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The Complex of wild-type B-RAF with Pyrazolo pyrimidine inhibitor
分子名称:	B-Raf proto-oncogene serine/threonine-protein kinase, N-[3-(3-{4-[(dimethylamino)methyl]phenyl}pyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide, PHOSPHATE ION
著者	Xu, W, Breger, D, Torres, N, Dutia, M, Powell, D, Ciszewski, G.
登録日	2009-07-31
公開日	2009-11-10
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.79 Å)
主引用文献	Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors. Bioorg.Med.Chem.Lett., 19, 2009

Inhibition of S-adenosylhomocysteine Hydrolase by "acyclic sugar" Adenosine Analogue D-eritadenine
分子名称:	D-ERITADENINE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, S-ADENOSYL-L-HOMOCYSTEINE HYDROLASE
著者	Takusagawa, F, Huang, Y, Komoto, J, Takata, Y, Gomi, T, Ogawa, H, Fujioka, M, Powell, D.
登録日	2001-09-20
公開日	2001-10-17
最終更新日	2023-08-16
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	Inhibition of S-adenosylhomocysteine hydrolase by acyclic sugar adenosine analogue D-eritadenine. Crystal structure of S-adenosylhomocysteine hydrolase complexed with D-eritadenine. J.Biol.Chem., 277, 2002

Crystal Structure Of The Androgen Receptor Ligand Binding Domain In Complex With 5-(2-fluoro-4-hydroxyphenyl)-1-methyl-1H-pyrrole-2-carbonitrile
分子名称:	5-(2-fluoro-4-hydroxyphenyl)-1-methyl-1H-pyrrole-2-carbonitrile, Androgen receptor
著者	Parris, K, Unwalla, R.
登録日	2017-05-02
公開日	2018-03-14
最終更新日	2024-03-13
実験手法	X-RAY DIFFRACTION (2.35 Å)
主引用文献	Structure-Based Approach To Identify 5-[4-Hydroxyphenyl]pyrrole-2-carbonitrile Derivatives as Potent and Tissue Selective Androgen Receptor Modulators. J. Med. Chem., 60, 2017