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8WOP
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BU of 8wop by Molmil
Crystal structure of Arabidopsis thaliana UDP-glucose 4-epimerase 2 (AtUGE2) complexed with UDP, wild-type
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-glucose 4-epimerase 2, URIDINE-5'-DIPHOSPHATE
著者Matsumoto, M, Umezawa, A, Kotake, T, Fushinobu, S.
登録日2023-10-07
公開日2024-05-08
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Cytosolic UDP-L-arabinose synthesis by bifunctional UDP-glucose 4-epimerases in Arabidopsis.
Plant J., 119, 2024
8WOV
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Crystal structure of Arabidopsis thaliana UDP-glucose 4-epimerase 2 (AtUGE2) complexed with UDP, G233A mutant
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, UDP-glucose 4-epimerase 2, URIDINE-5'-DIPHOSPHATE
著者Matsumoto, M, Umezawa, A, Kotake, T, Fushinobu, S.
登録日2023-10-07
公開日2024-05-15
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Cytosolic UDP-L-arabinose synthesis by bifunctional UDP-glucose 4-epimerases in Arabidopsis.
Plant J., 119, 2024
8WOW
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BU of 8wow by Molmil
Crystal structure of Arabidopsis thaliana UDP-glucose 4-epimerase 2 (AtUGE2) complexed with UDP, I160L/G233A mutant
分子名称: NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, UDP-glucose 4-epimerase 2, ...
著者Matsumoto, M, Umezawa, A, Kotake, T, Fushinobu, S.
登録日2023-10-08
公開日2024-05-15
最終更新日2024-07-10
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Cytosolic UDP-L-arabinose synthesis by bifunctional UDP-glucose 4-epimerases in Arabidopsis.
Plant J., 119, 2024
2M1W
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BU of 2m1w by Molmil
TICAM-2 TIR domain
分子名称: TIR domain-containing adapter molecule 2
著者Enokizono, Y, Kumeta, H, Funami, K, Horiuchi, M, Sarmiento, J, Yamashita, K, Standley, D.M, Matsumoto, M, Seya, T, Inagaki, F.
登録日2012-12-07
公開日2014-01-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structures and interface mapping of the TIR domain-containing adaptor molecules involved in interferon signaling.
Proc.Natl.Acad.Sci.USA, 110, 2013
2M1X
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BU of 2m1x by Molmil
TICAM-1 TIR domain structure
分子名称: TIR domain-containing adapter molecule 1
著者Enokizono, Y, Kumeta, H, Funami, K, Horiuchi, M, Sarmiento, J, Yamashita, K, Standley, D.M, Matsumoto, M, Seya, T, Inagaki, F.
登録日2012-12-07
公開日2014-01-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structures and interface mapping of the TIR domain-containing adaptor molecules involved in interferon signaling.
Proc.Natl.Acad.Sci.USA, 110, 2013
2M63
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BU of 2m63 by Molmil
The protease-resistant N-terminal domain of TIR-domain containing adaptor molecule-1, TICAM-1
分子名称: TIR domain-containing adapter molecule 1
著者Kumeta, H, Enokizono, Y, Sakakibara, H, Ogura, K, Matsumoto, M, Seya, T, Inagaki, F.
登録日2013-03-20
公開日2014-03-05
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The N-terminal domain of TIR domain-containing adaptor molecule-1, TICAM-1.
J.Biomol.Nmr, 58, 2014
2ZYO
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BU of 2zyo by Molmil
Crystal structure of cyclo/maltodextrin-binding protein complexed with maltotetraose
分子名称: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, solute-binding protein
著者Matsumoto, M, Yamada, M, Kurakata, Y, Yoshida, H, Kamitori, S, Nishikawa, A, Tonozuka, T.
登録日2009-01-27
公開日2009-03-31
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Crystal structures of open and closed forms of cyclo/maltodextrin-binding protein
Febs J., 276, 2009
2ZYM
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BU of 2zym by Molmil
Crystal structure of cyclo/maltodextrin-binding protein complexed with alpha-cyclodextrin
分子名称: Cyclohexakis-(1-4)-(alpha-D-glucopyranose), Solute-binding protein
著者Matsumoto, M, Yamada, M, Kurakata, Y, Yoshida, H, Kamitori, S, Nishikawa, A, Tonozuka, T.
登録日2009-01-27
公開日2009-03-31
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of open and closed forms of cyclo/maltodextrin-binding protein
Febs J., 276, 2009
2ZYN
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BU of 2zyn by Molmil
Crystal structure of cyclo/maltodextrin-binding protein complexed with beta-cyclodextrin
分子名称: Cycloheptakis-(1-4)-(alpha-D-glucopyranose), Solute-binding protein
著者Matsumoto, M, Yamada, M, Kurakata, Y, Yoshida, H, Kamitori, S, Nishikawa, A, Tonozuka, T.
登録日2009-01-27
公開日2009-03-31
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of open and closed forms of cyclo/maltodextrin-binding protein
Febs J., 276, 2009
2ZYK
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BU of 2zyk by Molmil
Crystal structure of cyclo/maltodextrin-binding protein complexed with gamma-cyclodextrin
分子名称: Cyclooctakis-(1-4)-(alpha-D-glucopyranose), Solute-binding protein
著者Tonozuka, T, Sogawa, A, Yamada, M, Matsumoto, N, Yoshida, H, Kamitori, S, Ichikawa, K, Mizuno, M, Nishikawa, A, Sakano, Y.
登録日2009-01-26
公開日2009-02-10
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for cyclodextrin recognition by Thermoactinomyces vulgaris cyclo/maltodextrin-binding protein
Febs J., 274, 2007
5H08
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BU of 5h08 by Molmil
Human PTPRZ D1 domain complexed with NAZ2329
分子名称: 3-{[2-Ethoxy-5-(trifluoromethyl)benzyl]sulfanyl}-N-(phenylsulfonyl)thiophene-2-carboxamide, Receptor-type tyrosine-protein phosphatase zeta
著者Sugawara, H.
登録日2016-10-04
公開日2017-07-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Targeting PTPRZ inhibits stem cell-like properties and tumorigenicity in glioblastoma cells
Sci Rep, 7, 2017
8U31
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BU of 8u31 by Molmil
Crystal structure of PD-1 in complex with a Fab
分子名称: Fab heavy chain, Fab light chain, GLYCEROL, ...
著者Sun, D, Masureel, M.
登録日2023-09-07
公開日2024-06-19
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability.
Mabs, 16, 2024
8U32
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BU of 8u32 by Molmil
Crystal structure of PD-1 in complex with a Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ...
著者Sun, D, Masureel, M.
登録日2023-09-07
公開日2024-06-19
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Structure- and machine learning-guided engineering demonstrate that a non-canonical disulfide in an anti-PD-1 rabbit antibody does not impede antibody developability.
Mabs, 16, 2024
3VGP
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BU of 3vgp by Molmil
Crystal structure of the C-terminal globular domain of oligosaccharyltransferase (AF_0329) from Archaeoglobus fulgidus
分子名称: Transmembrane oligosaccharyl transferase, putative
著者Matsumoto, S, Igura, M, Nyirenda, J, Yuzawa, S, Noda, N.N, Inagaki, F, Kohda, D.
登録日2011-08-18
公開日2012-07-04
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal Structure of the C-Terminal Globular Domain of Oligosaccharyltransferase from Archaeoglobus fulgidus at 1.75 A Resolution
Biochemistry, 51, 2012
6J6U
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BU of 6j6u by Molmil
Rat PTPRZ D1-D2 domain
分子名称: Receptor-type tyrosine-protein phosphatase zeta
著者Sugawara, H.
登録日2019-01-15
公開日2019-08-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.32 Å)
主引用文献A head-to-toe dimerization has physiological relevance for ligand-induced inactivation of protein tyrosine receptor type Z.
J.Biol.Chem., 294, 2019
7T97
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BU of 7t97 by Molmil
Crystal structure of engineered CYS-CYS fab dimer CH1-207 (HC4)
分子名称: FAB Heavy chain, FAB Light Chain
著者Harris, S.F, Boenig, G.D.L.
登録日2021-12-18
公開日2022-10-12
実験手法X-RAY DIFFRACTION (2.144 Å)
主引用文献Antibody interfaces revealed through structural mining.
Comput Struct Biotechnol J, 20, 2022
7T99
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BU of 7t99 by Molmil
Crystal structure of engineered CYS-CYS fab dimer CL-205 (LC25)
分子名称: FAB Heavy Chain, FAB Light Chain, PHOSPHATE ION
著者Harris, S.F, Boenig, G.D.L.
登録日2021-12-18
公開日2022-10-12
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Antibody interfaces revealed through structural mining.
Comput Struct Biotechnol J, 20, 2022
7T98
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BU of 7t98 by Molmil
Crystal structure of engineered CYS-CYS fab dimer VL-108 (LC33)
分子名称: FAB Heavy Chain, FAB Light Chain
著者Harris, S.F, Boenig, G.D.L.
登録日2021-12-18
公開日2022-10-12
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Antibody interfaces revealed through structural mining.
Comput Struct Biotechnol J, 20, 2022
7DZY
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BU of 7dzy by Molmil
Spike protein from SARS-CoV2 with Fab fragment of enhancing antibody 2490
分子名称: Fab Heavy chain of enhancing antibody 2490, Fab light chain of enhancing antibody 2490, Spike glycoprotein
著者Liu, Y, Soh, W.T, Li, S, Kishikawa, J, Hirose, M, Kato, T, Standley, D, Okada, M, Arase, H.
登録日2021-01-26
公開日2021-06-02
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies.
Cell, 184, 2021
5AWX
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BU of 5awx by Molmil
Crystal structure of Human PTPRZ D1 domain
分子名称: BROMIDE ION, Receptor-type tyrosine-protein phosphatase zeta
著者Sugawara, H.
登録日2015-07-10
公開日2016-02-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Small-molecule inhibition of PTPRZ reduces tumor growth in a rat model of glioblastoma
Sci Rep, 6, 2016
7DZX
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BU of 7dzx by Molmil
Spike protein from SARS-CoV2 with Fab fragment of enhancing antibody 8D2
分子名称: Fab Heavy chain of enhancing antibody, Fab light chain of enhancing antibody, Spike glycoprotein
著者Liu, Y, Soh, W.T, Li, S, Kishikawa, J, Hirose, M, Kato, T, Standley, D, Okada, M, Arase, H.
登録日2021-01-26
公開日2021-06-02
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.53 Å)
主引用文献An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies.
Cell, 184, 2021
7DZW
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BU of 7dzw by Molmil
Apo spike protein from SARS-CoV2
分子名称: Spike glycoprotein
著者Liu, Y, Soh, W.T, Li, S, Kishikawa, J, Hirose, M, Kato, T, Standley, D, Okada, M, Arase, H.
登録日2021-01-26
公開日2021-06-02
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.45 Å)
主引用文献An infectivity-enhancing site on the SARS-CoV-2 spike protein targeted by antibodies.
Cell, 184, 2021
7WKI
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BU of 7wki by Molmil
Structure of the ultra-affinity complex between CFH and a nanobody
分子名称: Anti-CFH nanobody (VHH), Complement factor H
著者Caaveiro, J.M.M, Yokoo, T, Tsumoto, K.
登録日2022-01-10
公開日2022-11-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Antibody recognition of complement factor H reveals a flexible loop involved in atypical hemolytic uremic syndrome pathogenesis.
J.Biol.Chem., 298, 2022
5XIF
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BU of 5xif by Molmil
Crystal Structure of Prolyl-tRNA Synthetase (PRS) from Toxoplasma gondii
分子名称: CHLORIDE ION, Prolyl-tRNA synthetase (ProRS)
著者Jain, V, Manickam, Y, Sharma, A.
登録日2017-04-26
公開日2018-03-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.48 Å)
主引用文献Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis
Structure, 25, 2017
5XIQ
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Crystal Structure of Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in complex with Halofuginone
分子名称: 7-bromo-6-chloro-3-{3-[(2R,3S)-3-hydroxypiperidin-2-yl]-2-oxopropyl}quinazolin-4(3H)-one, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Jain, V, Manickam, Y, Sharma, A.
登録日2017-04-26
公開日2018-03-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Targeting Prolyl-tRNA Synthetase to Accelerate Drug Discovery against Malaria, Leishmaniasis, Toxoplasmosis, Cryptosporidiosis, and Coccidiosis
Structure, 25, 2017

 

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