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3LX3

Plasmodium vivax 6-pyruvoyltetrahydropterin synthase (PTPS) in complex with xanthopterin

Summary for 3LX3
Entry DOI10.2210/pdb3lx3/pdb
Related1Y13 2A0S 3lze 3m0n
Descriptor6-pyruvoyl tetrahydrobiopterin synthase, ZINC ION, 2-amino-1,5-dihydropteridine-4,6-dione, ... (4 entities in total)
Functional Keywordspts, ptp synthase, ptps, metal-binding, tetrahydrobiopterin biosynthesis, folate biosynthesis, structural genomics, medical structural genomics of pathogenic protozoa, msgpp, biosynthetic protein
Biological sourcePlasmodium vivax
Total number of polymer chains1
Total formula weight21237.44
Authors
Larson, E.T.,Merritt, E.A.,Medical Structural Genomics of Pathogenic Protozoa (MSGPP) (deposition date: 2010-02-24, release date: 2010-03-09, Last modification date: 2023-09-06)
Primary citationLarson, E.T.,Bosch, J.,Kim, J.E.,Mueller, N.,Verlinde, C.L.M.J.,Van Voorhis, W.C.,Buckner, F.S.,Fan, E.,Hol, W.G.J.,Merritt, E.A.
Structural analysis of the dual-functional 6-pyruvoyltetrahydropterin synthase from Malaria parasites.
to be published,
Experimental method
X-RAY DIFFRACTION (1.55 Å)
Structure validation

227561

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