5TTP
 
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5TV4
 | | 3D cryo-EM reconstruction of nucleotide-free MsbA in lipid nanodisc | | 分子名称: | 3-HYDROXY-TETRADECANOIC ACID, L-glycero-alpha-D-manno-heptopyranose-(1-7)-L-glycero-alpha-D-manno-heptopyranose-(1-3)-L-glycero-alpha-D-manno-heptopyranose-(1-5)-[3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)]3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-alpha-D-glucopyranose-(1-6)-2-amino-2-deoxy-alpha-D-glucopyranose, LAURIC ACID, ... | | 著者 | Mi, W, Walz, T, Liao, M. | | 登録日 | 2016-11-08 | | 公開日 | 2017-09-20 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural basis of MsbA-mediated lipopolysaccharide transport.
Nature, 549, 2017
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2PER
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7T6D
 | | CryoEM structure of the YejM/LapB complex | | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, 2-(HEXADECANOYLOXY)-1-[(PHOSPHONOOXY)METHYL]ETHYL HEXADECANOATE, Inner membrane protein YejM, ... | | 著者 | Mi, W, Shu, S. | | 登録日 | 2021-12-13 | | 公開日 | 2022-08-17 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Regulatory mechanisms of lipopolysaccharide synthesis in Escherichia coli.
Nat Commun, 13, 2022
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8V24
 | | LapB cytoplasmic domain in complex with LpxC | | 分子名称: | ACETATE ION, Lipopolysaccharide assembly protein B, UDP-3-O-acyl-N-acetylglucosamine deacetylase, ... | | 著者 | Mi, W, Shu, S. | | 登録日 | 2023-11-21 | | 公開日 | 2024-04-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Dual function of LapB (YciM) in regulating Escherichia coli lipopolysaccharide synthesis.
Proc.Natl.Acad.Sci.USA, 121, 2024
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5V7V
 | | Cryo-EM structure of ERAD-associated E3 ubiquitin-protein ligase component HRD3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ERAD-associated E3 ubiquitin-protein ligase component HRD3, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Mi, W, Schoebel, S, Stein, A, Rapoport, T.A, Liao, M. | | 登録日 | 2017-03-20 | | 公開日 | 2017-08-16 | | 最終更新日 | 2024-10-16 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3.
Nature, 548, 2017
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3NR2
 | | Crystal structure of Caspase-6 zymogen | | 分子名称: | Caspase-6 | | 著者 | Su, X.-D, Wang, X.-J, Liu, X, Mi, W, Wang, K.-T. | | 登録日 | 2010-06-30 | | 公開日 | 2010-10-27 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structures of human caspase 6 reveal a new mechanism for intramolecular cleavage self-activation
Embo Rep., 11, 2010
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3MXZ
 | | Crystal Structure of tubulin folding cofactor A from Arabidopsis thaliana | | 分子名称: | NITRATE ION, Tubulin-specific chaperone A | | 著者 | Lu, L, Nan, J, Mi, W, Su, X.D, Li, Y. | | 登録日 | 2010-05-08 | | 公開日 | 2010-09-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.599 Å) | | 主引用文献 | Crystal structure of tubulin folding cofactor A from Arabidopsis thaliana and its beta-tubulin binding characterization
Febs Lett., 584, 2010
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8DFM
 | | Ectodomain of full-length wild-type KIT-SCF dimers | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Mast/stem cell growth factor receptor Kit, ... | | 著者 | Krimmer, S.G, Bertoletti, N, Mi, W, Schlessinger, J. | | 登録日 | 2022-06-22 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | | 主引用文献 | Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8DFQ
 | | Ectodomain of full-length KIT(T417I,delta418-419)-SCF dimers | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Mast/stem cell growth factor receptor Kit, ... | | 著者 | Krimmer, S.G, Bertoletti, N, Mi, W, Schlessinger, J. | | 登録日 | 2022-06-22 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.96 Å) | | 主引用文献 | Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention.
Proc.Natl.Acad.Sci.USA, 120, 2023
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8DFP
 | | Ectodomain of full-length KIT(DupA502,Y503)-SCF dimers | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform 2 of Mast/stem cell growth factor receptor Kit, ... | | 著者 | Bertoletti, N, Krimmer, S.G, Mi, W, Schlessinger, J. | | 登録日 | 2022-06-22 | | 公開日 | 2023-03-29 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.17 Å) | | 主引用文献 | Cryo-EM analyses of KIT and oncogenic mutants reveal structural oncogenic plasticity and a target for therapeutic intervention.
Proc.Natl.Acad.Sci.USA, 120, 2023
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5V6P
 | | CryoEM structure of the ERAD-associated E3 ubiquitin-protein ligase HRD1 | | 分子名称: | ERAD-associated E3 ubiquitin-protein ligase HRD1 | | 著者 | Schoebel, S, Mi, W, Stein, A, Rapoport, T.A, Liao, M. | | 登録日 | 2017-03-17 | | 公開日 | 2017-08-16 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3.
Nature, 548, 2017
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6DBR
 | | Cryo-EM structure of RAG in complex with one melted RSS and one unmelted RSS | | 分子名称: | CALCIUM ION, Forward strand of melted RSS substrate DNA, Forward strand of unmelted RSS substrate DNA, ... | | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | | 登録日 | 2018-05-03 | | 公開日 | 2018-08-01 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
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6DBL
 | | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs | | 分子名称: | CALCIUM ION, Molecule name: Forward strand of 12-RSS substrate DNA, Molecule name: Forward strand of 23-RSS substrate DNA, ... | | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | | 登録日 | 2018-05-03 | | 公開日 | 2018-08-01 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (5 Å) | | 主引用文献 | DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
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6DBQ
 | | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs | | 分子名称: | CALCIUM ION, Molecule name: Forward strand of 12-RSS substrate DNA, Molecule name: Forward strand of 23-RSS substrate DNA, ... | | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | | 登録日 | 2018-05-03 | | 公開日 | 2018-08-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.22 Å) | | 主引用文献 | DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
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6DBW
 | | Cryo-EM structure of RAG in complex with 12-RSS substrate DNA | | 分子名称: | CALCIUM ION, Forward strand of 12-RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ... | | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | | 登録日 | 2018-05-03 | | 公開日 | 2018-08-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | | 主引用文献 | DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
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6DBT
 | | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs | | 分子名称: | CALCIUM ION, Forward strand of 12-RSS substrate DNA, Forward strand of 23-RSS substrate DNA, ... | | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | | 登録日 | 2018-05-03 | | 公開日 | 2018-08-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.3 Å) | | 主引用文献 | DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
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6DBU
 | | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs | | 分子名称: | CALCIUM ION, Forward strand RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ... | | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | | 登録日 | 2018-05-03 | | 公開日 | 2018-08-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
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6DBI
 | | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS nicked DNA intermediates | | 分子名称: | CALCIUM ION, Forward strand of 12-RSS signal end, Forward strand of 23-RSS signal end, ... | | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | | 登録日 | 2018-05-03 | | 公開日 | 2018-08-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
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6DBX
 | | Cryo-EM structure of RAG in complex with 12-RSS substrate DNA | | 分子名称: | CALCIUM ION, Forward strand of 12-RSS substrate DNA, Recombination activating gene 1 - MBP chimera, ... | | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | | 登録日 | 2018-05-03 | | 公開日 | 2018-08-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
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6DBV
 | | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs | | 分子名称: | CALCIUM ION, Forward strand of 12-RSS substrate DNA, Forward strand of 23-RSS substrate DNA, ... | | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | | 登録日 | 2018-05-03 | | 公開日 | 2018-08-01 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (4.29 Å) | | 主引用文献 | DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
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6DBO
 | | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS substrate DNAs | | 分子名称: | CALCIUM ION, Forward strand of substrate RSS DNA, Recombination activating gene 1 - MBP chimera, ... | | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | | 登録日 | 2018-05-03 | | 公開日 | 2018-08-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
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6DBJ
 | | Cryo-EM structure of RAG in complex with 12-RSS and 23-RSS nicked DNA intermediates | | 分子名称: | CALCIUM ION, Forward stand of RSS signal end, Forward strand of coding flank, ... | | 著者 | Wu, H, Liao, M, Ru, H, Mi, W. | | 登録日 | 2018-05-03 | | 公開日 | 2018-08-01 | | 最終更新日 | 2024-03-13 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | DNA melting initiates the RAG catalytic pathway.
Nat. Struct. Mol. Biol., 25, 2018
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6E83
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5XNV
 | | Crystal structure of YEATS2 YEATS bound to H3K27ac peptide | | 分子名称: | ALA-ALA-ARG-ALY-SER-ALA-PRO-ALA, AMMONIUM ION, CHLORIDE ION, ... | | 著者 | Li, H.T, Guan, H.P, Zhao, D. | | 登録日 | 2017-05-24 | | 公開日 | 2017-11-01 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.696 Å) | | 主引用文献 | YEATS2 links histone acetylation to tumorigenesis of non-small cell lung cancer.
Nat Commun, 8, 2017
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