2M1W

TICAM-2 TIR domain

Summary for 2M1W

• Entry DOI: 10.2210/pdb2m1w/pdb
• Related: 2M1X
• NMR Information: BMRB: 18882
• Descriptor: TIR domain-containing adapter molecule 2 (1 entity in total)
• Functional Keywords: tir domain, ticam-2, tram, innate immunity, interferon, immune system
• Biological source: Homo sapiens (human)
• Cellular location: Isoform 1: Cytoplasm. Isoform 2: Endoplasmic reticulum: Q86XR7
• Total number of polymer chains: 1
• Total formula weight: 19385.87

Authors

Enokizono, Y.,Kumeta, H.,Funami, K.,Horiuchi, M.,Sarmiento, J.,Yamashita, K.,Standley, D.M.,Matsumoto, M.,Seya, T.,Inagaki, F. (deposition date: 2012-12-07, release date: 2014-01-15, Last modification date: 2023-06-14)

• Primary citation: Enokizono, Y.,Kumeta, H.,Funami, K.,Horiuchi, M.,Sarmiento, J.,Yamashita, K.,Standley, D.M.,Matsumoto, M.,Seya, T.,Inagaki, F.; Structures and interface mapping of the TIR domain-containing adaptor molecules involved in interferon signaling.; Proc.Natl.Acad.Sci.USA, 110:19908-19913, 2013; PubMed: 24255114; DOI: 10.1073/pnas.1222811110

Experimental method

SOLUTION NMR