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6XAR
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BU of 6xar by Molmil
Structure of CBL tyrosine kinase binding domain (TKBD) with C-terminal tail of Src-like kinase protein 2 (SLAP2)
分子名称: CALCIUM ION, E3 ubiquitin-protein ligase CBL, Src-like-adapter 2
著者Wybenga-Groot, L.E, McGlade, C.J.
登録日2020-06-04
公開日2021-03-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.501 Å)
主引用文献SLAP2 Adaptor Binding Disrupts c-CBL Autoinhibition to Activate Ubiquitin Ligase Function.
J.Mol.Biol., 433, 2021
1H3H
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BU of 1h3h by Molmil
Structural Basis for Specific Recognition of an RxxK-containing SLP-76 peptide by the Gads C-terminal SH3 domain
分子名称: GRB2-RELATED ADAPTOR PROTEIN 2, LYMPHOCYTE CYTOSOLIC PROTEIN 2
著者Liu, Q, Berry, D, Nash, P, Pawson, T, McGlade, C.J, Li, S.S.
登録日2002-09-03
公開日2003-03-06
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structural Basis for Specific Binding of the Gads SH3 Domain to an Rxxk Motif-Containing Slp-76 Peptide: A Novel Mode of Peptide Recognition
Mol.Cell, 11, 2003
2NMB
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BU of 2nmb by Molmil
DNUMB PTB DOMAIN COMPLEXED WITH A PHOSPHOTYROSINE PEPTIDE, NMR, ENSEMBLE OF STRUCTURES.
分子名称: PROTEIN (GPPY PEPTIDE), PROTEIN (NUMB PROTEIN)
著者Li, S.-C, Zwahlen, C, Vincent, S.J.F, McGlade, C.J, Pawson, T, Forman-Kay, J.D.
登録日1998-10-29
公開日1998-11-04
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structure of a Numb PTB domain-peptide complex suggests a basis for diverse binding specificity.
Nat.Struct.Biol., 5, 1998
4M4Z
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BU of 4m4z by Molmil
SH3 and SH2 domains of human Src-like adaptor protein 2 (SLAP2)
分子名称: Src-like-adapter 2
著者Wybenga-Groot, L.E, McGlade, C.J.
登録日2013-08-07
公開日2013-11-06
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of Src-like adaptor protein 2 reveals close association of SH3 and SH2 domains through beta-sheet formation.
Cell Signal, 25, 2013
4TZI
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BU of 4tzi by Molmil
Structure of unliganded Lyn SH2 domain
分子名称: Tyrosine-protein kinase Lyn
著者Wybenga-Groot, L.E.
登録日2014-07-10
公開日2015-01-21
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Tyrosine Phosphorylation of the Lyn Src Homology 2 (SH2) Domain Modulates Its Binding Affinity and Specificity.
Mol.Cell Proteomics, 14, 2015
4PDP
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BU of 4pdp by Molmil
Crystal structure of Rad53 kinase domain and SCD2
分子名称: Serine/threonine-protein kinase RAD53
著者Wybenga-Groot, L.E, Ho, C.S, Ceccarelli, D.F, Sicheri, F.
登録日2014-04-19
公開日2014-05-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.591 Å)
主引用文献Structural basis of Rad53 kinase activation by dimerization and activation segment exchange.
Cell Signal., 26, 2014
4PDS
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BU of 4pds by Molmil
Crystal structure of Rad53 kinase domain and SCD2 in complex with AMPPNP
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Serine/threonine-protein kinase RAD53
著者Ho, C.S, Wybenga-Groot, L.E, Ceccarelli, D.F, Sicheri, F.
登録日2014-04-21
公開日2014-05-28
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural basis of Rad53 kinase activation by dimerization and activation segment exchange.
Cell Signal., 26, 2014
1DDM
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BU of 1ddm by Molmil
SOLUTION STRUCTURE OF THE NUMB PTB DOMAIN COMPLEXED TO A NAK PEPTIDE
分子名称: NUMB ASSOCIATE KINASE, NUMB PROTEIN
著者Zwahlen, C, Li, S.C, Kay, L.E, Pawson, T, Forman-Kay, J.D.
登録日1999-11-11
公開日2000-04-10
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Multiple modes of peptide recognition by the PTB domain of the cell fate determinant Numb.
EMBO J., 19, 2000

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