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4WNO
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BU of 4wno by Molmil
Structure of ULK1 bound to an inhibitor
分子名称: N~2~-(4-aminophenyl)-N~4~-(5-cyclopropyl-1H-pyrazol-3-yl)quinazoline-2,4-diamine, Serine/threonine-protein kinase ULK1
著者Lazarus, M.B, Novotny, C.J, Shokat, K.M.
登録日2014-10-14
公開日2015-01-14
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Structure of the Human Autophagy Initiating Kinase ULK1 in Complex with Potent Inhibitors.
Acs Chem.Biol., 10, 2015
4WNP
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BU of 4wnp by Molmil
Structure of ULK1 bound to a potent inhibitor
分子名称: GLYCEROL, N~2~-(1H-benzimidazol-6-yl)-N~4~-(5-cyclobutyl-1H-pyrazol-3-yl)quinazoline-2,4-diamine, Serine/threonine-protein kinase ULK1
著者Lazarus, M.B, Novotny, C.J, Shokat, K.M.
登録日2014-10-14
公開日2015-01-14
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structure of the Human Autophagy Initiating Kinase ULK1 in Complex with Potent Inhibitors.
Acs Chem.Biol., 10, 2015
5JEB
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BU of 5jeb by Molmil
Crystal structure of EGFR tyrosine kinase domain with novel inhibitor of active state of HER2
分子名称: 3-(furan-2-yl)-N-[5-(furan-2-yl)-2-methoxyphenyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Epidermal growth factor receptor, SULFATE ION
著者Park, J.H, Lemmon, M.A.
登録日2016-04-18
公開日2016-09-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.298 Å)
主引用文献Overcoming resistance to HER2 inhibitors through state-specific kinase binding.
Nat.Chem.Biol., 12, 2016

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件を2024-07-31に公開中

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