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4TRH
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BU of 4trh by Molmil
The Legionella effector SidC defines a unique family of ubiquitin ligases important for bacterial phagosomal remodeling
分子名称: SidC
著者Hsu, F.S, Luo, X, Qiu, J, Teng, Y, Jin, J, Smolka, M.B, Luo, Z.Q, Mao, Y.
登録日2014-06-16
公開日2014-07-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献The Legionella effector SidC defines a unique family of ubiquitin ligases important for bacterial phagosomal remodeling.
Proc.Natl.Acad.Sci.USA, 111, 2014
4TRG
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BU of 4trg by Molmil
the SNL domain of SidC
分子名称: MERCURY (II) ION, SidC
著者Hsu, F.S, Luo, X, Qiu, J, Teng, Y, Jin, J, Smolka, M.B, Luo, Z.Q, Mao, Y.
登録日2014-06-16
公開日2014-07-02
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献The Legionella effector SidC defines a unique family of ubiquitin ligases important for bacterial phagosomal remodeling.
Proc.Natl.Acad.Sci.USA, 111, 2014
6UMP
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BU of 6ump by Molmil
Crystal structure of MavC in complex with substrate mimic in P65 space group
分子名称: MavC, Ubiquitin, Ubiquitin-conjugating enzyme E2 N
著者Puvar, K, Iyer, S, Luo, Z.Q, Das, C.
登録日2019-10-10
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination.
Nat Commun, 11, 2020
7C0Q
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BU of 7c0q by Molmil
a Legionella pneumophila effector Lpg2505
分子名称: GLYCEROL, effector Lpg2505
著者Chen, T.T, Han, A.D, Luo, Z.Q, McCloskey, A, Perri, K.
登録日2020-05-01
公開日2021-02-24
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The metaeffector MesI regulates the activity of the Legionella effector SidI through direct protein-protein interactions.
Microbes Infect., 23, 2021
5CRC
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BU of 5crc by Molmil
Structure of the SdeA DUB Domain
分子名称: SdeA
著者Sheedlo, M.J, Qiu, J, Tan, Y, Paul, L.N, Luo, Z.Q, Das, C.
登録日2015-07-22
公開日2015-11-25
最終更新日2019-12-04
実験手法X-RAY DIFFRACTION (2.853 Å)
主引用文献Structural basis of substrate recognition by a bacterial deubiquitinase important for dynamics of phagosome ubiquitination.
Proc.Natl.Acad.Sci.USA, 112, 2015
5CRA
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BU of 5cra by Molmil
Structure of the SdeA DUB Domain
分子名称: METHYL 4-AMINOBUTANOATE, Polyubiquitin-B, SULFATE ION, ...
著者Sheedlo, M.J, Qiu, J, Luo, Z.Q, Das, C.
登録日2015-07-22
公開日2015-11-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.64 Å)
主引用文献Structural basis of substrate recognition by a bacterial deubiquitinase important for dynamics of phagosome ubiquitination.
Proc.Natl.Acad.Sci.USA, 112, 2015
5CRB
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BU of 5crb by Molmil
Crystal Structure of SdeA DUB
分子名称: SdeA
著者Sheedlo, M.J, Qiu, J, Luo, Z.Q, Das, C.
登録日2015-07-22
公開日2015-11-25
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis of substrate recognition by a bacterial deubiquitinase important for dynamics of phagosome ubiquitination.
Proc.Natl.Acad.Sci.USA, 112, 2015
4FYE
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BU of 4fye by Molmil
Crystal structure of a Legionella phosphoinositide phosphatase, SidF
分子名称: PHOSPHATE ION, SidF, inhibitor of growth family, ...
著者Hsu, F.S, Zhu, W, Brennan, L, Tao, L, Luo, Z.Q, Mao, Y.
登録日2012-07-04
公開日2012-08-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.413 Å)
主引用文献Structural basis for substrate recognition by a unique Legionella phosphoinositide phosphatase.
Proc.Natl.Acad.Sci.USA, 109, 2012
4FYF
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BU of 4fyf by Molmil
Structural basis for substrate recognition by a novel Legionella phosphoinositide phosphatase
分子名称: MERCURY (II) ION, PHOSPHATE ION, SidF, ...
著者Hsu, F.S, Zhu, W, Brennan, L, Tao, L, Luo, Z.Q, Mao, Y.
登録日2012-07-04
公開日2012-08-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.424 Å)
主引用文献Structural basis for substrate recognition by a unique Legionella phosphoinositide phosphatase.
Proc.Natl.Acad.Sci.USA, 109, 2012
4FYG
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BU of 4fyg by Molmil
Structural basis for substrate recognition by a novel Legionella phosphoinositide phosphatase
分子名称: (2R)-3-{[(S)-hydroxy{[(1S,2R,3R,4S,5S,6S)-2,3,6-trihydroxy-4,5-bis(phosphonooxy)cyclohexyl]oxy}phosphoryl]oxy}propane-1,2-diyl dibutanoate, SidF, inhibitor of growth family, ...
著者Hsu, F.S, Zhu, W, Brennan, L, Tao, L, Luo, Z.Q, Mao, Y.
登録日2012-07-04
公開日2012-08-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.822 Å)
主引用文献Structural basis for substrate recognition by a unique Legionella phosphoinositide phosphatase.
Proc.Natl.Acad.Sci.USA, 109, 2012
4ZUZ
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BU of 4zuz by Molmil
SidC 1-871
分子名称: SidC
著者Luo, X, Wasilko, D.J, Liu, Y, Sun, J, Wu, X, Luo, Z.-Q, Mao, Y.
登録日2015-05-18
公開日2015-07-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.86 Å)
主引用文献Structure of the Legionella Virulence Factor, SidC Reveals a Unique PI(4)P-Specific Binding Domain Essential for Its Targeting to the Bacterial Phagosome.
Plos Pathog., 11, 2015
6OAM
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BU of 6oam by Molmil
Crystal Structure of ChlaDUB2 DUB domain
分子名称: Deubiquitinase and deneddylase Dub2, Ubiquitin
著者Hausman, J.M, Das, C.
登録日2019-03-17
公開日2020-04-22
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.503 Å)
主引用文献The Two Deubiquitinating Enzymes fromChlamydia trachomatisHave Distinct Ubiquitin Recognition Properties.
Biochemistry, 59, 2020
6P5H
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BU of 6p5h by Molmil
Structure of MavC middle insertion domain
分子名称: MavC
著者Negron Teron, K.I, Puvar, K, Iyer, S, Das, C.
登録日2019-05-30
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination.
Nat Commun, 11, 2020
6P5B
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BU of 6p5b by Molmil
Crystal Structure of MavC in Complex with Ub-UbE2N
分子名称: MavC, Ubiquitin, Ubiquitin-conjugating enzyme E2 N
著者Puvar, K, Iyer, S, Negron Teron, K.I, Das, C.
登録日2019-05-30
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.099 Å)
主引用文献Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination.
Nat Commun, 11, 2020
5VOZ
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BU of 5voz by Molmil
Yeast V-ATPase in complex with Legionella pneumophila effector SidK (rotational state 3)
分子名称: Uncharacterized protein, V-type proton ATPase catalytic subunit A,V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, ...
著者Zhao, J.
登録日2017-05-03
公開日2017-06-28
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (7.6 Å)
主引用文献Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein.
PLoS Pathog., 13, 2017
5VOY
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BU of 5voy by Molmil
Yeast V-ATPase in complex with Legionella pneumophila effector SidK (rotational state 2)
分子名称: V-type proton ATPase catalytic subunit A,V-type proton ATPase catalytic subunit A, V-type proton ATPase subunit B, V-type proton ATPase subunit C, ...
著者Zhao, J.
登録日2017-05-03
公開日2017-06-21
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (7.9 Å)
主引用文献Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein.
PLoS Pathog., 13, 2017
6G0C
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BU of 6g0c by Molmil
Crystal structure of SdeA catalytic core
分子名称: 1,2-ETHANEDIOL, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, Ubiquitinating/deubiquitinating enzyme SdeA
著者Kalayil, S, Bhogaraju, S, Basquin, J, Dikic, I.
登録日2018-03-17
公開日2018-05-30
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.802 Å)
主引用文献Insights into catalysis and function of phosphoribosyl-linked serine ubiquitination.
Nature, 557, 2018
6WTG
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BU of 6wtg by Molmil
SdeA DUB Domain in complex with Ubiquitin
分子名称: Ubiquitin, Ubiquitinating/deubiquitinating enzyme SdeA
著者Kenny, S, Sheedlo, M, Das, C.
登録日2020-05-02
公開日2021-03-03
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.63 Å)
主引用文献Insights into Ubiquitin Product Release in Hydrolysis Catalyzed by the Bacterial Deubiquitinase SdeA.
Biochemistry, 60, 2021
8DMP
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BU of 8dmp by Molmil
Crystal structure of Legionella pneumophila macrodomain effector MavL
分子名称: MavL
著者Zhang, Z, Das, C.
登録日2022-07-08
公開日2023-07-12
最終更新日2024-07-24
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Legionella metaeffector MavL reverses ubiquitin ADP-ribosylation via a conserved arginine-specific macrodomain.
Nat Commun, 15, 2024
8DMU
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BU of 8dmu by Molmil
Crystal structure of macrodomain CG3568 from Drosophila melanogaster in complex with ADP-ribose
分子名称: CG3568, CHLORIDE ION, NICKEL (II) ION, ...
著者Zhang, Z, Das, C.
登録日2022-07-08
公開日2023-07-12
最終更新日2024-07-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Legionella metaeffector MavL reverses ubiquitin ADP-ribosylation via a conserved arginine-specific macrodomain.
Nat Commun, 15, 2024
8DMS
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BU of 8dms by Molmil
Crystal structure of Legionella pneumophila macrodomain MavL in complex with ubiquitin vinyl methyl ester soaked with ADP-ribose
分子名称: CITRATE ANION, METHYL 4-AMINOBUTANOATE, MavL, ...
著者Zhang, Z, Das, C.
登録日2022-07-08
公開日2023-07-12
最終更新日2024-07-24
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Legionella metaeffector MavL reverses ubiquitin ADP-ribosylation via a conserved arginine-specific macrodomain.
Nat Commun, 15, 2024
8DMR
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BU of 8dmr by Molmil
Legionella macrodomain effector MavL R370A in complex with ADP-ribose
分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, MavL, ...
著者Zhang, Z, Das, C.
登録日2022-07-08
公開日2023-07-12
最終更新日2024-07-24
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Legionella metaeffector MavL reverses ubiquitin ADP-ribosylation via a conserved arginine-specific macrodomain.
Nat Commun, 15, 2024
8DMQ
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BU of 8dmq by Molmil
Crystal structure of Legionella pneumophila macrodomain MavL in complex with ubiquitin vinyl methyl ester
分子名称: 1,2-ETHANEDIOL, CITRATE ANION, METHYL 4-AMINOBUTANOATE, ...
著者Zhang, Z, Das, C.
登録日2022-07-08
公開日2023-07-12
最終更新日2024-07-24
実験手法X-RAY DIFFRACTION (2.195 Å)
主引用文献Legionella metaeffector MavL reverses ubiquitin ADP-ribosylation via a conserved arginine-specific macrodomain.
Nat Commun, 15, 2024
8DMT
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BU of 8dmt by Molmil
Crystal structure of macrodomain CG2909 from Drosophila melanogaster in complex with ADP-ribose
分子名称: RE54994p, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE
著者Zhang, Z, Das, C.
登録日2022-07-08
公開日2023-08-02
最終更新日2024-07-24
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Legionella metaeffector MavL reverses ubiquitin ADP-ribosylation via a conserved arginine-specific macrodomain.
Nat Commun, 15, 2024
6B7M
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BU of 6b7m by Molmil
Crystal structure of Legionella effector sdeD (lpg2509) in complex with Ubiquitin
分子名称: Polyubiquitin-C, SdeD (lpg2509)
著者Mao, Y, Akturk, A, Wasilko, J.
登録日2017-10-04
公開日2018-04-18
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Mechanism of phosphoribosyl-ubiquitination mediated by a single Legionella effector.
Nature, 557, 2018

 

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