8IYU
 
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8I55
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8I56
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8I58
 | | Uroporphyrin I (UPI)-bound CfbA | | 分子名称: | 3-[(1Z,9Z)-3,8,13,18-tetrakis(2-hydroxy-2-oxoethyl)-7,12,17-tris(3-hydroxy-3-oxopropyl)-21,23-dihydroporphyrin-2-yl]propanoic acid, Sirohydrochlorin cobaltochelatase | | 著者 | Ogawa, S, Fujishiro, T. | | 登録日 | 2023-01-24 | | 公開日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | | 主引用文献 | Substrate selectivity of CfbA
To be published
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8I57
 | | Uroporphyrin III (UPIII)-bound CfbA | | 分子名称: | 3,3',3'',3'''-[3,8,13,17-tetrakis(carboxymethyl)porphyrin-2,7,12,18-tetrayl]tetrapropanoic acid, Sirohydrochlorin cobaltochelatase | | 著者 | Ogawa, S, Fujishiro, T. | | 登録日 | 2023-01-24 | | 公開日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | | 主引用文献 | Substrate selectivity of CfbA
To be published
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2RPS
 | | Solution structure of a novel insect chemokine isolated from integument | | 分子名称: | Chemokine | | 著者 | Kamiya, M, Nakatogawa, S, Oda, Y, Kamijima, T, Aizawa, T, Demura, M, Hayakawa, Y, Kawano, K. | | 登録日 | 2008-07-28 | | 公開日 | 2009-06-16 | | 最終更新日 | 2022-03-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A novel peptide mediates aggregation and migration of hemocytes from an insect
Curr.Biol., 19, 2009
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5GJI
 | | PI3K p85 N-terminal SH2 domain/CD28-derived peptide complex | | 分子名称: | GLYCEROL, Phosphatidylinositol 3-kinase regulatory subunit alpha, SULFATE ION, ... | | 著者 | Inaba, S, Numoto, N, Morii, H, Ogawa, S, Ikura, T, Abe, R, Ito, N, Oda, M. | | 登録日 | 2016-06-30 | | 公開日 | 2016-12-14 | | 最終更新日 | 2017-05-10 | | 実験手法 | X-RAY DIFFRACTION (0.9 Å) | | 主引用文献 | Crystal Structures and Thermodynamic Analysis Reveal Distinct Mechanisms of CD28 Phosphopeptide Binding to the Src Homology 2 (SH2) Domains of Three Adaptor Proteins
J. Biol. Chem., 292, 2017
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5GJH
 | | Gads SH2 domain/CD28-derived peptide complex | | 分子名称: | GRB2-related adapter protein 2, T-cell-specific surface glycoprotein CD28 | | 著者 | Inaba, S, Numoto, N, Morii, H, Ogawa, S, Ikura, T, Abe, R, Ito, N, Oda, M. | | 登録日 | 2016-06-30 | | 公開日 | 2016-12-14 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Crystal Structures and Thermodynamic Analysis Reveal Distinct Mechanisms of CD28 Phosphopeptide Binding to the Src Homology 2 (SH2) Domains of Three Adaptor Proteins
J. Biol. Chem., 292, 2017
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6ICG
 | | Grb2 SH2 domain in phosphopeptide free form | | 分子名称: | GLYCEROL, Growth factor receptor-bound protein 2, SULFATE ION | | 著者 | Hosoe, Y, Numoto, N, Inaba, S, Ogawa, S, Morii, H, Abe, R, Ito, N, Oda, M. | | 登録日 | 2018-09-06 | | 公開日 | 2019-07-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | | 主引用文献 | Structural and functional properties of Grb2 SH2 dimer in CD28 binding.
Biophys Physicobio., 16, 2019
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6ICH
 | | Grb2 SH2 domain in domain swapped dimer form | | 分子名称: | Growth factor receptor-bound protein 2 | | 著者 | Hosoe, Y, Numoto, N, Inaba, S, Ogawa, S, Morii, H, Abe, R, Ito, N, Oda, M. | | 登録日 | 2018-09-06 | | 公開日 | 2019-07-17 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural and functional properties of Grb2 SH2 dimer in CD28 binding.
Biophys Physicobio., 16, 2019
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7CIO
 | | Molecular interactions of cytoplasmic region of CTLA-4 with SH2 domains of PI3-kinase | | 分子名称: | Cytotoxic T-lymphocyte protein 4, Phosphatidylinositol 3-kinase regulatory subunit alpha | | 著者 | Iiyama, M, Numoto, N, Ogawa, S, Kuroda, M, Morii, H, Abe, R, Ito, N, Oda, M. | | 登録日 | 2020-07-08 | | 公開日 | 2020-12-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Molecular interactions of the CTLA-4 cytoplasmic region with the phosphoinositide 3-kinase SH2 domains.
Mol.Immunol., 131, 2021
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6M28
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6M2H
 | | A reaction intermediate of sirohydrochlorin nickelochelatase CfbA in complex with Ni2+ and sirohydrochlorin | | 分子名称: | 3,3',3'',3'''-[(7S,8S,12S,13S)-3,8,13,17-tetrakis(carboxymethyl)-8,13-dimethyl-7,8,12,13-tetrahydroporphyrin-2,7,12,18-tetrayl]tetrapropanoic acid, NICKEL (II) ION, Sirohydrochlorin cobaltochelatase | | 著者 | Fujishiro, T. | | 登録日 | 2020-02-27 | | 公開日 | 2021-01-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | The nickel-sirohydrochlorin formation mechanism of the ancestral class II chelatase CfbA in coenzyme F430 biosynthesis.
Chem Sci, 12, 2021
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4QCI
 | | PDGF-B blocking antibody bound to PDGF-BB | | 分子名称: | Platelet-derived growth factor subunit B, anti-PDGF-BB antibody - Light Chain, anti-PDGF-BB antibody - Heavy chain | | 著者 | Kuai, J, Mosyak, L, Tam, M, LaVallie, E, Pullen, N, Carven, G. | | 登録日 | 2014-05-12 | | 公開日 | 2015-03-11 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Characterization of Binding Mode of Action of a Blocking Anti-Platelet-Derived Growth Factor (PDGF)-B Monoclonal Antibody, MOR8457, Reveals Conformational Flexibility and Avidity Needed for PDGF-BB To Bind PDGF Receptor-beta.
Biochemistry, 54, 2015
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6M2G
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6M26
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6M29
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6M25
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6M27
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6M2A
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6M2E
 | | Sirohydrochlorin nickelochelatase CfbA in complex with sirohydrochlorin | | 分子名称: | 3,3',3'',3'''-[(7S,8S,12S,13S)-3,8,13,17-tetrakis(carboxymethyl)-8,13-dimethyl-7,8,12,13-tetrahydroporphyrin-2,7,12,18-tetrayl]tetrapropanoic acid, Sirohydrochlorin cobaltochelatase | | 著者 | Fujishiro, T. | | 登録日 | 2020-02-27 | | 公開日 | 2021-01-13 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | The nickel-sirohydrochlorin formation mechanism of the ancestral class II chelatase CfbA in coenzyme F430 biosynthesis.
Chem Sci, 12, 2021
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6M2F
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5ZSK
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5ZSP
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5ZSO
 | | SufS from Bacillus subtilis, soaked with L-cysteine for 90 sec | | 分子名称: | Cysteine desulfurase SufS, DI(HYDROXYETHYL)ETHER, N-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)-L-CYSTEINE | | 著者 | Nakamura, R, Fujishiro, T, Takahashi, Y. | | 登録日 | 2018-04-29 | | 公開日 | 2019-05-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Snapshots of PLP-substrate and PLP-product external aldimines as intermediates in two types of cysteine desulfurase enzymes.
Febs J., 287, 2020
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