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BU of 8f48 by Molmil

Human CASQ1 mutant - S248E
分子名称:	Calsequestrin-1
著者	Mayfield, J.E, Dixon, J.E.
登録日	2022-11-10
公開日	2023-12-13
実験手法	X-RAY DIFFRACTION (2.9 Å)
主引用文献	Human CASQ1 mutant - S248E To Be Published

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BU of 4ygx by Molmil

Crystal Structure of D. melanogaster Ssu72+Symplekin bound to cis peptidomimetic CTD phospho-Ser5 peptide
分子名称:	LD40846p, Symplekin, cis peptidomimetic CTD phospho-Ser5 peptide
著者	Mayfield, J.E, Zhang, Y.
登録日	2015-02-26
公開日	2015-09-16
最終更新日	2024-11-06
実験手法	X-RAY DIFFRACTION (2.95 Å)
主引用文献	Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II. Acs Chem.Biol., 10, 2015

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BU of 4yh1 by Molmil

Structure of Human Scp1 bound to cis-proline peptidomimetic CTD phospho-Ser5 peptide
分子名称:	A small phosphatase 1, Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION
著者	Mayfield, J.E, Zhang, Y.
登録日	2015-02-26
公開日	2015-09-16
最終更新日	2024-10-30
実験手法	X-RAY DIFFRACTION (2.2 Å)
主引用文献	Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II. Acs Chem.Biol., 10, 2015

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BU of 4ygy by Molmil

Crystal Structure of Human Scp1 bound to trans-proline peptidomimetic CTD phospho-Ser5 peptide
分子名称:	Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION, peptidomimetic CTD phospho-Ser5 peptide
著者	Mayfield, J.E, Zhang, Y.
登録日	2015-02-26
公開日	2015-09-16
最終更新日	2015-10-28
実験手法	X-RAY DIFFRACTION (2.36 Å)
主引用文献	Chemical Tools To Decipher Regulation of Phosphatases by Proline Isomerization on Eukaryotic RNA Polymerase II. Acs Chem.Biol., 10, 2015

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BU of 6du3 by Molmil

Structure of Scp1 D96N bound to REST-pS861/4 peptide
分子名称:	Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION, REST-pS861
著者	Burkholder, N.T, Mayfield, J.E, Yu, X, Irani, S, Arce, D.K, Jiang, F, Matthews, W, Xue, Y, Zhang, Y.J.
登録日	2018-06-19
公開日	2018-09-26
最終更新日	2020-01-01
実験手法	X-RAY DIFFRACTION (2.58 Å)
主引用文献	Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST). J. Biol. Chem., 293, 2018

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BU of 6du2 by Molmil

Structure of Scp1 D96N bound to REST-pS861/4 peptide
分子名称:	MAGNESIUM ION, REST-pS861/4, carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform X2
著者	Burkholder, N.T, Mayfield, J.E, Yu, X, Irani, S, Arce, D.K, Jiang, F, Matthews, W, Xue, Y, Zhang, Y.J.
登録日	2018-06-19
公開日	2018-09-26
最終更新日	2024-10-16
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST). J. Biol. Chem., 293, 2018

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BU of 6k0j by Molmil

The co-crystal structure of DYRK2 with a small molecule inhibitor
分子名称:	3-(2,7-dimethoxyacridin-9-yl)sulfanylpropan-1-amine, Dual specificity tyrosine-phosphorylation-regulated kinase 2
著者	Tiantian, W, Xiao, J.
登録日	2019-05-06
公開日	2019-11-20
最終更新日	2019-12-18
実験手法	X-RAY DIFFRACTION (2.352 Å)
主引用文献	Inhibition of dual-specificity tyrosine phosphorylation-regulated kinase 2 perturbs 26S proteasome-addicted neoplastic progression. Proc.Natl.Acad.Sci.USA, 116, 2019

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BU of 5ztn by Molmil

The crystal structure of human DYRK2 in complex with Curcumin
分子名称:	(1Z,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one, Dual specificity tyrosine-phosphorylation-regulated kinase 2
著者	Ji, C.G, Xiao, J.Y.
登録日	2018-05-04
公開日	2018-07-18
最終更新日	2024-10-16
実験手法	X-RAY DIFFRACTION (2.496 Å)
主引用文献	Ancient drug curcumin impedes 26S proteasome activity by direct inhibition of dual-specificity tyrosine-regulated kinase 2. Proc. Natl. Acad. Sci. U.S.A., 115, 2018

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件を2024-11-06に公開中

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