4IEC
 
 | | Cys105 covalent modification by 2-hydroxyethyl disulfide in Mycobacterium tuberculosis methionine aminopeptidase Type 1c | | 分子名称: | COBALT (II) ION, Methionine aminopeptidase 2, POTASSIUM ION | | 著者 | Reddi, R, Gumpena, R, Kishor, C, Addlagatta, A. | | 登録日 | 2012-12-13 | | 公開日 | 2013-12-18 | | 最終更新日 | 2019-11-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents
Febs J., 281, 2014
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4IDY
 | | Mycobacterium Tuberculosis Methionine aminopeptidase Type 1c in complex with 2-hydroxyethyl disulfide | | 分子名称: | 2-HYDROXYETHYL DISULFIDE, Methionine aminopeptidase 2, POTASSIUM ION | | 著者 | Reddi, R, Gumpena, R, Kishor, C, Addlagatta, A. | | 登録日 | 2012-12-13 | | 公開日 | 2013-12-18 | | 最終更新日 | 2015-02-04 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents
Febs J., 281, 2014
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4IF7
 | | Mycobacterium Tuberculosis Methionine aminopeptidase Type 1c in complex with homocysteine-methyl disulfide | | 分子名称: | (2S)-2-amino-4-(methyldisulfanyl)butanoic acid, COBALT (II) ION, Methionine aminopeptidase 2 | | 著者 | Reddi, R, Gumpena, R, Kishor, C, Addlagatta, A. | | 登録日 | 2012-12-14 | | 公開日 | 2013-12-18 | | 最終更新日 | 2019-11-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents
Febs J., 281, 2014
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4X5K
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8THN
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8DHR
 | | An ester mutant of SfGFP | | 分子名称: | Green fluorescent protein | | 著者 | Reddi, R, Valiyaveetil, F.I. | | 登録日 | 2022-06-28 | | 公開日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | A facile approach for incorporating tyrosine esters to probe ion-binding sites and backbone hydrogen bonds.
J.Biol.Chem., 300, 2023
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7M2J
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7M2H
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7M2I
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4OOK
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7RP0
 | | Structural Snapshots of Intermediates in the Gating of a K+ Channel | | 分子名称: | DIACYL GLYCEROL, KcsA Fab chain A, KcsA Fab chain B, ... | | 著者 | Reddi, R, Matulef, K, Riederer, E.A, Valiyaveetil, F.I. | | 登録日 | 2021-08-02 | | 公開日 | 2021-10-27 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | | 主引用文献 | Structures of Gating Intermediates in a K + channell.
J.Mol.Biol., 433, 2021
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7SIZ
 | | C-type inactivation in a voltage gated K+ channel | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION, Voltage gated potassium channel Kv1.2-Kv2.1, ... | | 著者 | Reddi, R, Riederer, E.A, Matulef, K, Whorton, M.R, Valiyaveetil, F.I. | | 登録日 | 2021-10-15 | | 公開日 | 2022-05-04 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural basis for C-type inactivation in a Shaker family voltage-gated K + channel.
Sci Adv, 8, 2022
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7SIT
 | | Crystal structure of Voltage gated potassium ion channel, Kv 1.2 chimera-3m | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, OXYGEN ATOM, POTASSIUM ION, ... | | 著者 | Reddi, R, Matulef, K, Riederer, E.A, Whorton, M.R, Valiyaveetil, F.I. | | 登録日 | 2021-10-14 | | 公開日 | 2022-05-04 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.32 Å) | | 主引用文献 | Structural basis for C-type inactivation in a Shaker family voltage-gated K + channel.
Sci Adv, 8, 2022
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3ROR
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4Q4I
 | | Crystal structure of E.coli aminopeptidase N in complex with amastatin | | 分子名称: | Amastatin, Aminopeptidase N, GLYCEROL, ... | | 著者 | Reddi, R, Ganji, R.J, Addlagatta, A. | | 登録日 | 2014-04-14 | | 公開日 | 2015-04-15 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Structural basis for the inhibition of M1 family aminopeptidases by the natural product actinonin: Crystal structure in complex with E. coli aminopeptidase N.
Protein Sci., 24, 2015
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5YQB
 | | Crystal structure of E.coli aminopeptidase N in complex with Puromycin | | 分子名称: | (2R,3R,4S,5S)-4-AMINO-2-[6-(DIMETHYLAMINO)-9H-PURIN-9-YL]-5-(HYDROXYMETHYL)TETRAHYDRO-3-FURANOL, Aminopeptidase N, GLYCEROL, ... | | 著者 | Marapaka, A.K, Ganji, R.J, Reddi, R, Addlagatta, A. | | 登録日 | 2017-11-06 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Puromycin, a selective inhibitor of PSA acts as a substrate for other M1 family aminopeptidases: Biochemical and structural basis
Int.J.Biol.Macromol., 165, 2020
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5YO1
 | | Structure of ePepN E298A mutant in complex with Puromycin | | 分子名称: | Aminopeptidase N, GLYCEROL, PUROMYCIN, ... | | 著者 | Ganji, R.J, Reddi, R, Marapaka, A.K, Addlagatta, A. | | 登録日 | 2017-10-26 | | 公開日 | 2018-11-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Puromycin, a selective inhibitor of PSA acts as a substrate for other M1 family aminopeptidases: Biochemical and structural basis
Int.J.Biol.Macromol., 165, 2020
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4Q4E
 | | Crystal structure of E.coli aminopeptidase N in complex with actinonin | | 分子名称: | ACTINONIN, Aminopeptidase N, GLYCEROL, ... | | 著者 | Reddi, R, Ganji, R.J, Addlagatta, A. | | 登録日 | 2014-04-14 | | 公開日 | 2015-04-15 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis for the inhibition of M1 family aminopeptidases by the natural product actinonin: Crystal structure in complex with E. coli aminopeptidase N.
Protein Sci., 24, 2015
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3TB5
 | | Crystal Structure of the Enterococcus faecalis Methionine aminopeptidase apo form | | 分子名称: | CITRIC ACID, Methionine aminopeptidase | | 著者 | Kishor, C, Gumpena, R, Reddi, R, Addlagatta, A. | | 登録日 | 2011-08-05 | | 公開日 | 2012-08-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural studies of Enterococcus faecalis methionine aminopeptidase and design of microbe specific 2,2'-bipyridine based inhibitors
MEDCHEMCOMM, 3, 2012
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5YQ1
 | | Crystal structure of E.coli aminopeptidase N in complex with O-Methyl-L-tyrosine | | 分子名称: | Aminopeptidase N, GLYCEROL, MALONATE ION, ... | | 著者 | Marapaka, A.K, Ganji, R.J, Reddi, R, Addlagatta, A. | | 登録日 | 2017-11-04 | | 公開日 | 2018-11-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.58 Å) | | 主引用文献 | Crystal structure of E.coli aminopeptidase N in complex with O-Methyl-L-tyrosine
To Be Published
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5YQ2
 | | Crystal structure of E.coli aminopeptidase N in complex with Puromycin aminonucleoside | | 分子名称: | (2R,3R,4S,5S)-4-AMINO-2-[6-(DIMETHYLAMINO)-9H-PURIN-9-YL]-5-(HYDROXYMETHYL)TETRAHYDRO-3-FURANOL, Aminopeptidase N, GLYCEROL, ... | | 著者 | Marapaka, A.K, Ganji, R.J, Reddi, R, Addlagatta, A. | | 登録日 | 2017-11-04 | | 公開日 | 2018-11-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Crystal structure of E.coli aminopeptidase N in complex with Puromycin aminonucleoside
To Be Published
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7O2O
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4IKT
 | | Crystal structure of truncated (delta 1-89) human methionine aminopeptidase Type 1 in complex with N1-(5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl)-N2-(5-(trifluoromethyl)pyridin-2-yl)ethane-1,2-diamine | | 分子名称: | COBALT (II) ION, GLYCEROL, Methionine aminopeptidase 1, ... | | 著者 | Addlagatta, A, Kishor, C, Arya, T. | | 登録日 | 2012-12-28 | | 公開日 | 2013-12-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Identification, Biochemical and Structural Evaluation of Species-Specific Inhibitors against Type I Methionine Aminopeptidases
J.Med.Chem., 56, 2013
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4IKS
 | | Crystal structure of truncated (delta 1-89) human methionine aminopeptidase Type 1 in complex with N1-(5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl)-N2-(6-(trifluoromethyl)pyridin-2-yl)ethane-1,2-diamine | | 分子名称: | COBALT (II) ION, GLYCEROL, Methionine aminopeptidase 1, ... | | 著者 | Addlagatta, A, Kishor, C, Arya, T. | | 登録日 | 2012-12-28 | | 公開日 | 2013-12-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Identification, Biochemical and Structural Evaluation of Species-Specific Inhibitors against Type I Methionine Aminopeptidases
J.Med.Chem., 56, 2013
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4IKR
 | | Crystal structure of Type 1 human methionine aminopeptidase in complex with 2-(4-(5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl)piperazin-1-yl)ethanol | | 分子名称: | 2-{4-[5-chloro-6-methyl-2-(pyridin-2-yl)pyrimidin-4-yl]piperazin-1-yl}ethanol, COBALT (II) ION, GLYCEROL, ... | | 著者 | Addlagatta, A, Kishor, C, Arya, T. | | 登録日 | 2012-12-28 | | 公開日 | 2013-12-11 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Identification, Biochemical and Structural Evaluation of Species-Specific Inhibitors against Type I Methionine Aminopeptidases
J.Med.Chem., 56, 2013
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