2O8Z
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![BU of 2o8z by Molmil](/molmil-images/mine/2o8z) | Bound Structure of CRF1 Extracellular Domain Antagonist | 分子名称: | cCRF(30-41) Peptide | 著者 | Mesleh, M.F, Shirley, W.A, Heise, C.E, Ling, N, Maki, R.A, Laura, R.P. | 登録日 | 2006-12-12 | 公開日 | 2006-12-26 | 最終更新日 | 2023-12-27 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structural characterization of a minimal peptide antagonist bound to the extracellular domain of the corticotropin-releasing factor1 receptor. J.Biol.Chem., 282, 2007
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7MF3
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![BU of 7mf3 by Molmil](/molmil-images/mine/7mf3) | Structure of the autoinhibited state of smooth muscle myosin-2 | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Myosin light polypeptide 6, ... | 著者 | Heissler, S.M, Arora, A.S, Billington, N, Sellers, J.R, Chinthalapudi, K. | 登録日 | 2021-04-08 | 公開日 | 2022-01-05 | 最終更新日 | 2024-05-29 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Cryo-EM structure of the autoinhibited state of myosin-2. Sci Adv, 7, 2021
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6FSF
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![BU of 6fsf by Molmil](/molmil-images/mine/6fsf) | Crystal structure of the tandem PX-PH-domains of Bem3 from Saccharomyces cerevisiae | 分子名称: | GTPase-activating protein BEM3 | 著者 | Ali, I, Eu, S, Koch, D, Bleimling, N, Goody, R.S, Mueller, M.P. | 登録日 | 2018-02-19 | 公開日 | 2018-05-02 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure of the tandem PX-PH domains of Bem3 from Saccharomyces cerevisiae. Acta Crystallogr F Struct Biol Commun, 74, 2018
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6ZSH
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6ZSI
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![BU of 6zsi by Molmil](/molmil-images/mine/6zsi) | The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members. | 分子名称: | DI(HYDROXYETHYL)ETHER, EH domain-binding protein 1, MAGNESIUM ION, ... | 著者 | Rai, A, Bleimling, N, Vetter, I.R, Goody, R.S. | 登録日 | 2020-07-15 | 公開日 | 2020-09-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.914 Å) | 主引用文献 | The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members. Nat Commun, 11, 2020
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6ZSJ
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![BU of 6zsj by Molmil](/molmil-images/mine/6zsj) | The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members. | 分子名称: | EH domain-binding protein 1, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... | 著者 | Rai, A, Bleimling, N, Vetter, I.R, Goody, R.S. | 登録日 | 2020-07-15 | 公開日 | 2020-09-02 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | The mechanism of activation of the actin binding protein EHBP1 by Rab8 family members. Nat Commun, 11, 2020
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4ZHX
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![BU of 4zhx by Molmil](/molmil-images/mine/4zhx) | Novel binding site for allosteric activation of AMPK | 分子名称: | (5S,6R,7R,9R,13cR,14R,16aS)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,14,15,16,16a-octahydro-5H,13cH-5,9-epoxy-4b,9a,1 5-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-ol, 3-[4-(2-hydroxyphenyl)phenyl]-4-oxidanyl-6-oxidanylidene-7H-thieno[2,3-b]pyridine-5-carbonitrile, 5'-AMP-activated protein kinase catalytic subunit alpha-2, ... | 著者 | Langendorf, C.G, Ngoei, K.R, Issa, S.M.A, Ling, N, Gorman, M.A, Parker, M.W, Sakamoto, K, Scott, J.W, Oakhill, J.S, Kemp, B.E. | 登録日 | 2015-04-27 | 公開日 | 2016-03-09 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.99 Å) | 主引用文献 | Structural basis of allosteric and synergistic activation of AMPK by furan-2-phosphonic derivative C2 binding. Nat Commun, 7, 2016
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2IH4
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![BU of 2ih4 by Molmil](/molmil-images/mine/2ih4) | |
2IH5
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7SQ1
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![BU of 7sq1 by Molmil](/molmil-images/mine/7sq1) | BG505.MD39TS Env trimer in complex with Fab from antibody C05 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C05 Fab Light chain, ... | 著者 | Moore, A, Du, J, Xu, Z, Walker, S, Kulp, D.W, Pallesen, J. | 登録日 | 2021-11-04 | 公開日 | 2022-06-22 | 最終更新日 | 2022-12-07 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Induction of tier-2 neutralizing antibodies in mice with a DNA-encoded HIV envelope native like trimer. Nat Commun, 13, 2022
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1AQJ
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5N8Y
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![BU of 5n8y by Molmil](/molmil-images/mine/5n8y) | KaiCBA circadian clock backbone model based on a Cryo-EM density | 分子名称: | Circadian clock protein KaiA, Circadian clock protein KaiB, Circadian clock protein kinase KaiC | 著者 | Schuller, J.M, Snijder, J, Loessl, P, Heck, A.J.R, Foerster, F. | 登録日 | 2017-02-24 | 公開日 | 2017-03-29 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4.7 Å) | 主引用文献 | Structures of the cyanobacterial circadian oscillator frozen in a fully assembled state. Science, 355, 2017
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8D8R
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![BU of 8d8r by Molmil](/molmil-images/mine/8d8r) | SARS-CoV-2 Spike RBD in complex with DMAb 2196 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2196 heavy chain, 2196 light chain, ... | 著者 | Du, J, Cui, J, Pallesen, J. | 登録日 | 2022-06-08 | 公開日 | 2022-10-19 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2. Nat Commun, 13, 2022
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8D8Q
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![BU of 8d8q by Molmil](/molmil-images/mine/8d8q) | SARS-CoV-2 Spike RBD in complex with DMAbs 2130 and 2196 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2130 heavy chain, 2130 light chain, ... | 著者 | Du, J, Cui, J, Pallesen, J. | 登録日 | 2022-06-08 | 公開日 | 2022-10-19 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | DNA-delivered antibody cocktail exhibits improved pharmacokinetics and confers prophylactic protection against SARS-CoV-2. Nat Commun, 13, 2022
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8F5K
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8F5L
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![BU of 8f5l by Molmil](/molmil-images/mine/8f5l) | Azurin from Pseudomonas aeruginosa, Y72F/Y108F/F110L mutant | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Azurin, COPPER (II) ION | 著者 | Zeug, M, Offenbacher, A.R, Choe, J. | 登録日 | 2022-11-14 | 公開日 | 2023-01-04 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.15 Å) | 主引用文献 | Electrochemical and Structural Study of the Buried Tryptophan in Azurin: Effects of Hydration and Polarity on the Redox Potential of W48. J.Phys.Chem.B, 127, 2023
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8A4C
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![BU of 8a4c by Molmil](/molmil-images/mine/8a4c) | Structure of human Rep15:Rab3B complex. | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Rab15 effector protein, ... | 著者 | Rai, A, Vetter, I.R, Goody, R.S. | 登録日 | 2022-06-10 | 公開日 | 2022-08-10 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector. Nat Commun, 13, 2022
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8A4B
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![BU of 8a4b by Molmil](/molmil-images/mine/8a4b) | Structure of human Rep15:Rab3B_Q81L complex. | 分子名称: | GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Rab15 effector protein, ... | 著者 | Rai, A, Vetter, I.R, Goody, R.S. | 登録日 | 2022-06-10 | 公開日 | 2022-08-10 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector. Nat Commun, 13, 2022
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8A4A
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![BU of 8a4a by Molmil](/molmil-images/mine/8a4a) | Structure of human Rep15 in complex with bovine Rab3C. | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Rab15 effector protein, ... | 著者 | Rai, A, Vetter, I.R, Goody, R.S. | 登録日 | 2022-06-10 | 公開日 | 2022-08-10 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Rep15 interacts with several Rab GTPases and has a distinct fold for a Rab effector. Nat Commun, 13, 2022
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6TO4
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6TOE
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6S8Z
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2ADM
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![BU of 2adm by Molmil](/molmil-images/mine/2adm) | ADENINE-N6-DNA-METHYLTRANSFERASE TAQI | 分子名称: | ADENINE-N6-DNA-METHYLTRANSFERASE TAQI, S-ADENOSYLMETHIONINE | 著者 | Schluckebier, G, Saenger, W. | 登録日 | 1996-07-15 | 公開日 | 1997-01-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI. J.Mol.Biol., 265, 1997
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7Z9P
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![BU of 7z9p by Molmil](/molmil-images/mine/7z9p) | The novel DNA binding mechanism of ridinilazole, a precision Clostridiodes difficile antibiotic | 分子名称: | DNA (5'-D(P*GP*CP*GP*AP*AP*TP*TP*CP*GP*CP*G*(RID))-3'), Ridinilazole, SODIUM ION, ... | 著者 | Mason, S, Leonard, P.M. | 登録日 | 2022-03-21 | 公開日 | 2023-03-29 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Novel DNA Binding Mechanism of Ridinilazole, a Precision Clostridiodes difficile Antibiotic. Antimicrob.Agents Chemother., 67, 2023
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1AQI
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![BU of 1aqi by Molmil](/molmil-images/mine/1aqi) | STRUCTURE OF ADENINE-N6-DNA-METHYLTRANSFERASE TAQI | 分子名称: | ADENINE-N6-DNA-METHYLTRANSFERASE TAQI, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Schluckebier, G, Saenger, W. | 登録日 | 1996-07-25 | 公開日 | 1997-02-12 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Differential binding of S-adenosylmethionine S-adenosylhomocysteine and Sinefungin to the adenine-specific DNA methyltransferase M.TaqI. J.Mol.Biol., 265, 1997
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