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5JN7
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BU of 5jn7 by Molmil
Carbonic Anhydrase II In Complex WITH U-CH3
分子名称: 4-{[(3,5-dimethylphenyl)carbamoyl]amino}benzene-1-sulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ...
著者McKenna, R, Mboge, M.Y, Mahon, B.P.
登録日2016-04-29
公開日2017-05-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.517 Å)
主引用文献Carbonic Anhydrase II In Complex WITH U-CH3
To Be Published
5JN3
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BU of 5jn3 by Molmil
Carbonic Anhydrase IX-mimic IN Complex WITH U-F
分子名称: 4-{[(4-fluorophenyl)carbamoyl]amino}benzenesulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ...
著者McKenna, R, Mboge, M.Y, Mahon, B.P.
登録日2016-04-29
公開日2017-05-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Carbonic Anhydrase IX-mimic IN Complex WITH U-F
To Be Published
5JMZ
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BU of 5jmz by Molmil
Carbonic Anhydrase IX-mimic IN Complex WITH U-NO2
分子名称: 4-{[(3-nitrophenyl)carbamoyl]amino}benzenesulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ...
著者McKenna, R, Mboge, M.Y, Mahon, B.P.
登録日2016-04-29
公開日2017-05-03
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Carbonic Anhydrase IX-mimic IN Complex WITH U-NO2
To Be Published
2BPA
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BU of 2bpa by Molmil
ATOMIC STRUCTURE OF SINGLE-STRANDED DNA BACTERIOPHAGE PHIX174 AND ITS FUNCTIONAL IMPLICATIONS
分子名称: DNA (5'-D(*AP*AP*AP*AP*C)-3'), PROTEIN (SUBUNIT OF BACTERIOPHAGE PHIX174)
著者McKenna, R, Xia, D, Willingmann, P, Ilag, L.L, Krishnaswamy, S, Rossmann, M.G, Olson, N.H, Baker, T.S, Incardona, N.L.
登録日1991-12-03
公開日1991-12-03
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Atomic structure of single-stranded DNA bacteriophage phi X174 and its functional implications.
Nature, 355, 1992
8UGQ
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BU of 8ugq by Molmil
CryoEM Structure of Maize Streak Virus (MSV) - Geminivirus
分子名称: Capsid protein, DNA (5'-D(P*CP*GP*AP*AP*CP*CP*CP*CP*A)-3')
著者McKenna, R, Bennett, A.B, Mietzsch, M, Hull, J.A.
登録日2023-10-05
公開日2023-11-22
実験手法ELECTRON MICROSCOPY (3.17 Å)
主引用文献The two states of Maize Streak Virus (MSV) Geminivirus Architecture
To Be Published
1KVP
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BU of 1kvp by Molmil
STRUCTURAL ANALYSIS OF THE SPIROPLASMA VIRUS, SPV4, IMPLICATIONS FOR EVOLUTIONARY VARIATION TO OBTAIN HOST DIVERSITY AMONG THE MICROVIRIDAE, ELECTRON MICROSCOPY, ALPHA CARBONS ONLY
分子名称: SPV4 CAPSID PROTEIN VP1
著者McKenna, R.
登録日1997-12-12
公開日1999-02-23
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (27 Å)
主引用文献Structural analysis of the Spiroplasma virus, SpV4: implications for evolutionary variation to obtain host diversity among the Microviridae.
Structure, 6, 1998
8E8P
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BU of 8e8p by Molmil
GSTZ1A
分子名称: Maleylacetoacetate isomerase
著者McKenna, R, Combs, J.E.
登録日2022-08-25
公開日2023-10-18
実験手法X-RAY DIFFRACTION (2.281 Å)
主引用文献Structure of human GSTZ1-1 and modifications by dichloroacetate
To Be Published
9DC7
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BU of 9dc7 by Molmil
AAV5 at 80 Degree Celsius
分子名称: Capsid protein
著者McKenna, R, Bennett, A, Gliwa, K.
登録日2024-08-25
公開日2025-01-15
最終更新日2025-04-16
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Biophysical and structural insights into AAV genome ejection.
J.Virol., 99, 2025
7RRE
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BU of 7rre by Molmil
Carbonic Anhydrase II in complex with Beta-Galactose-2C
分子名称: 2-[1-(1,1,3-trioxo-2,3-dihydro-1H-1lambda~6~,2-benzothiazol-6-yl)-1H-1,2,3-triazol-4-yl]ethyl beta-L-gulopyranoside, Carbonic anhydrase 2, GLYCEROL, ...
著者McKenna, R, Combs, J.E.
登録日2021-08-09
公開日2022-08-24
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.44 Å)
主引用文献Inhibition of Carbonic Anhydrase IX and Monocarboxylate Transporters 1 and 4 in breast cancer via novel inhibition with Beta-Galactose 2C
To Be Published
7SUW
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BU of 7suw by Molmil
Carbonic Anhydrase IX-mimic with 2-((3-Aminopropyl)(phenethyl)amino)-N-(furan-2-ylmethyl)-N-(4-sulfamoylphenethyl)acetamide
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Carbonic anhydrase 2, N-(2-{[(furan-2-yl)methyl][2-(4-sulfamoylphenyl)ethyl]amino}-2-oxoethyl)-N-(2-phenylethyl)-beta-alanine, ...
著者McKenna, R, Combs, J.E.
登録日2021-11-18
公開日2022-04-06
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.456 Å)
主引用文献The three-tails approach as a new strategy to improve selectivity of action of sulphonamide inhibitors against tumour-associated carbonic anhydrase IX and XII.
J Enzyme Inhib Med Chem, 37, 2022
6UZU
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BU of 6uzu by Molmil
Carbonic Anhydrase IX-mimic In Complex WITH U-CH3
分子名称: 4-{[(3,5-dimethylphenyl)carbamoyl]amino}benzene-1-sulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ...
著者McKenna, R, Mboge, M.Y, Mahon, B.P.
登録日2019-11-15
公開日2020-10-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure activity study of carbonic anhydrase IX: Selective inhibition with ureido-substituted benzenesulfonamides.
Eur J Med Chem, 132, 2017
1LCU
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BU of 1lcu by Molmil
Polylysine Induces an Antiparallel Actin Dimer that Nucleates Filament Assembly: Crystal Structure at 3.5 A Resolution
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
著者Bubb, M.R, Govindasamy, L, Yarmola, E.G, Vorobiev, S.M, Almo, S.C, Somasundaram, T, Chapman, M.S, Agbandje-Mckenna, M, Mckenna, R.
登録日2002-04-06
公開日2002-05-01
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Polylysine induces an antiparallel actin dimer that nucleates filament assembly: crystal structure at 3.5-A resolution.
J.Biol.Chem., 277, 2002
6E9D
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BU of 6e9d by Molmil
Sub-2 Angstrom Ewald Curvature-Corrected Single-Particle Cryo-EM Reconstruction of AAV-2 L336C
分子名称: Capsid protein VP1
著者Tan, Y.Z, Aiyer, S, Mietzsch, M, Hull, J.A, McKenna, R, Baker, T.S, Agbandje-McKenna, M, Lyumkis, D.
登録日2018-07-31
公開日2018-08-15
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (1.86 Å)
主引用文献Sub-2 angstrom Ewald curvature corrected structure of an AAV2 capsid variant.
Nat Commun, 9, 2018
3D9Z
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BU of 3d9z by Molmil
Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties
分子名称: 5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide, Carbonic anhydrase 2, ZINC ION
著者Genis, C, Sippel, K.H, Case, N, Govindasamy, L, Agbandje-Mckenna, M, Mckenna, R.
登録日2008-05-28
公開日2009-03-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties
Biochemistry, 48, 2009
3DCS
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BU of 3dcs by Molmil
Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties
分子名称: Carbonic anhydrase 2, N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene)acetamide, ZINC ION
著者Genis, C, Sippel, K.H, Case, N, Govindasamy, L, Agbandje-Mckenna, M, Mckenna, R.
登録日2008-06-04
公開日2009-03-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties
Biochemistry, 48, 2009
3DCW
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BU of 3dcw by Molmil
Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties
分子名称: 6-ethoxy-1,3-benzothiazole-2-sulfonamide, Carbonic anhydrase 2, ZINC ION
著者Genis, C, Sippel, K.H, Case, N, Govindasamy, L, Agbandje-Mckenna, M, Mckenna, R.
登録日2008-06-04
公開日2009-03-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties
Biochemistry, 48, 2009
5IPK
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BU of 5ipk by Molmil
Structure of the R432A variant of Adeno-associated virus type 2 VLP
分子名称: Capsid protein VP1
著者Drouin, L.M, Lins, B, Janssen, M.E, Bennet, A, Chipman, P, McKenna, R, Chen, W, Muzyczka, N, Cardone, G, Baker, T.S, Agbandje-McKenna, M.
登録日2016-03-09
公開日2016-07-20
最終更新日2025-06-04
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Cryo-electron Microscopy Reconstruction and Stability Studies of the Wild Type and the R432A Variant of Adeno-associated Virus Type 2 Reveal that Capsid Structural Stability Is a Major Factor in Genome Packaging.
J.Virol., 90, 2016
5IPI
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BU of 5ipi by Molmil
Structure of Adeno-associated virus type 2 VLP
分子名称: Capsid protein VP1
著者Drouin, L.M, Lins, B, Janssen, M.E, Bennet, A, Chipman, P, McKenna, R, Chen, W, Muzyczka, N, Cardone, G, Baker, T.S, Agbandje-McKenna, M.
登録日2016-03-09
公開日2016-07-20
最終更新日2025-05-28
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Cryo-electron Microscopy Reconstruction and Stability Studies of the Wild Type and the R432A Variant of Adeno-associated Virus Type 2 Reveal that Capsid Structural Stability Is a Major Factor in Genome Packaging.
J.Virol., 90, 2016
5JJ8
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BU of 5jj8 by Molmil
Crystal Structure of the Beta Carbonic Anhydrase psCA3 isolated from Pseudomonas aeruginosa - alternate crystal packing form
分子名称: Carbonic anhydrase, ZINC ION
著者Pinard, M.A, Kurian, J.J, Aggarwal, M, Agbandje-McKenna, M, McKenna, R.
登録日2016-04-22
公開日2016-07-06
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.585 Å)
主引用文献Cryoannealing-induced space-group transition of crystals of the carbonic anhydrase psCA3.
Acta Crystallogr.,Sect.F, 72, 2016
7RL1
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BU of 7rl1 by Molmil
AAVrh.10-7x capsid
分子名称: Capsid protein VP1, DNA (5'-D(*CP*A)-3')
著者Mietzsch, M, McKenna, R.
登録日2021-07-23
公開日2021-09-08
最終更新日2025-06-04
実験手法ELECTRON MICROSCOPY (2.71 Å)
主引用文献Structural Study of Aavrh.10 Receptor and Antibody Interactions.
J.Virol., 95, 2021
7S1W
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BU of 7s1w by Molmil
The AAVrh.10-glycan complex
分子名称: Capsid protein VP1, beta-D-galactopyranose
著者Mietzsch, M, McKenna, R.
登録日2021-09-02
公開日2021-09-22
最終更新日2025-05-14
実験手法ELECTRON MICROSCOPY (3.09 Å)
主引用文献Structural Study of Aavrh.10 Receptor and Antibody Interactions.
J.Virol., 95, 2021
3D92
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BU of 3d92 by Molmil
Human carbonic anhydrase II bound with substrate carbon dioxide
分子名称: CARBON DIOXIDE, GLYCEROL, ZINC ION, ...
著者Domsic, J.F, Avvaru, B.S, McKenna, R.
登録日2008-05-26
公開日2008-09-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Entrapment of carbon dioxide in the active site of carbonic anhydrase II
J.Biol.Chem., 283, 2008
4XZ5
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BU of 4xz5 by Molmil
Structure of the thermostable alpha-Carbonic Anydrase from Thiomicrospira crunogena XCL-2 gammaproteobacterium
分子名称: BICARBONATE ION, Carbonic anhydrase, alpha family, ...
著者Mahon, B.P, Diaz-Torres, N.A, Pinard, M.A, McKenna, R.
登録日2015-02-03
公開日2015-07-29
最終更新日2024-11-13
実験手法X-RAY DIFFRACTION (2.596 Å)
主引用文献Structural and biophysical characterization of the alpha-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2: insights into engineering thermostable enzymes for CO2 sequestration.
Acta Crystallogr.,Sect.D, 71, 2015
1MOO
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BU of 1moo by Molmil
Site Specific Mutant (H64A) of Human Carbonic Anhydrase II at high resolution
分子名称: 4-METHYLIMIDAZOLE, Carbonic Anhydrase II, MERCURY (II) ION, ...
著者Duda, D.M, Govindasamy, L, Agbandje-McKenna, M, Tu, C.K, Silverman, D.N, McKenna, R.
登録日2002-09-09
公開日2002-09-18
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献The refined atomic structure of carbonic anhydrase II at 1.05 A resolution: implications of chemical rescue of proton transfer.
Acta Crystallogr.,Sect.D, 59, 2003
2NWO
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BU of 2nwo by Molmil
Structural and kinetic effect of hydrophobic mutations in the active site of human carbonic anhydrase II
分子名称: Carbonic anhydrase 2, ZINC ION
著者Fisher, S.Z, McKenna, R.
登録日2006-11-16
公開日2007-04-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Speeding Up Proton Transfer in a Fast Enzyme: Kinetic and Crystallographic Studies on the Effect of Hydrophobic Amino Acid Substitutions in the Active Site of Human Carbonic Anhydrase II.
Biochemistry, 46, 2007

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