7OLE
 
 | | Cryo-EM structure of the TELO2-TTI1-TTI2-RUVBL1-RUVBL2 complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, RuvB-like 1, RuvB-like 2, ... | | 著者 | Pal, M, Llorca, O, Pearl, L. | | 登録日 | 2021-05-19 | | 公開日 | 2021-07-07 | | 最終更新日 | 2021-10-06 | | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | | 主引用文献 | Structure of the TELO2-TTI1-TTI2 complex and its function in TOR recruitment to the R2TP chaperone.
Cell Rep, 36, 2021
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6FM8
 | | RPAP3 c-terminus | | 分子名称: | RNA polymerase II-associated protein 3 | | 著者 | Pal, M, Roe, S.M. | | 登録日 | 2018-01-30 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | RPAP3 provides a flexible scaffold for coupling HSP90 to the human R2TP co-chaperone complex
Nat Commun, 2020
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3NFT
 | | Near-atomic resolution analysis of BipD- A component of the type-III secretion system of Burkholderia pseudomallei | | 分子名称: | Translocator protein bipD | | 著者 | Pal, M, Erskine, P.T, Gill, R.S, Wood, S.P, Cooper, J.B. | | 登録日 | 2010-06-10 | | 公開日 | 2010-07-14 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Near-atomic resolution analysis of BipD, a component of the type III secretion system of Burkholderia pseudomallei.
Acta Crystallogr.,Sect.F, 66, 2010
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5KKV
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8VCA
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6X24
 | | Structural basis of plant blue light photoreceptor | | 分子名称: | Cryptochrome-2, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL | | 著者 | Palayam, M, Ganapathy, J, Guercio, M.A, Shabek, N. | | 登録日 | 2020-05-19 | | 公開日 | 2020-12-16 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Structural insights into photoactivation of plant Cryptochrome-2.
Commun Biol, 4, 2021
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5HHD
 | | Crystal Structure of Chemically Synthesized Heterochiral {RFX037 plus VEGF-A} Protein Complex in space group P21 | | 分子名称: | D-Peptide RFX037.D, D-Vascular endothelial growth factor, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Uppalapati, M, LEE, D.J, Mandal, K, Kent, S.B.H, Sidhu, S. | | 登録日 | 2016-01-10 | | 公開日 | 2016-03-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A Potent d-Protein Antagonist of VEGF-A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo.
Acs Chem.Biol., 11, 2016
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8VCE
 | | Crystal Structure of plant Carboxylesterase 20 | | 分子名称: | 1,2-ETHANEDIOL, IMIDAZOLE, Probable carboxylesterase 120 | | 著者 | Palayam, M, Shabek, N. | | 登録日 | 2023-12-14 | | 公開日 | 2024-08-07 | | 最終更新日 | 2024-08-14 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural insights into strigolactone catabolism by carboxylesterases reveal a conserved conformational regulation.
Nat Commun, 15, 2024
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8VCD
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5WVX
 | | Crystal Structure of bifunctional Kunitz type Trypsin /amylase inhibitor (AMTIN) from the tubers of Alocasia macrorrhiza | | 分子名称: | 2-acetamido-2-deoxy-beta-D-galactopyranose, CITRIC ACID, Trypsin/chymotrypsin inhibitor | | 著者 | Palayam, M, Radhakrishnan, M, Lakshminarayanan, K, Balu, K.E, Ganapathy, J, Krishnasamy, G. | | 登録日 | 2016-12-29 | | 公開日 | 2018-06-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.003 Å) | | 主引用文献 | Structural insights into a multifunctional inhibitor, 'AMTIN' from tubers of Alocasia macrorrhizos and its possible role in dengue protease (NS2B-NS3) inhibition.
Int. J. Biol. Macromol., 113, 2018
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5HHC
 | | Crystal Structure of Chemically Synthesized Heterochiral {RFX037 plus VEGF-A} Protein Complex in space group P21/n | | 分子名称: | D- Vascular endothelial growth factor-A, GLYCEROL, Vascular endothelial growth factor A | | 著者 | Uppalapati, M, Lee, D.J, Mandal, K, Kent, S.B.H, Sidhu, S. | | 登録日 | 2016-01-10 | | 公開日 | 2016-03-09 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | A Potent d-Protein Antagonist of VEGF-A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo.
Acs Chem.Biol., 11, 2016
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7EH3
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4CGU
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4CGV
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4CGW
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4CHH
 | | N-terminal domain of yeast PIH1p | | 分子名称: | 1,2-ETHANEDIOL, PROTEIN INTERACTING WITH HSP90 1 | | 著者 | Roe, S.M, Pal, M. | | 登録日 | 2013-12-02 | | 公開日 | 2014-05-14 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2.03 Å) | | 主引用文献 | Structural Basis for Phosphorylation-Dependent Recruitment of Tel2 to Hsp90 by Pih1.
Structure, 22, 2014
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7SA1
 | | LRR-F-Box plant ubiquitin ligase | | 分子名称: | CITRIC ACID, DI(HYDROXYETHYL)ETHER, F-box/LRR-repeat MAX2 homolog, ... | | 著者 | Palayam, M, Shabek, N. | | 登録日 | 2021-09-21 | | 公開日 | 2022-04-20 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | | 主引用文献 | A conformational switch in the SCF-D3/MAX2 ubiquitin ligase facilitates strigolactone signalling.
Nat.Plants, 8, 2022
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7UPV
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4CGQ
 | | Full length Tah1 bound to HSP90 peptide SRMEEVD | | 分子名称: | CHLORIDE ION, HEAT SHOCK PROTEIN HSP 90-ALPHA, TPR REPEAT-CONTAINING PROTEIN ASSOCIATED WITH HSP90 | | 著者 | Roe, S.M, Pal, M. | | 登録日 | 2013-11-26 | | 公開日 | 2014-12-17 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Tah1 Helix-Swap Dimerization Prevents Mixed Hsp90 Co-Chaperone Complexes
Acta Crystallogr.,Sect.F, 71, 2015
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1I7N
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1I7L
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4WGI
 | | A Single Diastereomer of a Macrolactam Core Binds Specifically to Myeloid Cell Leukemia 1 (MCL1) | | 分子名称: | (2S)-2-[(2S,3R)-10-{[(4-fluorophenyl)sulfonyl]amino}-3-methyl-2-[(methyl{[4-(trifluoromethyl)phenyl]carbamoyl}amino)methyl]-6-oxo-3,4-dihydro-2H-1,5-benzoxazocin-5(6H)-yl]propanoic acid, FORMIC ACID, MAGNESIUM ION, ... | | 著者 | Clifton, M.C, Fairman, J.W, Fang, C, D'Souza, B, Fulroth, B, Leed, A, McCarren, P, Wang, L, Wang, Y, Kaushik, V, Palmer, M, Wei, G, Golub, T.R, Hubbard, B.K, Serrano-Wu, M.H. | | 登録日 | 2014-09-18 | | 公開日 | 2014-11-19 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Single Diastereomer of a Macrolactam Core Binds Specifically to Myeloid Cell Leukemia 1 (MCL1).
Acs Med.Chem.Lett., 5, 2014
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5BNG
 | | monomer of TALE type homeobox transcription factor MEIS1 complexes with specific DNA | | 分子名称: | DNA (5'-D(P*AP*AP*TP*TP*AP*GP*CP*TP*GP*TP*CP*A)-3'), DNA (5'-D(P*TP*GP*AP*CP*AP*GP*CP*TP*AP*A)-3'), DNA (5'-D(P*TP*GP*AP*CP*AP*GP*CP*TP*AP*A-3'), ... | | 著者 | Morgunova, E, Jolma, A, Yin, Y, Nitta, K, Dave, K, Popov, A, Taipale, M, Enge, M, Kivioja, T, Taipale, J. | | 登録日 | 2015-05-26 | | 公開日 | 2015-11-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | DNA-dependent formation of transcription factor pairs alters their binding specificity.
Nature, 527, 2015
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3OB6
 | | Structure of AdiC(N101A) in the open-to-out Arg+ bound conformation | | 分子名称: | ARGININE, AdiC arginine:agmatine antiporter | | 著者 | Carpena, X, Kowalczyk, L, Ratera, M, Valencia, E, Vazquez-lbar, J.L, Fita, I, Palacin, M. | | 登録日 | 2010-08-06 | | 公開日 | 2011-03-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Molecular basis of substrate-induced permeation by an amino acid antiporter.
Proc.Natl.Acad.Sci.USA, 108, 2011
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1C4O
 | | CRYSTAL STRUCTURE OF THE DNA NUCLEOTIDE EXCISION REPAIR ENZYME UVRB FROM THERMUS THERMOPHILUS | | 分子名称: | DNA NUCLEOTIDE EXCISION REPAIR ENZYME UVRB, SULFATE ION, octyl beta-D-glucopyranoside | | 著者 | Machius, M, Henry, L, Palnitkar, M, Deisenhofer, J. | | 登録日 | 1999-09-14 | | 公開日 | 2000-07-26 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal structure of the DNA nucleotide excision repair enzyme UvrB from Thermus thermophilus.
Proc.Natl.Acad.Sci.USA, 96, 1999
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