4O4Y
 
 | | Crystal structure of the anti-hinge rabbit antibody 2095-2 in complex with IDES hinge peptide | | 分子名称: | 2095-2 heavy chain, 2095-2 light chain, GLYCEROL, ... | | 著者 | Malia, T.J, Teplyakov, A, Luo, J, Gilliland, G.L. | | 登録日 | 2013-12-19 | | 公開日 | 2014-03-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge.
Proteins, 82, 2014
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4O51
 | | Crystal structure of the QAA variant of anti-hinge rabbit antibody 2095-2 in complex with IDES hinge peptide | | 分子名称: | IDES hinge peptide, QAA-2095-2 heavy chain, QAA-2095-2 light chain | | 著者 | Malia, T.J, Luo, J, Teplyakov, A, Gilliland, G.L. | | 登録日 | 2013-12-19 | | 公開日 | 2014-03-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.204 Å) | | 主引用文献 | Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge.
Proteins, 82, 2014
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6XLI
 | | CRYSTAL STRUCTURE OF ANTI-TAU ANTIBODY PT3 Fab+pT212/pT217-TAU PEPTIDE | | 分子名称: | GLYCEROL, PT3 Fab Heavy Chain, PT3 Fab Light Chain, ... | | 著者 | Malia, T.J, Teplyakov, A, Luo, J. | | 登録日 | 2020-06-28 | | 公開日 | 2020-09-23 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Discovery and Functional Characterization of hPT3, a Humanized Anti-Phospho Tau Selective Monoclonal Antibody.
J Alzheimers Dis, 77, 2020
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5W06
 | | HUMAN TISSUE FACTOR IN COMPLEX WITH ANTIBODY M1587 | | 分子名称: | GLYCEROL, M1587 FAB HEAVY CHAIN, M1587 FAB LIGHT CHAIN, ... | | 著者 | Teplyakov, A, Obmolova, G, Malia, T.J, Gilliland, G.L. | | 登録日 | 2017-05-30 | | 公開日 | 2017-06-14 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural insights into humanization of anti-tissue factor antibody 10H10.
MAbs, 10, 2018
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2K4T
 | | Solution structure of human VDAC-1 in LDAO micelles | | 分子名称: | Voltage-dependent anion-selective channel protein 1 | | 著者 | Hiller, S, Garces, R.G, Malia, T.J, Orekhov, V.Y, Colombini, M, Wagner, G. | | 登録日 | 2008-06-17 | | 公開日 | 2008-09-09 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the integral human membrane protein VDAC-1 in detergent micelles.
Science, 321, 2008
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5W05
 | | ANTI-TISSUE FACTOR ANTIBODY M59, A HUMANIZED VERSION OF 10H10 | | 分子名称: | DI(HYDROXYETHYL)ETHER, M59 FAB HEAVY CHAIN, M59 FAB LIGHT CHAIN | | 著者 | Teplyakov, A, Obmolova, G, Malia, T.J, Gilliland, G.L. | | 登録日 | 2017-05-30 | | 公開日 | 2017-06-14 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | Structural insights into humanization of anti-tissue factor antibody 10H10.
MAbs, 10, 2018
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4M6A
 | | N-Terminal beta-Strand Swapping in a Consensus Derived Alternative Scaffold Driven by Stabilizing Hydrophobic Interactions | | 分子名称: | Tencon | | 著者 | Luo, J, Teplyakov, A, Obmolova, G, Malia, T.J, Chan, W, Jocobs, S.A, O'neil, K.T, Gilliland, G.L. | | 登録日 | 2013-08-09 | | 公開日 | 2014-02-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | N-terminal beta-strand swapping in a consensus-derived alternative scaffold driven by stabilizing hydrophobic interactions.
Proteins, 82, 2014
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5E2T
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5E2V
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5E2U
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5E2W
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4MA3
 | | Crystal structure of anti-hinge rabbit antibody C2095 | | 分子名称: | ACETATE ION, C2095 heavy chain, C2095 light chain, ... | | 著者 | Malia, T, Teplyakov, A, Gilliland, G.L. | | 登録日 | 2013-08-15 | | 公開日 | 2014-03-26 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure and specificity of an antibody targeting a proteolytically cleaved IgG hinge.
Proteins, 82, 2014
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3ULS
 | | Crystal structure of Fab12 | | 分子名称: | Fab12 heavy chain, Fab12 light chain | | 著者 | Luo, J, Gilliland, G.L, Obmolova, O, Malia, T, Teplyakov, A. | | 登録日 | 2011-11-11 | | 公開日 | 2012-05-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.495 Å) | | 主引用文献 | Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure.
J.Mol.Biol., 421, 2012
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5KNG
 | | CRYSTAL STRUCTURE OF ANTI-IL-13 DARPIN 6G9 | | 分子名称: | DARPIN 6G9, GLYCEROL, PHOSPHATE ION | | 著者 | Teplyakov, A, Malia, T, Obmolova, G, Gilliland, G. | | 登録日 | 2016-06-28 | | 公開日 | 2016-12-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Conformational flexibility of an anti-IL-13 DARPin.
Protein Eng. Des. Sel., 30, 2017
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5KNH
 | | CRYSTAL STRUCTURE OF DARPIN 6G9 IN COMPLEX WITH CYNO IL-13 | | 分子名称: | ACETATE ION, DARPIN 6G9, IL13 | | 著者 | Teplyakov, A, Malia, T, Obmolova, G, Gilliland, G. | | 登録日 | 2016-06-28 | | 公開日 | 2016-12-14 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Conformational flexibility of an anti-IL-13 DARPin.
Protein Eng. Des. Sel., 30, 2017
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3ULU
 | | Structure of quaternary complex of human TLR3ecd with three Fabs (Form1) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab1068 heavy chain, ... | | 著者 | Luo, J, Gilliland, G.L, Obmolova, O, Malia, T, Teplyakov, A. | | 登録日 | 2011-11-11 | | 公開日 | 2012-05-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.52 Å) | | 主引用文献 | Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure.
J.Mol.Biol., 421, 2012
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3ULV
 | | Structure of quaternary complex of human TLR3ecd with three Fabs (Form2) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab1068 heavy chain, ... | | 著者 | Luo, J, Gilliland, G.L, Obmolova, O, Malia, T, Teplyakov, A. | | 登録日 | 2011-11-11 | | 公開日 | 2012-05-23 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (3.522 Å) | | 主引用文献 | Lateral Clustering of TLR3:dsRNA Signaling Units Revealed by TLR3ecd:3Fabs Quaternary Structure.
J.Mol.Biol., 421, 2012
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5I1E
 | | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-53/IGKV1-39 | | 分子名称: | FAB HEAVY CHAIN, FAB LIGHT CHAIN, GLYCEROL, ... | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | | 登録日 | 2016-02-05 | | 公開日 | 2016-06-08 | | 最終更新日 | 2016-08-03 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural diversity in a human antibody germline library.
Mabs, 8, 2016
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5I1H
 | | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-53/IGKV3-20 | | 分子名称: | FAB HEAVY CHAIN, FAB LIGHT CHAIN, SULFATE ION | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | | 登録日 | 2016-02-05 | | 公開日 | 2016-06-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.222 Å) | | 主引用文献 | Structural diversity in a human antibody germline library.
Mabs, 8, 2016
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5I18
 | | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV1-69/IGKV4-1 | | 分子名称: | FAB HEAVY CHAIN, FAB LIGHT CHAIN, GLYCEROL | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | | 登録日 | 2016-02-05 | | 公開日 | 2016-02-24 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | | 主引用文献 | Structural diversity in a human antibody germline library.
Mabs, 8, 2016
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5I1K
 | | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV5-51/IGKV3-20 | | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, FAB HEAVY CHAIN, FAB LIGHT CHAIN, ... | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | | 登録日 | 2016-02-05 | | 公開日 | 2016-06-08 | | 最終更新日 | 2016-08-03 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural diversity in a human antibody germline library.
Mabs, 8, 2016
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5I16
 | | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV1-69/IGKV3-11 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, FAB HEAVY CHAIN, FAB LIGHT CHAIN, ... | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | | 登録日 | 2016-02-05 | | 公開日 | 2016-06-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural diversity in a human antibody germline library.
Mabs, 8, 2016
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5I1C
 | | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-23/IGKV3-20 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, FAB HEAVY CHAIN, ... | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | | 登録日 | 2016-02-05 | | 公開日 | 2016-06-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structural diversity in a human antibody germline library.
Mabs, 8, 2016
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5I1A
 | | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-23/IGKV3-11 | | 分子名称: | ACETATE ION, CNTO388 HEAVY CHAIN, CNTO388 LIGHT CHAIN, ... | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | | 登録日 | 2016-02-05 | | 公開日 | 2016-06-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structural diversity in a human antibody germline library.
Mabs, 8, 2016
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5I1G
 | | CRYSTAL STRUCTURE OF HUMAN GERMLINE ANTIBODY IGHV3-53/IGKV3-11 | | 分子名称: | FAB HEAVY CHAIN, FAB LIGHT CHAIN, SULFATE ION | | 著者 | Teplyakov, A, Obmolova, G, Malia, T, Luo, J, Gilliland, G. | | 登録日 | 2016-02-05 | | 公開日 | 2016-06-08 | | 最終更新日 | 2016-08-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural diversity in a human antibody germline library.
Mabs, 8, 2016
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