8Q3J
| Crystal structure of mIL-38 in complex with a neutralizing Fab e04 fragment | 分子名称: | Fab e04 Heavy Chain (e04 HC), Fab e04 Light Chain (e04 LC), Interleukin-1 family member 10, ... | 著者 | Garcia-Pardo, J, Da Silva, P, Mora, J, Wiechmann, S, Putyrski, M, You, X, Kannt, A, Ernst, A, Brune, B, Weigert, A. | 登録日 | 2023-08-04 | 公開日 | 2024-08-14 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Neutralizing IL-38 activates gammaDelta T cell-dependent anti-tumor immunity and sensitizes for chemotherapy To be published
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5MRV
| Crystal structure of human carboxypeptidase O in complex with NvCI | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Carboxypeptidase O, Metallocarboxypeptidase inhibitor, ... | 著者 | Garcia-Pardo, J, Garcia-Guerrero, M.C, Fernandez-Alvarez, R, Lyons, P, Aviles, F.X, Lorenzo, J, Reverter, D. | 登録日 | 2016-12-27 | 公開日 | 2018-01-17 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.854 Å) | 主引用文献 | Crystal structure and mechanism of human carboxypeptidase O: Insights into its specific activity for acidic residues. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5AQ0
| The structure of the Transthyretin-like domain of the first catalytic domain of the HUMAN Carboxypeptidase D | 分子名称: | CARBOXYPEPTIDASE D, GLYCEROL | 著者 | Gallego, P, Garcia-Pardo, J, Lorenzo, J, Aviles, F.X, Ventura, S, Reverter, D. | 登録日 | 2015-09-18 | 公開日 | 2016-09-28 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | 主引用文献 | The Structure of the Ttldomain of the Human Carboxypeptidase D To be Published
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7ZIR
| Cryo-EM structure of hnRNPDL amyloid fibrils | 分子名称: | Heterogeneous nuclear ribonucleoprotein D-like | 著者 | Garcia-Pardo, J, Chaves-Sanjuan, A, Bartolome-Nafria, A, Gil-Garcia, M, Visentin, C, Bolognesi, M, Ricagno, S, Ventura, S. | 登録日 | 2022-04-08 | 公開日 | 2022-12-28 | 最終更新日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Cryo-EM structure of hnRNPDL-2 fibrils, a functional amyloid associated with limb-girdle muscular dystrophy D3. Nat Commun, 14, 2023
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6XX0
| Crystal structure of NEMO in complex with Ubv-LIN | 分子名称: | Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, isoform CRA_b, ... | 著者 | Akutsu, M, Skenderovic, A, Garcia-Pardo, J, Maculins, T, Dikic, I. | 登録日 | 2020-01-26 | 公開日 | 2021-02-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms. Cell Chem Biol, 27, 2020
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6YEK
| Crystal structure of human NEMO apo form | 分子名称: | Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma, isoform CRA_b | 著者 | Garcia-Pardo, J, Akutsu, M, Busse, P, Skenderovic, A, Maculins, T, Dikic, I. | 登録日 | 2020-03-25 | 公開日 | 2021-03-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Discovery of Protein-Protein Interaction Inhibitors by Integrating Protein Engineering and Chemical Screening Platforms. Cell Chem Biol, 27, 2020
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8PE2
| Crystal structure of Gel4 in complex with Nanobody 3 | 分子名称: | 1,3-beta-glucanosyltransferase, 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody 3, ... | 著者 | Macias-Leon, J, Redrado-Hernandez, S, Castro-Lopez, J, Sanz, A.B, Arias, M, Farkas, V, Vincke, C, Muyldermans, S, Pardo, J, Arroyo, J, Galvez, E, Hurtado-Guerrero, R. | 登録日 | 2023-06-13 | 公開日 | 2024-06-19 | 最終更新日 | 2024-07-31 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Broad Protection against Invasive Fungal Disease from a Nanobody Targeting the Active Site of Fungal beta-1,3-Glucanosyltransferases. Angew.Chem.Int.Ed.Engl., 2024
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8PE1
| Crystal structure of Gel4 in complex with Nanobody 4 | 分子名称: | 1,3-beta-glucanosyltransferase, 2-acetamido-2-deoxy-beta-D-glucopyranose, Nanobody 4, ... | 著者 | Macias-Leon, J, Redrado-Hernandez, S, Castro-Lopez, J, Sanz, A.B, Arias, M, Farkas, V, Vincke, C, Muyldermans, S, Pardo, J, Arroyo, J, Galvez, E, Hurtado-Guerrero, R. | 登録日 | 2023-06-13 | 公開日 | 2024-06-19 | 最終更新日 | 2024-07-31 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Broad Protection against Invasive Fungal Disease from a Nanobody Targeting the Active Site of Fungal beta-1,3-Glucanosyltransferases. Angew.Chem.Int.Ed.Engl., 2024
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