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7YV9
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Cryo-EM structure of full-length Myosin Va in the autoinhibited state
分子名称: Calmodulin-1, Unconventional myosin-Va
著者Niu, F, Wei, Z.
登録日2022-08-19
公開日2022-12-21
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (4.78 Å)
主引用文献Autoinhibition and activation mechanisms revealed by the triangular-shaped structure of myosin Va.
Sci Adv, 8, 2022
8W41
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Cryo-EM structure of Myosin VI in the autoinhibited state
分子名称: ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Calmodulin-1, ...
著者Niu, F, Wei, Z.
登録日2023-08-23
公開日2024-02-21
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Autoinhibition and activation of myosin VI revealed by its cryo-EM structure.
Nat Commun, 15, 2024
4M4E
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TRAF domain of human TRAF4
分子名称: TNF receptor-associated factor 4
著者Niu, F, Ru, H, Ding, W, Ouyang, S, Liu, Z.J.
登録日2013-08-07
公開日2013-09-11
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural biology study of human TNF receptor associated factor 4 TRAF domain
Protein Cell, 4, 2013
6KU0
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BU of 6ku0 by Molmil
Crystal structure of MyoVa-GTD in complex with MICAL1-GTBM
分子名称: 1,2-ETHANEDIOL, Peptide from [F-actin]-monooxygenase MICAL1, Unconventional myosin-Va
著者Niu, F, Wei, Z.
登録日2019-08-29
公開日2020-09-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献F-actin disassembly factor MICAL1 binding to Myosin Va mediates cargo unloading during cytokinesis.
Sci Adv, 6, 2020
4J1G
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BU of 4j1g by Molmil
Leanyer orthobunyavirus nucleoprotein-ssRNA complex
分子名称: Nucleocapsid, RNA (45-MER)
著者Niu, F, Shaw, N, Wang, Y, Jiao, L, Ding, W, Li, X, Zhu, P, Upur, H, Ouyang, S, Cheng, G, Liu, Z.J.
登録日2013-02-01
公開日2013-04-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.789 Å)
主引用文献Structure of the Leanyer orthobunyavirus nucleoprotein-RNA complex reveals unique architecture for RNA encapsidation.
Proc.Natl.Acad.Sci.USA, 110, 2013
4J1J
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Leanyer orthobunyavirus nucleoprotein-ssDNA complex
分子名称: DNA (5'-D(P*AP*CP*CP*AP*AP*AP*CP*AP*AP*CP*CP*CP*AP*CP*CP*CP*A)-3'), Nucleocapsid
著者Niu, F, Shaw, N, Wang, Y, Jiao, L, Ding, W, Li, X, Zhu, P, Upur, H, Ouyang, S, Cheng, G, Liu, Z.J.
登録日2013-02-01
公開日2013-04-10
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structure of the Leanyer orthobunyavirus nucleoprotein-RNA complex reveals unique architecture for RNA encapsidation.
Proc.Natl.Acad.Sci.USA, 110, 2013
8HLO
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BU of 8hlo by Molmil
Crystal structure of ASAP1-SH3 and MICAL1-PRM complex
分子名称: Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1, Proline rich motif from MICAL1, ...
著者Niu, F, Wei, Z, Yu, C.
登録日2022-11-30
公開日2023-02-22
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.168 Å)
主引用文献Crystal Structure of the SH3 Domain of ASAP1 in Complex with the Proline Rich Motif (PRM) of MICAL1 Reveals a Unique SH3/PRM Interaction Mode.
Int J Mol Sci, 24, 2023
4Y5U
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Transcription factor
分子名称: NICKEL (II) ION, Signal transducer and activator of transcription 6
著者Li, J, Niu, F, Ouyang, S, Liu, Z.
登録日2015-02-12
公開日2016-02-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.708 Å)
主引用文献Structural basis for DNA recognition by STAT6
Proc.Natl.Acad.Sci.USA, 113, 2016
4Y5W
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Transcription factor-DNA complex
分子名称: DNA (5'-D(P*AP*TP*GP*GP*AP*TP*TP*TP*CP*CP*TP*AP*GP*GP*AP*AP*GP*AP*CP*AP*A)-3'), DNA (5'-D(P*TP*TP*GP*TP*CP*TP*TP*CP*CP*TP*AP*GP*GP*AP*AP*AP*TP*CP*CP*AP*T)-3'), Signal transducer and activator of transcription 6
著者Li, J, Niu, F, Ouyang, S, Liu, Z.
登録日2015-02-12
公開日2016-02-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.104 Å)
主引用文献Structural basis for DNA recognition by STAT6
Proc.Natl.Acad.Sci.USA, 113, 2016
5BPJ
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BU of 5bpj by Molmil
All Three Ca(2+)-binding Loops of Light-sensitive Ctenophore Photoprotein Berovin Bind Magnesium Ions: The Spatial Structure of Mg(2+)-loaded Apo-berovin
分子名称: Apoberovin 1, MAGNESIUM ION
著者Burakova, L.P, Natashin, P.V, Malikova, N.P, Niu, F, Vysotski, E.S, Liu, Z.-J.
登録日2015-05-28
公開日2015-12-30
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.756 Å)
主引用文献All Ca(2+)-binding loops of light-sensitive ctenophore photoprotein berovin bind magnesium ions: The spatial structure of Mg(2+)-loaded apo-berovin.
J. Photochem. Photobiol. B, Biol., 154, 2016
5D39
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Transcription factor-DNA complex
分子名称: DNA (5'-D(P*AP*TP*GP*GP*AP*TP*TP*TP*CP*CP*TP*GP*GP*AP*AP*GP*AP*CP*AP*GP*A)-3'), DNA (5'-D(P*TP*CP*TP*GP*TP*CP*TP*TP*CP*CP*AP*GP*GP*AP*AP*AP*TP*CP*CP*AP*T)-3'), Signal transducer and activator of transcription 6
著者Li, J, Niu, F, Ouyang, S, Liu, Z.
登録日2015-08-06
公開日2016-08-10
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structural basis for DNA recognition by STAT6
Proc.Natl.Acad.Sci.USA, 113, 2016
4EF4
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BU of 4ef4 by Molmil
Crystal structure of STING CTD complex with c-di-GMP
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), CALCIUM ION, Transmembrane protein 173
著者Ouyang, S, Ru, H, Shaw, N, Jiang, Y, Niu, F, Zhu, Y, Qiu, W, Li, Y, Liu, Z.-J.
登録日2012-03-29
公開日2012-05-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.147 Å)
主引用文献Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding
Immunity, 36, 2012
4EF5
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BU of 4ef5 by Molmil
Crystal structure of STING CTD
分子名称: Transmembrane protein 173
著者Ouyang, S, Ru, H, Shaw, N, Jiang, Y, Niu, F, Zhu, Y, Qiu, W, Li, Y, Liu, Z.-J.
登録日2012-03-29
公開日2012-05-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding
Immunity, 36, 2012
4J4R
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BU of 4j4r by Molmil
Hexameric SFTSVN
分子名称: Nucleocapsid protein
著者Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
登録日2013-02-07
公開日2013-05-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4J4S
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Triple mutant SFTAVN
分子名称: Nucleocapsid protein, SODIUM ION
著者Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
登録日2013-02-07
公開日2013-05-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.442 Å)
主引用文献Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4J4V
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Pentameric SFTSVN with suramin
分子名称: 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, Nucleocapsid protein
著者Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
登録日2013-02-07
公開日2013-05-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.303 Å)
主引用文献Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4J4W
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BU of 4j4w by Molmil
Crystal structure of BueVN
分子名称: Nucleocapsid
著者Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
登録日2013-02-07
公開日2013-05-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.661 Å)
主引用文献Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4J4Y
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Triple mutant GraVN
分子名称: NP protein
著者Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
登録日2013-02-07
公開日2013-06-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4J4U
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BU of 4j4u by Molmil
Pentamer SFTSVN
分子名称: Nucleocapsid protein
著者Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
登録日2013-02-07
公開日2013-05-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.803 Å)
主引用文献Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
4J4X
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Crystal structure of GraVN
分子名称: NP protein
著者Jiao, L, Ouyang, S, Liang, M, Niu, F, Shaw, N, Wu, W, Ding, W, Jin, C, Zhu, Y, Zhang, F, Wang, T, Li, C, Zuo, X, Luan, C.H, Li, D, Liu, Z.J.
登録日2013-02-07
公開日2013-05-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structure of severe Fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential
J.Virol., 87, 2013
7YW5
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BU of 7yw5 by Molmil
Crystal Structure of the ITS1 processing by human ribonuclease ISG20L2 with mutation D327A
分子名称: Interferon-stimulated 20 kDa exonuclease-like 2
著者Yang, X.Y, Liu, X.H.
登録日2022-08-21
公開日2024-01-17
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献Molecular mechanism of human ISG20L2 for the ITS1 cleavage in the processing of 18S precursor ribosomal RNA.
Nucleic Acids Res., 52, 2024
7D2G
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Coiled-coil structure of liprin-alpha2_H2delC
分子名称: GLYCEROL, Liprin-alpha-2
著者Liang, M, Wei, Z.
登録日2020-09-16
公開日2021-04-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Oligomerized liprin-alpha promotes phase separation of ELKS for compartmentalization of presynaptic active zone proteins.
Cell Rep, 34, 2021
7D2E
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Tetrameric coiled-coil structure of liprin-alpha2_H3
分子名称: Liprin-alpha-2
著者Liang, M, Wei, Z.
登録日2020-09-16
公開日2021-04-07
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Oligomerized liprin-alpha promotes phase separation of ELKS for compartmentalization of presynaptic active zone proteins.
Cell Rep, 34, 2021
7D2H
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Tetrameric coiled-coil structure of liprin-alpha2_H2
分子名称: GLYCEROL, Liprin-alpha-2
著者Liang, M, Wei, Z.
登録日2020-09-16
公開日2021-04-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Oligomerized liprin-alpha promotes phase separation of ELKS for compartmentalization of presynaptic active zone proteins.
Cell Rep, 34, 2021
5VK0
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Crystal structure of human MDM2 in complex with a 12-mer lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI
分子名称: CHLORIDE ION, E3 ubiquitin-protein ligase Mdm2, Lysine-cysteine side chain dithiocarbamate stapled peptide inhibitor PMI
著者Tolbert, W.D, Gohain, N, Pazgier, M.
登録日2017-04-20
公開日2018-04-25
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Dithiocarbamate-inspired side chain stapling chemistry for peptide drug design.
Chem Sci, 10, 2019

 

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