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7OQT
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BU of 7oqt by Molmil
G-quadruplex structure of the C. elegans telomeric repeat: A two tetrads basket type conformation stabilised by a Hoogsteen C-T base-pair
分子名称: DNA (5'-D(*GP*GP*CP*TP*TP*AP*GP*GP*CP*TP*TP*AP*GP*GP*CP*TP*TP*AP*GP*G)-3'), POTASSIUM ION
著者Marquevielle, J, De Rache, A, Amrane, S.
登録日2021-06-04
公開日2022-06-22
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献G-quadruplex structure of the C. elegans telomeric repeat: a two tetrads basket type conformation stabilized by a non-canonical C-T base-pair.
Nucleic Acids Res., 50, 2022
6T2G
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BU of 6t2g by Molmil
NMR structure of KRAS32R G25T conformer G-quadruplex within KRAS promoter region
分子名称: KRAS32R G25T, POTASSIUM ION
著者Marquevielle, J, Salgado, G.
登録日2019-10-08
公開日2020-02-05
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Structure of two G-quadruplexes in equilibrium in the KRAS promoter.
Nucleic Acids Res., 48, 2020
7PS8
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BU of 7ps8 by Molmil
NMR Structure of the U3 RNA G-quadruplex
分子名称: POTASSIUM ION, RNA (5'-R(*CP*AP*GP*GP*GP*AP*GP*GP*UP*GP*UP*GP*GP*CP*CP*UP*GP*GP*GP*CP*GP*GP*G)-3')
著者Marquevielle, J, Amrane, S.
登録日2021-09-22
公開日2023-04-05
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献NMR Structure of the U3 RNA G-quadruplex
To Be Published
6SUU
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BU of 6suu by Molmil
NMR structure of KRAS32R G9T conformer G-quadruplex within KRAS promoter region
分子名称: KRAS32R G9T, POTASSIUM ION
著者Marquevielle, J, Salgado, G.
登録日2019-09-16
公開日2020-02-05
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献Structure of two G-quadruplexes in equilibrium in the KRAS promoter.
Nucleic Acids Res., 48, 2020
6T51
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BU of 6t51 by Molmil
NMR structure of KRAS22RT G-quadruplex forming within KRAS promoter region at physological temperature
分子名称: KRAS22RT, POTASSIUM ION
著者Marquevielle, J, Salgado, G.
登録日2019-10-15
公開日2019-10-30
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献1H,13C, and15N chemical shift assignments of a G-quadruplex forming sequence within the KRAS proto-oncogene promoter region.
Biomol.Nmr Assign., 12, 2018
7ALU
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BU of 7alu by Molmil
NMR structure of a DNA G-quadruplex containing two SP1 binding sites from HIV-1 promoter
分子名称: DNA (5'-D(*AP*GP*GP*GP*AP*GP*GP*TP*GP*TP*GP*GP*CP*CP*TP*GP*GP*GP*CP*GP*GP*G)-3'), POTASSIUM ION
著者De Rache, A, Marquevielle, J, Amrane, S.
登録日2020-10-07
公開日2022-06-01
最終更新日2023-12-13
実験手法SOLUTION NMR
主引用文献Structure of a DNA G-quadruplex that modulates SP1 binding sites architecture in HIV-1 promoter.
J.Mol.Biol., 2023
8CF2
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BU of 8cf2 by Molmil
Solution structure of the RNA helix formed by the 5'-end of U1 snRNA and an A-1 bulged 5'-splice site in complex with SMN-CY
分子名称: 4-[(3~{S})-3-ethylpiperazin-1-yl]-2-fluoranyl-~{N}-(2-methylimidazo[1,2-a]pyrazin-6-yl)benzamide, RNA (5'-R(P*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(P*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
著者Malard, F, Marquevielle, J, Campagne, S.
登録日2023-02-02
公開日2024-02-21
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The diversity of splicing modifiers acting on A-1 bulged 5'-splice sites reveals rules for rational drug design.
Nucleic Acids Res., 52, 2024
5I2V
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BU of 5i2v by Molmil
NMR structure of a new G-quadruplex forming sequence within the KRAS proto-oncogene promoter region
分子名称: DNA (5'-D(*AP*GP*GP*GP*CP*GP*GP*TP*GP*TP*GP*GP*GP*AP*AP*TP*AP*GP*GP*GP*AP*A)-3'), POTASSIUM ION
著者Salgado, G.F, Kerkour, A, Mergny, J.-L.
登録日2016-02-09
公開日2016-03-16
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献High-resolution three-dimensional NMR structure of the KRAS proto-oncogene promoter reveals key features of a G-quadruplex involved in transcriptional regulation.
J. Biol. Chem., 292, 2017
8R8P
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BU of 8r8p by Molmil
Solution structure of SMN-CX bound to the RNA helix formed upon SMN2 exon7 5'-splice site recognition
分子名称: 2-(8-fluoranyl-2-methyl-imidazo[1,2-a]pyridin-6-yl)-6-(4-methylpiperazin-1-yl)quinazoline, RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(P*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
著者Malard, F, Campagne, S.
登録日2023-11-29
公開日2024-03-06
最終更新日2024-05-22
実験手法SOLID-STATE NMR
主引用文献The diversity of splicing modifiers acting on A-1 bulged 5'-splice sites reveals rules for rational drug design.
Nucleic Acids Res., 52, 2024
8R63
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BU of 8r63 by Molmil
Solution structure of branaplam bound to the RNA duplex formed upon 5'-splice site recognition
分子名称: 5-(1~{H}-pyrazol-4-yl)-2-[6-(2,2,6,6-tetramethylpiperidin-4-yl)oxypyridazin-3-yl]phenol, RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(P*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
著者Malard, F, Campagne, S.
登録日2023-11-20
公開日2024-03-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The diversity of splicing modifiers acting on A-1 bulged 5'-splice sites reveals rules for rational drug design.
Nucleic Acids Res., 52, 2024
8R62
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BU of 8r62 by Molmil
Solution structure of Risdiplam bound to the RNA duplex formed upon 5'-splice site recognition
分子名称: 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo[1,2-b]pyridazin-6-yl)-1~{H}-pyrido[1,2-a]pyrimidin-4-one, RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3'), RNA (5'-R(P*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')
著者Malard, F, Campagne, S.
登録日2023-11-20
公開日2024-03-06
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献The diversity of splicing modifiers acting on A-1 bulged 5'-splice sites reveals rules for rational drug design.
Nucleic Acids Res., 52, 2024

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件を2024-09-11に公開中

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