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2OSB
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BU of 2osb by Molmil
Crystal structure of a thermostable mutant of Bacillus subtilis Adenylate Kinase (Q16L/Q199R/)
分子名称: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ...
著者Myers, J, Counago, R, Wilson, C.J, Wu, G, Shamoo, Y.
登録日2007-02-05
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a thermostable mutant of Bacillus subtilis Adenylate Kinase (Q16L/Q199R/)
To be Published
8FMA
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BU of 8fma by Molmil
Nodavirus RNA replication proto-crown, detergent-solubliized C11 multimer
分子名称: RNA-directed RNA polymerase
著者Zhan, H, Unchwaniwala, N, Rebolledo Viveros, A, Pennington, J, Horswill, M, Broadberry, R, Myers, J, den Boon, J, Grant, T, Ahlquist, P.
登録日2022-12-22
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FM9
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BU of 8fm9 by Molmil
Nodavirus RNA replication proto-crown, detergent-solubliized C12 multimer
分子名称: RNA-directed RNA polymerase
著者Zhan, H, Unchwaniwala, N, Rebolledo Viveros, A, Pennington, J, Horswill, M, Broadberry, R, Myers, J, den Boon, J, Grant, T, Ahlquist, P.
登録日2022-12-22
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching.
Proc.Natl.Acad.Sci.USA, 120, 2023
8FMB
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BU of 8fmb by Molmil
Nodavirus RNA replication protein A polymerase domain, local refinement
分子名称: RNA-directed RNA polymerase
著者Zhan, H, Unchwaniwala, N, Rebolledo Viveros, A, Pennington, J, Horswill, M, Broadberry, R, Myers, J, den Boon, J, Grant, T, Ahlquist, P.
登録日2022-12-22
公開日2023-02-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (6.3 Å)
主引用文献Nodavirus RNA replication crown architecture reveals proto-crown precursor and viral protein A conformational switching.
Proc.Natl.Acad.Sci.USA, 120, 2023
2QAJ
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BU of 2qaj by Molmil
Crystal structure of a thermostable mutant of Bacillus subtilis Adenylate Kinase (Q199R/G213E)
分子名称: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ...
著者Counago, R, Wilson, C.J, Myers, J, Wu, G, Shamoo, Y.
登録日2007-06-15
公開日2008-04-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a thermostable mutant of Bacillus subtilis Adenylate Kinase (Q199R/G213E)
To be Published
2OC8
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BU of 2oc8 by Molmil
Structure of Hepatitis C Viral NS3 protease domain complexed with NS4A peptide and ketoamide SCH503034
分子名称: BETA-MERCAPTOETHANOL, Hepatitis C virus, ZINC ION, ...
著者Prongay, A.J, Guo, Z, Yao, N, Fischmann, T, Strickland, C, Myers, J, Weber, P.C, Malcolm, B, Beyer, B.M, Ingram, R, Pichardo, J, Hong, Z, Prosise, W.W, Ramanathan, L, Taremi, S.S, Yarosh-Tomaine, T, Zhang, R, Senior, M, Yang, R.S, Arasappan, A, Bennett, F, Bogen, S.L, Chen, K, Jao, E, Liu, Y.T, Lovey, R.G, Saksena, A.K, Venkatraman, S, Girijavallabhan, V, Njoroge, F.G, Madison, V.
登録日2006-12-20
公開日2007-07-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Discovery of the HCV NS3/4A protease inhibitor (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]-3- [2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (Sch 503034) II. Key steps in structure-based optimization.
J.Med.Chem., 50, 2007
2ORI
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BU of 2ori by Molmil
Crystal structure of a thermostable mutant of Bacillus subtilis Adenylate Kinase (A193V/Q199R/)
分子名称: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ...
著者Counago, R, Shamoo, Y, Wilson, C.J, Wu, G, Myers, J.
登録日2007-02-02
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a thermostable mutant of Bacillus subtilis Adenylate Kinase (A193V/Q199R/)
To be Published
2P3S
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BU of 2p3s by Molmil
Crystal structure of a thermostable mutant of Bacillus subtilis Adenylate Kinase (G214R/Q199R)
分子名称: Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, MAGNESIUM ION, ...
著者Counago, R, Wilson, C.J, Myers, J, Wu, G, Shamoo, Y.
登録日2007-03-09
公開日2008-01-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of a thermostable mutant of Bacillus subtilis Adenylate Kinase (G214R/Q199R)
To be Published
5U6Y
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BU of 5u6y by Molmil
Pseudo-atomic model of the CaMKIIa holoenzyme.
分子名称: Calcium/calmodulin-dependent protein kinase type II subunit alpha
著者Myers, J, Reichow, S.L.
登録日2016-12-09
公開日2017-06-21
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (20 Å)
主引用文献The CaMKII holoenzyme structure in activation-competent conformations.
Nat Commun, 8, 2017
3TDE
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BU of 3tde by Molmil
Crystal structure of S-adenosylmethionine synthetase Rv1392 from Mycobacterium tuberculosis
分子名称: S-adenosylmethionine synthase, SODIUM ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-08-10
公開日2011-08-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3SWX
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BU of 3swx by Molmil
Crystal structure of a probable enoyl-CoA hydratase/isomerase from Mycobacterium abscessus
分子名称: 1,2-ETHANEDIOL, GLYCEROL, Probable enoyl-CoA hydratase/isomerase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-07-14
公開日2011-07-27
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3TCR
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BU of 3tcr by Molmil
Crystal structure of a molybdopterin biosynthesis protein from Mycobacterium abscessus
分子名称: Molybdopterin biosynthesis protein
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-08-09
公開日2011-08-24
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3TAV
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BU of 3tav by Molmil
Crystal structure of a Methionine Aminopeptidase from Mycobacterium abscessus
分子名称: (2S)-2-hydroxybutanedioic acid, CHLORIDE ION, D-MALATE, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-08-04
公開日2011-08-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4EYE
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BU of 4eye by Molmil
Crystal structure of a probable oxidoreductase from Mycobacterium abscessus solved by iodide ion SAD
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, IODIDE ION, Probable oxidoreductase
著者Edwards, T.E, Abendroth, J, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-05-01
公開日2012-05-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4EGF
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BU of 4egf by Molmil
Crystal structure of a L-xylulose reductase from Mycobacterium smegmatis
分子名称: L-xylulose reductase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID), Arakaki, T.L, Staker, B.L, Fairman, J.W.
登録日2012-03-30
公開日2012-05-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4EO9
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BU of 4eo9 by Molmil
Crystal structure of a phosphoglycerate mutase gpm1 from Mycobacterium leprae
分子名称: 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase, CHLORIDE ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-04-13
公開日2012-04-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4ED4
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BU of 4ed4 by Molmil
Crystal structure of IspE (4-diphosphocytidyl-2-C-methyl-D-erythritol kinase) from Mycobacterium abcessus, bound to ATP
分子名称: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, ADENOSINE-5'-TRIPHOSPHATE
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-03-26
公開日2012-04-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4EMD
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BU of 4emd by Molmil
Crystal structure of IspE (4-diphosphocytidyl-2-C-methyl-D-erythritol kinase) from Mycobacterium abcessus, bound to CMP and SO4
分子名称: 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, CYTIDINE-5'-MONOPHOSPHATE, SULFATE ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-04-11
公開日2012-04-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4EGE
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BU of 4ege by Molmil
Crystal Structure of Dipeptidase PepE from Mycobacterium ulcerans
分子名称: 1,2-ETHANEDIOL, Dipeptidase PepE, UNKNOWN ATOM OR ION, ...
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-03-30
公開日2012-04-25
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
3T7C
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BU of 3t7c by Molmil
Crystal structure of carveol dehydrogenase from Mycobacterium avium bound to NAD
分子名称: Carveol dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-07-29
公開日2011-08-17
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors.
Sci Rep, 7, 2017
4OV6
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BU of 4ov6 by Molmil
Crystal structure of PCSK9(53-451) with Adnectin
分子名称: 1,2-ETHANEDIOL, Adnectin, Proprotein convertase subtilisin/kexin type 9, ...
著者Khan, J.A.
登録日2014-02-20
公開日2014-07-02
最終更新日2017-11-22
実験手法X-RAY DIFFRACTION (2.69 Å)
主引用文献Pharmacologic Profile of the Adnectin BMS-962476, a Small Protein Biologic Alternative to PCSK9 Antibodies for Low-Density Lipoprotein Lowering.
J.Pharmacol.Exp.Ther., 350, 2014
4O2D
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BU of 4o2d by Molmil
Crystal structure of aspartyl-tRNA synthetase from Mycobacterium smegmatis with bound aspartic acid
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ASPARTIC ACID, Aspartate--tRNA ligase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2013-12-17
公開日2014-01-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4DI1
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BU of 4di1 by Molmil
Crystal structure of enoyl-CoA hydratase EchA17 from Mycobacterium marinum
分子名称: 1,2-ETHANEDIOL, Enoyl-CoA hydratase EchA17
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-01-30
公開日2012-02-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4DQ8
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BU of 4dq8 by Molmil
Crystal structure of acetate kinase AckA from Mycobacterium marinum
分子名称: Acetate kinase
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-02-15
公開日2012-02-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
4DIE
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BU of 4die by Molmil
Crystal structure of a cytidylate kinase CmK from Mycobacterium abscessus bound to cytidine-5'-monophosphate
分子名称: CYTIDINE-5'-MONOPHOSPHATE, Cytidylate kinase, PHOSPHATE ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2012-01-30
公開日2012-02-08
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015

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