-yl}-2-oxopyridin-1(2H)-yl]acetic acid | 著者 | Digianantonio, K.M, Bekes, M, Langley, D.R, Zimmerman, K. | 登録日 | 2023-04-12 | 公開日 | 2024-01-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.509 Å) | 主引用文献 | Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules. Nat.Struct.Mol.Biol., 31, 2024
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8SGF
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![BU of 8sgf by Molmil](/molmil-images/mine/8sgf) | KLHDC2 Kelch Domain with KLHDC2 c-terminal peptide bound | 分子名称: | GLYCEROL, HIS-SER-VAL-ASN-GLN-ARG-PHE-GLY-SER-ASN-ASN-THR-SER-GLY-SER, Kelch domain-containing protein 2 | 著者 | Digianantonio, K.M, Bekes, M, Langley, D.R, Zimmerman, K. | 登録日 | 2023-04-12 | 公開日 | 2024-01-03 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.418 Å) | 主引用文献 | Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules. Nat.Struct.Mol.Biol., 31, 2024
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8SH2
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![BU of 8sh2 by Molmil](/molmil-images/mine/8sh2) | KLHDC2 in complex with EloB and EloC | 分子名称: | Elongin-B, Elongin-C, Kelch domain-containing protein 2 | 著者 | Digianantonio, K.M, Bekes, M. | 登録日 | 2023-04-13 | 公開日 | 2024-01-03 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (3.74 Å) | 主引用文献 | Co-opting the E3 ligase KLHDC2 for targeted protein degradation by small molecules. Nat.Struct.Mol.Biol., 31, 2024
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7T1G
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![BU of 7t1g by Molmil](/molmil-images/mine/7t1g) | Crystal structure of CAB1 Pantothenate Kinase from Saccharomyces cerevisiae in complex with compound YU385595 | 分子名称: | (8S)-N~2~-[(4-tert-butylphenyl)methyl]-N~7~,N~7~-dimethyl-5-[(morpholin-4-yl)methyl][1,2,4]triazolo[1,5-a]pyrimidine-2,7-diamine, Pantothenate kinase CAB1 | 著者 | Gihaz, S, Ben Mamoun, C. | 登録日 | 2021-12-01 | 公開日 | 2022-10-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | High-resolution crystal structure and chemical screening reveal pantothenate kinase as a new target for antifungal development. Structure, 30, 2022
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7T1H
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![BU of 7t1h by Molmil](/molmil-images/mine/7t1h) | Crystal structure of CAB1 Pantothenate Kinase from Saccharomyces cerevisiae in complex with compound YU281445 | 分子名称: | (8R)-2-{[(4-tert-butylphenyl)methyl]amino}-5-[(morpholin-4-yl)methyl][1,2,4]triazolo[1,5-a]pyrimidin-7(4H)-one, GLYCEROL, Pantothenate kinase CAB1 | 著者 | Gihaz, S, Ben Mamoun, C. | 登録日 | 2021-12-01 | 公開日 | 2022-10-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | High-resolution crystal structure and chemical screening reveal pantothenate kinase as a new target for antifungal development. Structure, 30, 2022
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7T1I
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![BU of 7t1i by Molmil](/molmil-images/mine/7t1i) | Crystal structure of CAB1 Pantothenate Kinase from Saccharomyces cerevisiae in complex with compound YU385597 | 分子名称: | (8S)-2-{[(4-tert-butylphenyl)methyl]amino}-5-[(piperidin-1-yl)methyl][1,2,4]triazolo[1,5-a]pyrimidin-7(6H)-one, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... | 著者 | Gihaz, S, Ben Mamoun, C. | 登録日 | 2021-12-02 | 公開日 | 2022-10-05 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | High-resolution crystal structure and chemical screening reveal pantothenate kinase as a new target for antifungal development. Structure, 30, 2022
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