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1DCQ
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BU of 1dcq by Molmil
CRYSTAL STRUCTURE OF THE ARF-GAP DOMAIN AND ANKYRIN REPEATS OF PAPBETA.
分子名称: PYK2-ASSOCIATED PROTEIN BETA, ZINC ION
著者Mandiyan, V, Andreev, J, Schlessinger, J, Hubbard, S.R.
登録日1999-11-05
公開日1999-12-22
最終更新日2016-12-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of the ARF-GAP domain and ankyrin repeats of PYK2-associated protein beta.
EMBO J., 18, 1999
2EC8
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BU of 2ec8 by Molmil
Crystal structure of the exctracellular domain of the receptor tyrosine kinase, Kit
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Mast/stem cell growth factor receptor
著者Yuzawa, S, Opatowsky, Y, Zhang, Z, Mandiyan, V, Lax, I, Schlessinger, J.
登録日2007-02-11
公開日2007-08-07
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Basis for Activation of the Receptor Tyrosine Kinase KIT by Stem Cell Factor
Cell(Cambridge,Mass.), 130, 2007
2E9W
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Crystal structure of the extracellular domain of Kit in complex with stem cell factor (SCF)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Kit ligand, Mast/stem cell growth factor receptor
著者Yuzawa, S, Opatowsky, Y, Zhang, Z, Mandiyan, V, Lax, I, Schlessinger, J.
登録日2007-01-27
公開日2007-08-07
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural Basis for Activation of the Receptor Tyrosine Kinase KIT by Stem Cell Factor
Cell(Cambridge,Mass.), 130, 2007
3JS2
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BU of 3js2 by Molmil
Crystal structure of minimal kinase domain of fibroblast growth factor receptor 1 in complex with 5-(2-thienyl)nicotinic acid
分子名称: 5-(2-thienyl)nicotinic acid, Basic fibroblast growth factor receptor 1, PHOSPHATE ION
著者Bae, J.H, Ravindranathan, K.P, Mandiyan, V, Ekkati, A.R, Schlessinger, J, Jorgensen, W.L.
登録日2009-09-09
公開日2010-02-23
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Discovery of novel fibroblast growth factor receptor 1 kinase inhibitors by structure-based virtual screening
J.Med.Chem., 53, 2010
3KXX
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Structure of the mutant Fibroblast Growth Factor receptor 1
分子名称: Basic fibroblast growth factor receptor 1
著者Bae, J.H, Boggon, T.J, Tome, F, Mandiyan, V, Lax, I, Schlessinger, J.
登録日2009-12-04
公開日2010-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Asymmetric receptor contact is required for tyrosine autophosphorylation of fibroblast growth factor receptor in living cells.
Proc.Natl.Acad.Sci.USA, 107, 2010
3KY2
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Crystal structure of Fibroblast Growth Factor Receptor 1 kinase domain
分子名称: Basic fibroblast growth factor receptor 1, SULFATE ION
著者Bae, J.H, Boggon, T.J, Tome, F, Mandiyan, V, Lax, I, Schlessinger, J.
登録日2009-12-04
公開日2010-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Asymmetric receptor contact is required for tyrosine autophosphorylation of fibroblast growth factor receptor in living cells.
Proc.Natl.Acad.Sci.USA, 107, 2010
1YXX
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Crystal Structure of Kinase Pim1 in complex with (3E)-3-[(4-HYDROXYPHENYL)IMINO]-1H-INDOL-2(3H)-ONE
分子名称: (3E)-3-[(4-HYDROXYPHENYL)IMINO]-1H-INDOL-2(3H)-ONE, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1
著者Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
登録日2005-02-22
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005
1YWV
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Crystal Structures of Proto-Oncogene Kinase Pim1: a Target of Aberrant Somatic Hypermutations in Diffuse Large Cell Lymphoma
分子名称: IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1
著者Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
登録日2005-02-18
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005
1YXU
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Crystal Structure of Kinase Pim1 in Complex with AMP
分子名称: ADENOSINE MONOPHOSPHATE, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1
著者Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
登録日2005-02-22
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.24 Å)
主引用文献Crystal Structures of Proto-oncogene Kinase Pim1: A Target of Aberrant Somatic Hypermutations in Diffuse Large Cell Lymphoma.
J.Mol.Biol., 348, 2005
1YXV
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Crystal Structure of Kinase Pim1 in complex with 3,4-Dihydroxy-1-methylquinolin-2(1H)-one
分子名称: 3,4-DIHYDROXY-1-METHYLQUINOLIN-2(1H)-ONE, IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1
著者Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
登録日2005-02-22
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structures of Proto-oncogene Kinase Pim1: A Target of Aberrant Somatic Hypermutations in Diffuse Large Cell Lymphoma.
J.Mol.Biol., 348, 2005
1YXS
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BU of 1yxs by Molmil
Crystal Structure of Kinase Pim1 with P123M mutation
分子名称: IMIDAZOLE, Proto-oncogene serine/threonine-protein kinase Pim-1
著者Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
登録日2005-02-22
公開日2005-04-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005
1YXT
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BU of 1yxt by Molmil
Crystal Structure of Kinase Pim1 in complex with AMPPNP
分子名称: PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Proto-oncogene serine/threonine-protein kinase Pim-1
著者Kumar, A, Mandiyan, V, Suzuki, Y, Zhang, C, Rice, J, Tsai, J, Artis, D.R, Ibrahim, P, Bremer, R.
登録日2005-02-22
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma.
J.Mol.Biol., 348, 2005
1IO6
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GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2 (GRB2) C-TERMINAL SH3 DOMAIN COMPLEXED WITH A LIGAND PEPTIDE (NMR, MINIMIZED MEAN STRUCTURE)
分子名称: A LIGAND PEPTIDE, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2
著者Kawasaki, M, Ogura, K, Hatanaka, H, Inagaki, F.
登録日2001-01-25
公開日2001-02-14
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution Structure of the C-Terminal SH3 Domain of Grb2 Complexed with a Ligand Peptide: A Ligand Exchange Model of the SH3 Domain
To be Published
2HSP
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SOLUTION STRUCTURE OF THE SH3 DOMAIN OF PHOSPHOLIPASE CGAMMA
分子名称: PHOSPHOLIPASE C-GAMMA (SH3 DOMAIN)
著者Kohda, D, Hatanaka, H, Odaka, M, Inagaki, F.
登録日1994-06-13
公開日1994-08-31
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of the SH3 domain of phospholipase C-gamma.
Cell(Cambridge,Mass.), 72, 1993
1HSQ
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SOLUTION STRUCTURE OF THE SH3 DOMAIN OF PHOSPHOLIPASE CGAMMA
分子名称: PHOSPHOLIPASE C-GAMMA (SH3 DOMAIN)
著者Kohda, D, Hatanaka, H, Odaka, M, Inagaki, F.
登録日1994-06-13
公開日1994-08-31
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of the SH3 domain of phospholipase C-gamma.
Cell(Cambridge,Mass.), 72, 1993
1QG1
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GROWTH FACTOR RECEPTOR BINDING PROTEIN SH2 DOMAIN COMPLEXED WITH AN SHC-DERIVED PEPTIDE
分子名称: PROTEIN (GROWTH FACTOR RECEPTOR BINDING PROTEIN), PROTEIN (SHC-DERIVED PEPTIDE)
著者Ogura, K.
登録日1999-04-19
公開日1999-04-27
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution structure of the SH2 domain of Grb2 complexed with the Shc-derived phosphotyrosine-containing peptide.
J.Mol.Biol., 289, 1999
1AQC
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X11 PTB DOMAIN-10MER PEPTIDE COMPLEX
分子名称: PEPTIDE, X11
著者Lee, C.-H, Zhang, Z, Kuriyan, J.
登録日1997-07-28
公開日1997-12-24
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain.
EMBO J., 16, 1997
1GFD
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SOLUTION STRUCTURE AND LIGAND-BINDING SITE OF THE C-TERMINAL SH3 DOMAIN OF GRB2
分子名称: GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2
著者Kohda, D, Terasawa, H, Hatanaka, H, Inagaki, F.
登録日1994-06-13
公開日1994-08-31
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2.
Structure, 2, 1994
1GCQ
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CRYSTAL STRUCTURE OF VAV AND GRB2 SH3 DOMAINS
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2, VAV PROTO-ONCOGENE
著者Nishida, M, Nagata, K, Hachimori, Y, Ogura, K, Inagaki, F.
登録日2000-08-08
公開日2001-08-08
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Novel recognition mode between Vav and Grb2 SH3 domains.
EMBO J., 20, 2001
1GFC
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SOLUTION STRUCTURE AND LIGAND-BINDING SITE OF THE C-TERMINAL SH3 DOMAIN OF GRB2
分子名称: GROWTH FACTOR RECEPTOR-BOUND PROTEIN 2
著者Kohda, D, Terasawa, H, Hatanaka, H, Inagaki, F.
登録日1994-06-13
公開日1994-08-31
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2.
Structure, 2, 1994
1GCP
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CRYSTAL STRUCTURE OF VAV SH3 DOMAIN
分子名称: VAV PROTO-ONCOGENE
著者Nishida, M, Nagata, K, Hachimori, Y, Ogura, K, Inagaki, F.
登録日2000-08-08
公開日2001-08-08
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Novel recognition mode between Vav and Grb2 SH3 domains.
EMBO J., 20, 2001
1X11
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X11 PTB DOMAIN
分子名称: 13-MER PEPTIDE, X11
著者Lee, C.-H, Zhang, Z, Kuriyan, J.
登録日1997-07-28
公開日1998-01-14
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain.
EMBO J., 16, 1997

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