2M7G
 
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2LP7
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2EXL
 | | GRP94 N-terminal Domain bound to geldanamycin | | 分子名称: | Endoplasmin, GELDANAMYCIN, PENTAETHYLENE GLYCOL, ... | | 著者 | Reardon, P.N, Immormino, R.M, Gewirth, D.T. | | 登録日 | 2005-11-08 | | 公開日 | 2006-10-24 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Different poses for ligand and chaperone in inhibitor-bound Hsp90 and GRP94: implications for paralog-specific drug design.
J.Mol.Biol., 388, 2009
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7UI5
 | | Evolution avoids a pathological stabilizing interaction in the immune protein S100A9 | | 分子名称: | CALCIUM ION, Protein S100-A9 | | 著者 | Reardon, P.N, Harman, J.L, Costello, S.M, Warren, G.D, Phillips, S.R, Connor, P.J, Marqusee, S, Harms, M.J. | | 登録日 | 2022-03-28 | | 公開日 | 2022-10-26 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Evolution avoids a pathological stabilizing interaction in the immune protein S100A9.
Proc.Natl.Acad.Sci.USA, 119, 2022
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2M7W
 | | Independently verified structure of gp41-M-MAT, a membrane associated MPER trimer from HIV-1 gp41 | | 分子名称: | Envelope glycoprotein | | 著者 | Martin, J.W, Reardon, P.N, Sage, H.S, Moses, D.S, Munir, A.S, Haynes, B.F, Spicer, L.D, Donald, B.R. | | 登録日 | 2013-05-01 | | 公開日 | 2013-05-15 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of an HIV-1-neutralizing antibody target, the lipid-bound gp41 envelope membrane proximal region trimer.
Proc.Natl.Acad.Sci.USA, 111, 2014
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2GFD
 | | GRP94 in complex with the novel HSP90 Inhibitor Radamide | | 分子名称: | Endoplasmin, METHYL 3-CHLORO-2-{3-[(2,5-DIHYDROXY-4-METHOXYPHENYL)AMINO]-3-OXOPROPYL}-4,6-DIHYDROXYBENZOATE, PENTAETHYLENE GLYCOL, ... | | 著者 | Immormino, R.M, Gewirth, D.T. | | 登録日 | 2006-03-21 | | 公開日 | 2007-04-03 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Different poses for ligand and chaperone in inhibitor-bound Hsp90 and GRP94: implications for paralog-specific drug design.
J.Mol.Biol., 388, 2009
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2ESA
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2FXS
 | | Yeast HSP82 in complex with the novel HSP90 Inhibitor Radamide | | 分子名称: | ATP-dependent molecular chaperone HSP82, GLYCEROL, METHYL 3-CHLORO-2-{3-[(2,5-DIHYDROXY-4-METHOXYPHENYL)AMINO]-3-OXOPROPYL}-4,6-DIHYDROXYBENZOATE | | 著者 | Immormino, R.M, Gewirth, D.T. | | 登録日 | 2006-02-06 | | 公開日 | 2007-02-06 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Different poses for ligand and chaperone in inhibitor-bound Hsp90 and GRP94: implications for paralog-specific drug design.
J.Mol.Biol., 388, 2009
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3C0E
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3C11
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