1LTH
 
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1LLD
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7X5F
 | | Nrf2-MafG heterodimer bound with CsMBE2 | | 分子名称: | Nuclear factor erythroid 2-related factor 2, Synthetic DNA, Transcription factor MafG | | 著者 | Sengoku, T, Shiina, M, Suzuki, K, Hamada, K, Sato, K, Uchiyama, A, Okada, C, Baba, S, Ohta, T, Motohashi, H, Yamamoto, M, Ogata, K. | | 登録日 | 2022-03-04 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis of transcription regulation by CNC family transcription factor, Nrf2.
Nucleic Acids Res., 50, 2022
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7X5G
 | | Nrf2 (A510Y)-MafG heterodimer bound with CsMBE2 | | 分子名称: | DNA (5'-D(*CP*AP*CP*AP*GP*TP*GP*AP*CP*TP*CP*AP*GP*CP*AP*G)-3'), DNA (5'-D(*GP*CP*TP*GP*CP*TP*GP*AP*GP*TP*CP*AP*CP*TP*GP*T)-3'), Nuclear factor erythroid 2-related factor 2, ... | | 著者 | Sengoku, T, Shiina, M, Suzuki, K, Hamada, K, Sato, K, Uchiyama, A, Okada, C, Baba, S, Ohta, T, Motohashi, H, Yamamoto, M, Ogata, K. | | 登録日 | 2022-03-04 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis of transcription regulation by CNC family transcription factor, Nrf2.
Nucleic Acids Res., 50, 2022
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7X5E
 | | Nrf2-MafG heterodimer bound with CsMBE1 | | 分子名称: | DNA (5'-D(*CP*AP*TP*GP*AP*TP*GP*AP*GP*TP*CP*AP*GP*CP*AP*A)-3'), DNA (5'-D(*GP*TP*TP*GP*CP*TP*GP*AP*CP*TP*CP*AP*TP*CP*AP*T)-3'), HEXAETHYLENE GLYCOL, ... | | 著者 | Sengoku, T, Shiina, M, Suzuki, K, Hamada, K, Sato, K, Uchiyama, A, Okada, C, Baba, S, Ohta, T, Motohashi, H, Yamamoto, M, Ogata, K. | | 登録日 | 2022-03-04 | | 公開日 | 2022-11-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural basis of transcription regulation by CNC family transcription factor, Nrf2.
Nucleic Acids Res., 50, 2022
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3TK5
 | | Factor Xa in complex with D102-4380 | | 分子名称: | 4-{3-[(4-chlorophenyl)amino]-3-oxopropyl}-3-({[5-(propan-2-yl)-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl]carbonyl}amino)benzoic acid, CALCIUM ION, Factor X heavy chain, ... | | 著者 | Suzuki, M, Mochizuki, A, Nagata, T, Takano, H, Kanno, H, Kishida, M, Ohta, T. | | 登録日 | 2011-08-25 | | 公開日 | 2012-08-29 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Zwitter ionic potent durable orally active Factor Xa inhibitor.
To be Published
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3TK6
 | | factor Xa in complex with D46-5241 | | 分子名称: | CALCIUM ION, Factor X heavy chain, Factor X light chain, ... | | 著者 | Suzuki, M, Mochizuki, A, Nagata, T, Takano, H, Kanno, H, Kishida, M, Ohta, T. | | 登録日 | 2011-08-25 | | 公開日 | 2012-08-29 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Zwitter ionic potent durable orally active Factor Xa inhibitor.
To be Published
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3ST7
 | | Crystal Structure of capsular polysaccharide assembling protein CapF from staphylococcus aureus | | 分子名称: | Capsular polysaccharide synthesis enzyme Cap5F, GLYCEROL, ZINC ION | | 著者 | Miyafusa, T, Tanaka, Y, Kuroda, M, Yao, M, Watanabe, M, Ohta, T, Tanaka, I, Caaveiro, J.M.M, Tsumoto, K. | | 登録日 | 2011-07-09 | | 公開日 | 2012-02-15 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Crystal structure of the enzyme CapF of Staphylococcus aureus reveals a unique architecture composed of two functional domains.
Biochem.J., 443, 2012
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2DSO
 | | Crystal structure of D138N mutant of Drp35, a 35kDa drug responsive protein from Staphylococcus aureus | | 分子名称: | CALCIUM ION, Drp35, GLYCEROL | | 著者 | Tanaka, Y, Ohki, Y, Morikawa, K, Yao, M, Watanabe, N, Ohta, T, Tanaka, I. | | 登録日 | 2006-07-04 | | 公開日 | 2006-12-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural and Mutational Analyses of Drp35 from Staphylococcus aureus: A POSSIBLE MECHANISM FOR ITS LACTONASE ACTIVITY
J.Biol.Chem., 282, 2007
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2DG1
 | | Crystal structure of Drp35, a 35kDa drug responsive protein from Staphylococcus aureus, complexed with Ca2+ | | 分子名称: | CALCIUM ION, DrP35, GLYCEROL | | 著者 | Tanaka, Y, Ohki, Y, Morikawa, K, Yao, M, Watanabe, N, Ohta, T, Tanaka, I. | | 登録日 | 2006-03-07 | | 公開日 | 2006-12-12 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | | 主引用文献 | Structural and Mutational Analyses of Drp35 from Staphylococcus aureus: A POSSIBLE MECHANISM FOR ITS LACTONASE ACTIVITY
J.Biol.Chem., 282, 2007
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2DG0
 | | Crystal structure of Drp35, a 35kDa drug responsive protein from Staphylococcus aureus | | 分子名称: | DrP35 | | 著者 | Tanaka, Y, Ohki, Y, Morikawa, K, Yao, M, Watanabe, N, Ohta, T, Tanaka, I. | | 登録日 | 2006-03-07 | | 公開日 | 2006-12-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural and Mutational Analyses of Drp35 from Staphylococcus aureus: A POSSIBLE MECHANISM FOR ITS LACTONASE ACTIVITY
J.Biol.Chem., 282, 2007
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2DGJ
 | | Crystal structure of EbhA (756-1003 domain) from Staphylococcus aureus | | 分子名称: | ACETIC ACID, GLYCEROL, SULFATE ION, ... | | 著者 | Tanaka, Y, Yao, M, Kuroda, M, Watanabe, N, Ohta, T, Tanaka, I. | | 登録日 | 2006-03-14 | | 公開日 | 2007-03-20 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | A helical string of alternately connected three-helix bundles for the cell wall-associated adhesion protein Ebh from Staphylococcus aureus
Structure, 16, 2008
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1X2J
 | | Structural basis for the defects of human lung cancer somatic mutations in the repression activity of Keap1 on Nrf2 | | 分子名称: | Kelch-like ECH-associated protein 1, SULFATE ION | | 著者 | Padmanabhan, B, Tong, K.I, Nakamura, Y, Ohta, T, Scharlock, M, Kobayashi, A, Ohtsuji, M, Kang, M.-I, Yamamoto, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-04-25 | | 公開日 | 2006-03-07 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural basis for defects of keap1 activity provoked by its point mutations in lung cancer
Mol.Cell, 21, 2006
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1X2R
 | | Structural basis for the defects of human lung cancer somatic mutations in the repression activity of Keap1 on Nrf2 | | 分子名称: | Kelch-like ECH-associated protein 1, Nuclear factor erythroid 2 related factor 2, SULFATE ION | | 著者 | Padmanabhan, B, Tong, K.I, Nakamura, Y, Ohta, T, Scharlock, M, Kobayashi, A, Ohtsuji, M, Kang, M.-I, Yamamoto, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-04-26 | | 公開日 | 2006-03-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural basis for defects of keap1 activity provoked by its point mutations in lung cancer
Mol.Cell, 21, 2006
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1GEA
 | | RECEPTOR-BOUND CONFORMATION OF PACAP21 | | 分子名称: | PITUITARY ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE | | 著者 | Inooka, H, Ohtaki, T, Kitahara, O, Ikegami, T, Endo, S, Kitada, C, Ogi, K, Onda, H, Fujino, M, Shirakawa, M. | | 登録日 | 2000-10-20 | | 公開日 | 2001-04-20 | | 最終更新日 | 2023-12-27 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Conformation of a peptide ligand bound to its G-protein coupled receptor.
Nat.Struct.Biol., 8, 2001
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4DZT
 | | Aqualysin I: the crystal structure of a serine protease from an extreme thermophile, Thermus aquaticus YT-1 | | 分子名称: | Aqualysin-1, CALCIUM ION, phenylmethanesulfonic acid | | 著者 | Barnett, B.L, Green, P.R, Strickland, L.C, Oliver, J.D, Rydel, T, Sullivan, J.F. | | 登録日 | 2012-03-01 | | 公開日 | 2012-03-28 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Aqualysin I: the crystal structure of a serine protease from an extreme thermophile, Thermus aquaticus YT-1
To be Published
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7RGW
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2RR2
 | | Structure of O-fucosylated epidermal growth factor-like repeat 12 of mouse Notch-1 receptor | | 分子名称: | Neurogenic locus notch homolog protein 1, alpha-L-fucopyranose | | 著者 | Hosoguchi, K, Shimizu, K, Fujitani, N, Nishimura, S. | | 登録日 | 2010-02-26 | | 公開日 | 2010-10-13 | | 最終更新日 | 2020-07-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Chemical Synthesis, Folding, and Structural Insights into O-Fucosylated Epidermal Growth Factor-like Repeat 12 of Mouse Notch-1 Receptor
J.Am.Chem.Soc., 132, 2010
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2RR0
 | | Structure of epidermal growth factor-like repeat 12 of mouse Notch-1 receptor | | 分子名称: | Neurogenic locus notch homolog protein 1 | | 著者 | Hosoguchi, K, Shimizu, K, Fujitani, N, Nishimura, S. | | 登録日 | 2010-02-26 | | 公開日 | 2010-10-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Chemical Synthesis, Folding, and Structural Insights into O-Fucosylated Epidermal Growth Factor-like Repeat 12 of Mouse Notch-1 Receptor
J.Am.Chem.Soc., 132, 2010
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2RQZ
 | | Structure of sugar modified epidermal growth factor-like repeat 12 of mouse Notch-1 receptor | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-alpha-L-fucopyranose, Neurogenic locus notch homolog protein 1 | | 著者 | Shimizu, K, Fujitani, N, Hosoguchi, K, Nishimura, S. | | 登録日 | 2010-02-26 | | 公開日 | 2010-10-13 | | 最終更新日 | 2020-07-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Chemical Synthesis, Folding, and Structural Insights into O-Fucosylated Epidermal Growth Factor-like Repeat 12 of Mouse Notch-1 Receptor
J.Am.Chem.Soc., 132, 2010
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3IIT
 | | Factor XA in complex with a cis-1,2-diaminocyclohexane derivative | | 分子名称: | 7-chloro-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-{[(5-methyl-5,6-dihydro-4H-pyrrolo[3,4-d][1,3]thiazol-2-yl)carbonyl]amino}cyclohexyl]isoquinoline-3-carboxamide, Activated factor Xa heavy chain, CALCIUM ION, ... | | 著者 | Suzuki, M. | | 登録日 | 2009-08-03 | | 公開日 | 2010-08-04 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part II: exploration of 6-6 fused rings as alternative S1 moieties.
Bioorg.Med.Chem., 17, 2009
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3Q3K
 | | Factor Xa in complex with a phenylenediamine derivative | | 分子名称: | Activated factor Xa heavy chain, CALCIUM ION, Factor X light chain, ... | | 著者 | Suzuki, M, Imai, E. | | 登録日 | 2010-12-22 | | 公開日 | 2011-12-28 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Design, synthesis and SAR of novel ethylenediamine and phenylenediamine derivatives as factor Xa inhibitors.
Bioorg.Med.Chem.Lett., 21, 2011
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2E7A
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1EZ4
 | | CRYSTAL STRUCTURE OF NON-ALLOSTERIC L-LACTATE DEHYDROGENASE FROM LACTOBACILLUS PENTOSUS AT 2.3 ANGSTROM RESOLUTION | | 分子名称: | LACTATE DEHYDROGENASE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Uchikoba, H, Fushinobu, S, Wakagi, T, Konno, M, Taguchi, H, Matsuzawa, H. | | 登録日 | 2000-05-10 | | 公開日 | 2001-12-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of non-allosteric L-lactate dehydrogenase from Lactobacillus pentosus at 2.3 A resolution: specific interactions at subunit interfaces.
Proteins, 46, 2002
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3IS1
 | | Crystal structure of functional region of UafA from Staphylococcus saprophyticus in C2 form at 2.45 angstrom resolution | | 分子名称: | GLYCEROL, Uro-adherence factor A | | 著者 | Tanaka, Y, Matsuoka, E, Shouji, Y, Kuroda, M, Tanaka, I, Yao, M. | | 登録日 | 2009-08-24 | | 公開日 | 2010-09-08 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Crystal structure of the functional region of Uro-adherence factor A from Staphylococcus saprophyticus reveals participation of the B domain in ligand binding
Protein Sci., 20, 2011
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