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Coproporphyrinogen III oxidase from Leishmania naiffi
分子名称:	ACETATE ION, COPROPORPHYRINOGEN III OXIDASE, GLYCEROL
著者	Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日	2008-08-19
公開日	2008-09-02
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (2.27 Å)
主引用文献	Structural investigation of a protozoan coproporphyrinogen III oxidase To be Published

4Y5Q

Activated Calcium-Dependent Protein Kinase 1 from Cryptosporidium parvum (CpCDPK1) in complex with AMP
分子名称:	ADENOSINE MONOPHOSPHATE, CALCIUM ION, Calmodulin-domain protein kinase 1, ...
著者	Merritt, E.A, Larson, E.T, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日	2015-02-11
公開日	2015-02-25
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Activated Calcium-Dependent Protein Kinase 1 from Cryptosporidium parvum (CpCDPK1) in complex with AMP To Be Published

3IAL

Giardia lamblia Prolyl-tRNA synthetase in complex with prolyl-adenylate
分子名称:	5'-O-[(R)-hydroxy{[(2S)-pyrrolidin-2-ylcarbonyl]oxy}phosphoryl]adenosine, GLYCEROL, Prolyl-tRNA synthetase
著者	Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日	2009-07-14
公開日	2009-08-11
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Structure of the prolyl-tRNA synthetase from the eukaryotic pathogen Giardia lamblia. Acta Crystallogr.,Sect.D, 68, 2012

3I7F

Aspartyl tRNA synthetase from Entamoeba histolytica
分子名称:	Aspartyl-tRNA synthetase
著者	Arakaki, T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日	2009-07-08
公開日	2009-07-21
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Crystal structure of the aspartyl-tRNA synthetase from Entamoeba histolytica. Mol.Biochem.Parasitol., 169, 2010

3I79

Calcium-Dependent Protein Kinase 1 from Toxoplasma gondii (TgCDPK1)
分子名称:	1,2-ETHANEDIOL, Calmodulin-domain protein kinase 1
著者	Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日	2009-07-08
公開日	2009-08-11
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (2.04 Å)
主引用文献	Toxoplasma gondii calcium-dependent protein kinase 1 is a target for selective kinase inhibitors. Nat.Struct.Mol.Biol., 17, 2010

1YJ8

Initial structural analysis of Plasmodium falciparum Glycerol-3-phosphate dehydrogenase
分子名称:	glycerol-3-phosphate dehydrogenase
著者	Robien, M.A, Hol, W.G.J, Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日	2005-01-13
公開日	2005-02-01
最終更新日	2024-02-14
実験手法	X-RAY DIFFRACTION (2.85 Å)
主引用文献	Initial structural analysis of Plasmodium falciparum Glycerol-3-phosphate dehydrogenase To be Published

3KKK

Y92C catalytic residue mutant of Phosphoglycerate Mutase from Plasmodium falciparum
分子名称:	Phosphoglycerate mutase
著者	Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日	2009-11-05
公開日	2009-11-17
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (2.08 Å)
主引用文献	Structure of a phosphoglycerate mutase from Plasmodium falciparum To be Published

3MWU

Activated Calcium-Dependent Protein Kinase 1 from Cryptosporidium parvum (CpCDPK1) in complex with bumped kinase inhibitor RM-1-95
分子名称:	3-(naphthalen-1-ylmethyl)-1-(piperidin-4-ylmethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, CALCIUM ION, Calmodulin-domain protein kinase 1
著者	Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日	2010-05-06
公開日	2010-07-21
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (1.98 Å)
主引用文献	Discovery of Potent and Selective Inhibitors of Calcium-Dependent Protein Kinase 1 (CDPK1) from C. parvum and T. gondii. ACS Med Chem Lett, 1, 2010

3S4O

Protein Tyrosine Phosphatase (putative) from Leishmania major
分子名称:	4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Protein tyrosine phosphatase-like protein, THIOSULFATE
著者	Merritt, E.A, Arakaki, T, Medical Structural Genomics of Pathogenic Protozoa (MSGPP), Structural Genomics of Pathogenic Protozoa Consortium (SGPP)
登録日	2011-05-19
公開日	2011-06-15
最終更新日	2024-10-09
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Protein Tyrosine Phosphatase from Leishmania major To be Published

3EJO

Coproporphyrinogen III oxidase from Leishmania donovani
分子名称:	ACETATE ION, Coproporphyrinogen III oxidase
著者	Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日	2008-09-18
公開日	2008-10-14
最終更新日	2023-08-30
実験手法	X-RAY DIFFRACTION (2.3 Å)
主引用文献	Structural investigation of a protozoan coproporphyrinogen iii oxidase to be published

4F4R

Crystal structure of D-mannonate dehydratase homolog from Chromohalobacter salexigens (Target EFI-502114), with bound NA, ordered loop
分子名称:	CHLORIDE ION, D-mannonate dehydratase, GLYCEROL, ...
著者	Vetting, M.W, Toro, R, Bhosle, R, Al Obaidi, N.F, Morisco, L.L, Wasserman, S.R, Sojitra, S, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Hillerich, B, Love, J, Seidel, R.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI), Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日	2012-05-11
公開日	2012-06-27
最終更新日	2023-09-13
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Crystal structure of D-mannonate dehydratase homolog from Chromohalobacter salexigens (Target EFI-502114), with bound NA, ordered loop to be published

3M4Q

Entamoeba histolytica asparaginyl-tRNA synthetase (AsnRS)
分子名称:	Asparaginyl-tRNA synthetase, putative
著者	Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日	2010-03-11
公開日	2010-03-23
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	X-ray crystal structure of asparaginyl-tRNA synthetase from the eukaryotic human pathogen Entamoeba histolytica. to be published

3LX3

Plasmodium vivax 6-pyruvoyltetrahydropterin synthase (PTPS) in complex with xanthopterin
分子名称:	2-amino-1,5-dihydropteridine-4,6-dione, 6-pyruvoyl tetrahydrobiopterin synthase, ZINC ION
著者	Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日	2010-02-24
公開日	2010-03-09
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (1.55 Å)
主引用文献	Structural analysis of the dual-functional 6-pyruvoyltetrahydropterin synthase from Malaria parasites. to be published

3M0N

Plasmodium vivax 6-pyruvoyltetrahydropterin synthase (PTPS), E37A catalytic residue mutant
分子名称:	PTERINE, Putative 6-pyruvoyl tetrahydrobiopterin synthase, ZINC ION
著者	Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日	2010-03-03
公開日	2010-04-07
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Structural analysis of the dual-functional 6-pyruvoyltetrahydropterin synthase from Malaria parasites. to be published

3M4P

Entamoeba histolytica asparaginyl-tRNA synthetase (AsnRS) in complex with asparaginyl-adenylate
分子名称:	4-AMINO-1,4-DIOXOBUTAN-2-AMINIUM ADENOSINE-5'-MONOPHOSPHATE, Asparaginyl-tRNA synthetase, putative, ...
著者	Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日	2010-03-11
公開日	2010-03-23
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (2.83 Å)
主引用文献	X-ray crystal structure of asparaginyl-tRNA synthetase from the eukaryotic human pathogen Entamoeba histolytica. to be published

3LZE

Plasmodium vivax 6-pyruvoyltetrahydropterin synthase (PTPS), E37C catalytic residue mutant
分子名称:	PTERINE, Putative 6-pyruvoyl tetrahydrobiopterin synthase, ZINC ION
著者	Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日	2010-03-01
公開日	2010-04-07
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Structural analysis of the dual-functional 6-pyruvoyltetrahydropterin synthase from Malaria parasites. to be published

3LSQ

Trypanosoma brucei seryl-tRNA synthetase
分子名称:	MALONATE ION, SODIUM ION, Seryl-tRNA synthetase
著者	Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日	2010-02-12
公開日	2010-03-02
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (2.1 Å)
主引用文献	X-ray crystal structure of Seryl-tRNA synthetase from the eukaryotic parasite Trypanosoma brucei. to be published

3LSS

Trypanosoma brucei seryl-tRNA synthetase in complex with ATP
分子名称:	ADENOSINE-5'-TRIPHOSPHATE, MALONATE ION, SODIUM ION, ...
著者	Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日	2010-02-12
公開日	2010-03-02
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (1.95 Å)
主引用文献	X-ray crystal structure of Seryl-tRNA synthetase from the eukaryotic parasite Trypanosoma brucei. to be published

3KFL

Leishmania major methionyl-tRNA synthetase in complex with methionyladenylate and pyrophosphate
分子名称:	1,2-ETHANEDIOL, FORMIC ACID, MAGNESIUM ION, ...
著者	Larson, E.T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日	2009-10-27
公開日	2010-10-27
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Structure of Leishmania major methionyl-tRNA synthetase in complex with intermediate products methionyladenylate and pyrophosphate. Biochimie, 93, 2011

3LC0

Histidyl-tRNA synthetase from Trypanosoma cruzi (Histidine complex)
分子名称:	HISTIDINE, Histidyl-tRNA synthetase
著者	Merritt, E.A, Larson, E.T, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日	2010-01-08
公開日	2010-01-19
最終更新日	2024-02-21
実験手法	X-RAY DIFFRACTION (1.8 Å)
主引用文献	Crystal Structures of Trypanosomal Histidyl-tRNA Synthetase Illuminate Differences between Eukaryotic and Prokaryotic Homologs. J.Mol.Biol., 397, 2010

3SO4

Methionine-adenosyltransferase from Entamoeba histolytica
分子名称:	ACETATE ION, Methionine-adenosyltransferase
著者	Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日	2011-06-29
公開日	2011-07-20
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (3.18 Å)
主引用文献	Methionine-adenosyltransferase from Entamoeba histolytica To be Published

3HZR

Tryptophanyl-tRNA synthetase homolog from Entamoeba histolytica
分子名称:	Tryptophanyl-tRNA synthetase
著者	Arakaki, T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日	2009-06-24
公開日	2009-07-28
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (3 Å)
主引用文献	Crystal structures of three protozoan homologs of tryptophanyl-tRNA synthetase. Mol.Biochem.Parasitol., 177, 2011

3I05

Tryptophanyl-tRNA synthetase from Trypanosoma brucei
分子名称:	Tryptophanyl-tRNA synthetase
著者	Arakaki, T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日	2009-06-24
公開日	2009-07-28
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	Crystal structures of three protozoan homologs of tryptophanyl-tRNA synthetase. Mol.Biochem.Parasitol., 177, 2011

3HV0

Tryptophanyl-tRNA synthetase from Cryptosporidium parvum
分子名称:	TRYPTOPHAN, Tryptophanyl-tRNA synthetase
著者	Arakaki, T, Merritt, E.A, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日	2009-06-15
公開日	2009-06-30
最終更新日	2023-09-06
実験手法	X-RAY DIFFRACTION (2.42 Å)
主引用文献	Crystal structures of three protozoan homologs of tryptophanyl-tRNA synthetase. Mol.Biochem.Parasitol., 177, 2011

3P0I

Leishmania major Tyrosyl-tRNA synthetase in complex with tyrosinol, cubic crystal form
分子名称:	4-[(2S)-2-amino-3-hydroxypropyl]phenol, Tyrosyl-tRNA synthetase
著者	Merritt, E.A, Larson, E.T, Medical Structural Genomics of Pathogenic Protozoa (MSGPP)
登録日	2010-09-28
公開日	2011-03-23
最終更新日	2023-12-06
実験手法	X-RAY DIFFRACTION (3.13 Å)
主引用文献	The Double-Length Tyrosyl-tRNA Synthetase from the Eukaryote Leishmania major Forms an Intrinsically Asymmetric Pseudo-Dimer. J.Mol.Biol., 409, 2011

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表示件数:	25
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