2G5B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2g5b by Molmil](/molmil-images/mine/2g5b) | Crystal Structure of the anti-Bax monoclonal antibody 6A7 and a Bax peptide. | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 6A7 Fab Heavy Chain, 6A7 Fab Light Chain, ... | 著者 | Peyerl, F.W, Dai, S, Murphy, G.A, Marrack, P, Kappler, J.W. | 登録日 | 2006-02-22 | 公開日 | 2006-07-25 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Elucidation of some Bax conformational changes through crystallization of an antibody-peptide complex. Cell Death Differ., 14, 2007
|
|
1PQ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1pq0 by Molmil](/molmil-images/mine/1pq0) | Crystal structure of mouse Bcl-xl | 分子名称: | Apoptosis regulator Bcl-X | 著者 | Liu, X, Dai, S, Zhu, Y, Marrack, P, Kappler, J.W. | 登録日 | 2003-06-17 | 公開日 | 2003-09-23 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The structure of a Bcl-xl/Bim fragment complex: Implications for Bim function Immunity, 19, 2003
|
|
1PQ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1pq1 by Molmil](/molmil-images/mine/1pq1) | Crystal structure of Bcl-xl/Bim | 分子名称: | Apoptosis regulator Bcl-X, BCL2-like protein 11 | 著者 | Liu, X, Dai, S, Zhu, Y, Marrack, P, Kappler, J.W. | 登録日 | 2003-06-17 | 公開日 | 2003-09-23 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | The structure of a Bcl-xl/Bim fragment complex: Implications for Bim function Immunity, 19, 2003
|
|
3RGV
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3rgv by Molmil](/molmil-images/mine/3rgv) | A single TCR bound to MHCI and MHC II reveals switchable TCR conformers | 分子名称: | Beta-2-microglobulin, H-2 class I histocompatibility antigen, K-B alpha chain, ... | 著者 | Dai, S, Huseby, E, Scott-Browne, J, Rubtsova, K, Pinilla, C, Crawford, F, Marrack, P, Yin, L, Kappler, J.W. | 登録日 | 2011-04-09 | 公開日 | 2011-07-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | A Single T Cell Receptor Bound to Major Histocompatibility Complex Class I and Class II Glycoproteins Reveals Switchable TCR Conformers. Immunity, 35, 2011
|
|
4H1L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4h1l by Molmil](/molmil-images/mine/4h1l) | TCR interaction with peptide mimics of nickel offers structural insights in nickel contact allergy | 分子名称: | Ani2.3 TCR A chain, Ani2.3 TCR B chain, HLA class II histocompatibility antigen, ... | 著者 | Kappler, J.W, Yin, L, Dai, S, Marrack, P. | 登録日 | 2012-09-10 | 公開日 | 2012-11-14 | 最終更新日 | 2013-09-04 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
4H26
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4h26 by Molmil](/molmil-images/mine/4h26) | TCR interaction with peptide mimics of nickel offers structure insight to nickel contact allergy | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ... | 著者 | Kappler, J.W, Yin, L, Dai, S, Marrack, P, Crawford, F. | 登録日 | 2012-09-12 | 公開日 | 2013-10-16 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
1IEA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1iea by Molmil](/molmil-images/mine/1iea) | HISTOCOMPATIBILITY ANTIGEN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC CLASS II I-EK | 著者 | Fremont, D.H, Hendrickson, W.A, Marrack, P, Kappler, J. | 登録日 | 1996-04-05 | 公開日 | 1997-06-05 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structures of an MHC class II molecule with covalently bound single peptides. Science, 272, 1996
|
|
4H25
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4h25 by Molmil](/molmil-images/mine/4h25) | TCR interaction with peptide mimics of nickel offers structure insights to nickel contact allergy | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DR alpha chain, ... | 著者 | Kappler, J.W, Yin, L, Dai, S, Marrack, P, Crawford, F. | 登録日 | 2012-09-12 | 公開日 | 2013-10-16 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | T-cell receptor (TCR) interaction with peptides that mimic nickel offers insight into nickel contact allergy. Proc.Natl.Acad.Sci.USA, 109, 2012
|
|
1IEB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ieb by Molmil](/molmil-images/mine/1ieb) | HISTOCOMPATIBILITY ANTIGEN | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC CLASS II I-EK, SULFATE ION | 著者 | Fremont, D.H, Hendrickson, W.A, Marrack, P, Kappler, J. | 登録日 | 1996-04-05 | 公開日 | 1997-06-05 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structures of an MHC class II molecule with covalently bound single peptides. Science, 272, 1996
|
|
1LNU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1lnu by Molmil](/molmil-images/mine/1lnu) | CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IAb BOUND TO EALPHA3K PEPTIDE | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, H-2 class II histocompatibility antigen, A beta chain, ... | 著者 | Liu, X, Dai, S, Crawford, F, Fruge, R, Marrack, P, Kappler, J. | 登録日 | 2002-05-03 | 公開日 | 2002-08-14 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Alternate interactions define the binding of peptides to the MHC molecule IA(b). Proc.Natl.Acad.Sci.USA, 99, 2002
|
|
1KTD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1ktd by Molmil](/molmil-images/mine/1ktd) | CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IEK BOUND TO PIGEON CYTOCHROME C PEPTIDE | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion protein consisting of cytochrome C peptide, glycine rich linker, ... | 著者 | Fremont, D.H, Dai, S, Chiang, H, Crawford, F, Marrack, P, Kappler, J. | 登録日 | 2002-01-15 | 公開日 | 2002-05-01 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural basis of cytochrome c presentation by IE(k). J.Exp.Med., 195, 2002
|
|
1KT2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1kt2 by Molmil](/molmil-images/mine/1kt2) | CRYSTAL STRUCTURE OF CLASS II MHC MOLECULE IEK BOUND TO MOTH CYTOCHROME C PEPTIDE | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion protein consisting of cytochrome C peptide, ... | 著者 | Fremont, D.H, Dai, S, Chiang, H, Crawford, F, Marrack, P, Kappler, J. | 登録日 | 2002-01-15 | 公開日 | 2002-05-01 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis of cytochrome c presentation by IE(k). J.Exp.Med., 195, 2002
|
|
1K8I
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1k8i by Molmil](/molmil-images/mine/1k8i) | CRYSTAL STRUCTURE OF MOUSE H2-DM | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II H2-M alpha chain, MHC class II H2-M beta 2 chain | 著者 | Fremont, D.H, Crawford, F, Marrack, P, Hendrickson, W, Kappler, J. | 登録日 | 2001-10-24 | 公開日 | 2001-12-05 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Crystal structure of mouse H2-M. Immunity, 9, 1998
|
|
4P5K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4p5k by Molmil](/molmil-images/mine/4p5k) | Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergy and Autoimmunity | 分子名称: | HLA class II histocompatibility antigen, DP alpha 1 chain, RAS peptide,HLA class II histocompatibility antigen, ... | 著者 | Clayton, G.M, Wang, Y, Crawford, F, Novikov, A, Wimberly, B.T, Kieft, J.S, Falta, M.T, Bowerman, N.A, Marrack, P, Fontenot, A.P, Dai, S, Kappler, J.W. | 登録日 | 2014-03-17 | 公開日 | 2015-01-21 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.59 Å) | 主引用文献 | Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell, 158, 2014
|
|
5UJT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5ujt by Molmil](/molmil-images/mine/5ujt) | Crystal structure of human HLA-DQ8 in complex with insulin mimotope binding in register 3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, MHC class II HLA-DQ-beta-1, ... | 著者 | Wang, Y, Dai, S. | 登録日 | 2017-01-18 | 公開日 | 2017-12-20 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
|
|
3LQZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3lqz by Molmil](/molmil-images/mine/3lqz) | Crystal Structure of HLA-DP2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, HLA class II histocompatibility antigen, DP alpha 1 chain, ... | 著者 | Dai, S. | 登録日 | 2010-02-10 | 公開日 | 2010-04-14 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Crystal structure of HLA-DP2 and implications for chronic beryllium disease. Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
5DMK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5dmk by Molmil](/molmil-images/mine/5dmk) | Crystal Structure of IAg7 in complex with RLGL-WE14 | 分子名称: | CITRATE ANION, H-2 class II histocompatibility antigen, A-D alpha chain, ... | 著者 | Wang, Y, Jin, N, Dai, S, Kappler, J.W. | 登録日 | 2015-09-08 | 公開日 | 2015-10-28 | 最終更新日 | 2016-04-06 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | N-terminal additions to the WE14 peptide of chromogranin A create strong autoantigen agonists in type 1 diabetes. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
3QI9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3qi9 by Molmil](/molmil-images/mine/3qi9) | Crystal structure of mouse CD1d-alpha-phosphotidylinositol with mouse Valpha14-Vbeta6 2A3-D NKT TCR | 分子名称: | 2-[(HYDROXY{[(2R,3R,5S,6R)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL]OXY}PHOSPHORYL)OXY]-1-[(PALMITOYLOXY)METHYL]ETHYL HEPTADECANOATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Clarke, A.J, Rossjohn, J. | 登録日 | 2011-01-26 | 公開日 | 2012-02-15 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A molecular basis for NKT cell recognition of CD1d-self-antigen Immunity, 34, 2011
|
|
6JTO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jto by Molmil](/molmil-images/mine/6jto) | Crystal structure of HLA-C05 in complex with a tumor mut10m peptide | 分子名称: | 10-mer peptide, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Bai, P, Zhou, Q, Wei, P, Lei, Y. | 登録日 | 2019-04-11 | 公開日 | 2020-04-15 | 最終更新日 | 2021-05-19 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Rational discovery of a cancer neoepitope harboring the KRAS G12D driver mutation. Sci China Life Sci, 2021
|
|
6JQ3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jq3 by Molmil](/molmil-images/mine/6jq3) | Crystal Structure of H2-Kb in complex with a DPAGT1 mutant peptide | 分子名称: | Beta-2-microglobulin, DPAGT1 mutant antigen SIIVFNLL, H-2 class I histocompatibility antigen, ... | 著者 | Bai, P, Zhou, Q, Wei, P, Yin, L. | 登録日 | 2019-03-28 | 公開日 | 2020-05-06 | 最終更新日 | 2021-02-17 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy. Oncoimmunology, 10, 2021
|
|
6JTN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jtn by Molmil](/molmil-images/mine/6jtn) | Crystal structure of HLA-C08 in complex with a tumor mut10m peptide | 分子名称: | 10-mer peptide, Beta-2-microglobulin, HLA class I antigen, ... | 著者 | Bai, P, Zhou, Q, Wei, P, Yin, L. | 登録日 | 2019-04-11 | 公開日 | 2020-04-15 | 最終更新日 | 2021-02-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy. Oncoimmunology, 10, 2021
|
|
6JTP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jtp by Molmil](/molmil-images/mine/6jtp) | Crystal structure of HLA-C08 in complex with a tumor mut9m peptide | 分子名称: | 9-mer peptide, Beta-2-microglobulin, HLA class I antigen, ... | 著者 | Bai, P, Zhou, Q, Wei, P, Lei, Y. | 登録日 | 2019-04-11 | 公開日 | 2020-04-15 | 最終更新日 | 2021-02-17 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy. Oncoimmunology, 10, 2021
|
|
1I3R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1i3r by Molmil](/molmil-images/mine/1i3r) | CRYSTAL STRUCTURE OF A MUTANT IEK CLASS II MHC MOLECULE | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FUSION PROTEIN CONSISTING OF MHC E-BETA-K PRECURSOR, ... | 著者 | Kappler, J.W, Wilson, N. | 登録日 | 2001-02-15 | 公開日 | 2001-06-20 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Mutations changing the kinetics of class II MHC peptide exchange. Immunity, 14, 2001
|
|
6JQ2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6jq2 by Molmil](/molmil-images/mine/6jq2) | Crystal Structure of H2-Kb in complex with a DPAGT1 self-peptide | 分子名称: | Beta-2-microglobulin, DPATG1 antigen SIIVFNLV, H-2 class I histocompatibility antigen, ... | 著者 | Bai, P, Yin, L. | 登録日 | 2019-03-28 | 公開日 | 2020-04-01 | 最終更新日 | 2021-02-17 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Immune-based mutation classification enables neoantigen prioritization and immune feature discovery in cancer immunotherapy. Oncoimmunology, 10, 2021
|
|
6L9K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6l9k by Molmil](/molmil-images/mine/6l9k) | H2-Ld a1a2 complexed with A5 peptide | 分子名称: | H2-Ld a1a2, SER-PRO-SER-TYR-ALA-TYR-HIS-GLN-PHE | 著者 | Wei, P.C, Yin, L. | 登録日 | 2019-11-10 | 公開日 | 2020-11-18 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structures suggest an approach for converting weak self-peptide tumor antigens into superagonists for CD8 T cells in cancer. Proc.Natl.Acad.Sci.USA, 118, 2021
|
|