1D7Q
| HUMAN TRANSLATION INITIATION FACTOR EIF1A | 分子名称: | PROTEIN (N-TERMINAL HISTIDINE TAG), TRANSLATION INITIATION FACTOR 1A | 著者 | Battiste, J.L, Pestova, T.V, Hellen, C.U.T, Wagner, G. | 登録日 | 1999-10-19 | 公開日 | 2000-03-17 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | The eIF1A solution structure reveals a large RNA-binding surface important for scanning function. Mol.Cell, 5, 2000
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7A01
| The Halastavi arva virus intergenic region IRES promotes translation by the simplest possible initiation mechanism | 分子名称: | 18S RIBOSOMAL RNA, 28S RIBOSOMAL RNA, 40S RIBOSOMAL PROTEIN ES21, ... | 著者 | Abaeva, I, Vicens, Q, Bochler, A, Soufari, H, Simonetti, A, Pestova, T.V, Hashem, Y, Hellen, C.U.T. | 登録日 | 2020-08-05 | 公開日 | 2020-12-30 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | The Halastavi arva Virus Intergenic Region IRES Promotes Translation by the Simplest Possible Initiation Mechanism. Cell Rep, 33, 2020
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5A5T
| Structure of mammalian eIF3 in the context of the 43S preinitiation complex | 分子名称: | EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT A, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT C, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT E, ... | 著者 | des-Georges, A, Dhote, V, Kuhn, L, Hellen, C.U.T, Pestova, T.V, Frank, J, Hashem, Y. | 登録日 | 2015-06-21 | 公開日 | 2015-09-09 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (6 Å) | 主引用文献 | Structure of Mammalian Eif3 in the Context of the 43S Preinitiation Complex. Nature, 525, 2015
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5A5U
| Structure of mammalian eIF3 in the context of the 43S preinitiation complex | 分子名称: | EUKARYOTIC INITIATION FACTOR 3, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT B, EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT I | 著者 | des-Georges, A, Dhote, V, Kuhn, L, Hellen, C.U.T, Pestova, T.V, Frank, J, Hashem, Y. | 登録日 | 2015-06-21 | 公開日 | 2015-09-09 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (9 Å) | 主引用文献 | Structure of Mammalian Eif3 in the Context of the 43S Preinitiation Complex. Nature, 525, 2015
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1HU3
| MIDDLE DOMAIN OF HUMAN EIF4GII | 分子名称: | EIF4GII | 著者 | Marcotrigiano, J, Lomakin, I, Pestova, T.V, Hellen, C.U.T, Sonenberg, N, Burley, S.K. | 登録日 | 2001-01-03 | 公開日 | 2001-02-21 | 最終更新日 | 2021-02-03 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | A conserved HEAT domain within eIF4G directs assembly of the translation initiation machinery. Mol.Cell, 7, 2001
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2IF1
| HUMAN TRANSLATION INITIATION FACTOR EIF1, NMR, 29 STRUCTURES | 分子名称: | EIF1 | 著者 | Fletcher, C.M, Hellen, C.U.T, Pestova, T.V, Wagner, G. | 登録日 | 1998-08-04 | 公開日 | 1999-05-18 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and interactions of the translation initiation factor eIF1. EMBO J., 18, 1999
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3J5Y
| Structure of the mammalian ribosomal pre-termination complex associated with eRF1-eRF3-GDPNP | 分子名称: | 5'-R(*AP*UP*UP*GP*UP*AP*AP*AP*AP*A)-3', Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, Eukaryotic peptide chain release factor subunit 1, ... | 著者 | des Georges, A, Hashem, Y, Unbehaun, A, Grassucci, R.A, Taylor, D, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2013-11-21 | 公開日 | 2013-12-25 | 最終更新日 | 2018-07-18 | 実験手法 | ELECTRON MICROSCOPY (9.7 Å) | 主引用文献 | Structure of the mammalian ribosomal pre-termination complex associated with eRF1*eRF3*GDPNP. Nucleic Acids Res., 42, 2014
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4C4Q
| Cryo-EM map of the CSFV IRES in complex with the small ribosomal 40S subunit and DHX29 | 分子名称: | INTERNAL RIBOSOMAL ENTRY SITE | 著者 | Hashem, Y, desGeorges, A, Dhote, V, Langlois, R, Liao, H.Y, Grassucci, R.A, Pestova, T.V, Hellen, C.U.T, Frank, J. | 登録日 | 2013-09-07 | 公開日 | 2013-10-30 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (8.5 Å) | 主引用文献 | Hepatitis-C-Virus-Like Internal Ribosome Entry Sites Displace Eif3 to Gain Access to the 40S Subunit Nature, 503, 2013
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4D61
| Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state | 分子名称: | 18S RRNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ... | 著者 | Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T. | 登録日 | 2014-11-07 | 公開日 | 2015-03-04 | 最終更新日 | 2017-08-30 | 実験手法 | ELECTRON MICROSCOPY (9 Å) | 主引用文献 | Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires. Mol.Cell, 57, 2015
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4D67
| Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state | 分子名称: | 28S RRNA, 5.8S RRNA, 5S RRNA, ... | 著者 | Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T. | 登録日 | 2014-11-10 | 公開日 | 2015-03-04 | 最終更新日 | 2019-10-23 | 実験手法 | ELECTRON MICROSCOPY (9 Å) | 主引用文献 | Cryo-Em Structures of Ribosomal 80S Complexes with Termination Factors and Cricket Paralysis Virus Ires Reveal the Ires in the Translocated State Mol.Cell, 57, 2015
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4D5N
| Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state | 分子名称: | CRICKET PARALYSIS VIRUS IRES RNA, EUKARYOTIC PEPTIDE CHAIN RELEASE FACTOR SUBUNIT 1 | 著者 | Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T. | 登録日 | 2014-11-06 | 公開日 | 2015-02-04 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (9 Å) | 主引用文献 | Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires. Mol.Cell, 57, 2015
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4D5L
| Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state | 分子名称: | 18S RRNA 2, 40S RIBOSOMAL PROTEIN ES1, 40S RIBOSOMAL PROTEIN ES10, ... | 著者 | Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T. | 登録日 | 2014-11-05 | 公開日 | 2015-02-04 | 最終更新日 | 2017-08-23 | 実験手法 | ELECTRON MICROSCOPY (9 Å) | 主引用文献 | Cryo-Em of Ribosomal 80S Complexes with Termination Factors Reveals the Translocated Cricket Paralysis Virus Ires. Mol.Cell, 57, 2015
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4D5Y
| Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state | 分子名称: | 28S Ribosomal RNA, 5.8S Ribosomal RNA, 5S Ribosomal RNA, ... | 著者 | Muhs, M, Hilal, T, Mielke, T, Skabkin, M.A, Sanbonmatsu, K.Y, Pestova, T.V, Spahn, C.M.T. | 登録日 | 2014-11-07 | 公開日 | 2015-03-04 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (9 Å) | 主引用文献 | Cryo-Em Structures of Ribosomal 80S Complexes with Termination Factors and Cricket Paralysis Virus Ires Reveal the Ires in the Translocated State Mol.Cell, 57, 2015
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7SYJ
| Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 4(delta dII) | 分子名称: | 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2021-11-25 | 公開日 | 2022-07-13 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
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7SYX
| Structure of the delta dII IRES eIF5B-containing 48S initiation complex, closed conformation. Structure 15(delta dII) | 分子名称: | 18S rRNA, 40S ribosomal protein S24, 40S ribosomal protein S25, ... | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2021-11-25 | 公開日 | 2022-07-13 | 最終更新日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
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7SYN
| Structure of the HCV IRES bound to the 40S ribosomal subunit, head opening. Structure 8(delta dII) | 分子名称: | 18S rRNA, 40S ribosomal protein S2, HCV IRES, ... | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2021-11-25 | 公開日 | 2022-07-13 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA To Be Published
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7SYL
| Structure of the HCV IRES bound to the 40S ribosomal subunit, closed conformation. Structure 6(delta dII) | 分子名称: | 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2021-11-25 | 公開日 | 2022-07-13 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
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7SYG
| Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 1(delta dII) | 分子名称: | 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S24, ... | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2021-11-25 | 公開日 | 2022-07-13 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | 主引用文献 | Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA To Be Published
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7SYW
| Structure of the wt IRES eIF5B-containing 48S initiation complex, closed conformation. Structure 15(wt) | 分子名称: | 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S21, ... | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2021-11-25 | 公開日 | 2022-07-13 | 最終更新日 | 2023-02-01 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
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7SYM
| Structure of the HCV IRES bound to the 40S ribosomal subunit, head opening. Structure 7(delta dII) | 分子名称: | 18S rRNA, 40S ribosomal protein S2, 40S ribosomal protein S21, ... | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2021-11-25 | 公開日 | 2022-07-13 | 最終更新日 | 2024-02-28 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | Comprehensive structural overview of the HCV IRES-mediated translation initiation pathway To Be Published
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7SYI
| Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 3(delta dII) | 分子名称: | 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2021-11-25 | 公開日 | 2022-07-13 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | 主引用文献 | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
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7SYK
| Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 5(delta dII) | 分子名称: | 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2021-11-25 | 公開日 | 2022-07-13 | 最終更新日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
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7SYU
| Structure of the delta dII IRES w/o eIF2 48S initiation complex, closed conformation. Structure 13(delta dII) | 分子名称: | 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2021-11-25 | 公開日 | 2022-07-13 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
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7SYT
| Structure of the wt IRES w/o eIF2 48S initiation complex, closed conformation. Structure 13(wt) | 分子名称: | 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2021-11-25 | 公開日 | 2022-07-13 | 最終更新日 | 2023-02-01 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES. Embo J., 41, 2022
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7SYH
| Structure of the HCV IRES binding to the 40S ribosomal subunit, closed conformation. Structure 2(delta dII) | 分子名称: | 18S rRNA, 40S ribosomal protein S21, 40S ribosomal protein S24, ... | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | 登録日 | 2021-11-25 | 公開日 | 2022-07-13 | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | 主引用文献 | Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA To Be Published
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