8BXW
| Crystal structure of Odorant Binding Protein 5 from Anopheles gambiae (AgamOBP5) with Carvacrol | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1-BUTANOL, 2-methyl-5-propan-2-yl-phenol, ... | 著者 | Liggri, P.G.V, Tsitsanou, K.E, Zographos, S.E. | 登録日 | 2022-12-10 | 公開日 | 2023-03-22 | 最終更新日 | 2023-04-12 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | The structure of AgamOBP5 in complex with the natural insect repellents Carvacrol and Thymol: Crystallographic, fluorescence and thermodynamic binding studies. Int.J.Biol.Macromol., 237, 2023
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8BXU
| Crystal structure of Odorant Binding Protein 5 from Anopheles gambiae (AgamOBP5) with MPD (2-Methyl-2,4-pentanediol) | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-ETHOXYETHANOL, Odorant binding protein, ... | 著者 | Liggri, P.G.V, Tsitsanou, K.E, Zographos, S.E. | 登録日 | 2022-12-09 | 公開日 | 2023-03-22 | 最終更新日 | 2023-04-12 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | The structure of AgamOBP5 in complex with the natural insect repellents Carvacrol and Thymol: Crystallographic, fluorescence and thermodynamic binding studies. Int.J.Biol.Macromol., 237, 2023
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8BXV
| Crystal structure of Odorant Binding Protein 5 from Anopheles gambiae (AgamOBP5) with Thymol | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 5-METHYL-2-(1-METHYLETHYL)PHENOL, DI(HYDROXYETHYL)ETHER, ... | 著者 | Liggri, P.G.V, Tsitsanou, K.E, Zographos, S.E. | 登録日 | 2022-12-10 | 公開日 | 2023-03-22 | 最終更新日 | 2023-04-12 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | The structure of AgamOBP5 in complex with the natural insect repellents Carvacrol and Thymol: Crystallographic, fluorescence and thermodynamic binding studies. Int.J.Biol.Macromol., 237, 2023
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8BY4
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5MCB
| Glycogen phosphorylase in complex with chlorogenic acid. | 分子名称: | Chlorogenic acid, Glycogen phosphorylase, muscle form, ... | 著者 | Leonidas, D.D, Stravodimos, G.A, Kyriakis, E, Chatzileontiadou, D.S.M, Kantsadi, A.L. | 登録日 | 2016-11-09 | 公開日 | 2017-09-20 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Affinity Crystallography Reveals the Bioactive Compounds of Industrial Juicing Byproducts of Punica granatum for Glycogen Phosphorylase. Curr Drug Discov Technol, 15, 2018
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8C6G
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8C68
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8C6E
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6QA7
| Glycogen Phosphorylase b in complex with 29 | 分子名称: | (5~{S},7~{R},8~{S},9~{S},10~{R})-7-(hydroxymethyl)-2-naphthalen-1-yl-8,9,10-tris(oxidanyl)-6-oxa-1,3-diazaspiro[4.5]dec-1-en-4-one, Glycogen phosphorylase, muscle form, ... | 著者 | Kyriakis, E, Stravodimos, G.A, Skamnaki, V.T, Leonidas, D.D. | 登録日 | 2018-12-18 | 公開日 | 2019-06-26 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Glucopyranosylidene-spiro-imidazolinones, a New Ring System: Synthesis and Evaluation as Glycogen Phosphorylase Inhibitors by Enzyme Kinetics and X-ray Crystallography. J.Med.Chem., 62, 2019
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6QA6
| Glycogen Phosphorylase b in complex with 30 | 分子名称: | (5~{S},7~{R},8~{S},9~{S},10~{R})-7-(hydroxymethyl)-2-naphthalen-2-yl-8,9,10-tris(oxidanyl)-6-oxa-1,3-diazaspiro[4.5]dec-1-en-4-one, DIMETHYL SULFOXIDE, Glycogen phosphorylase, ... | 著者 | Kyriakis, E, Stravodimos, G.A, Skamnaki, V.T, Leonidas, D.D. | 登録日 | 2018-12-18 | 公開日 | 2019-06-26 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Glucopyranosylidene-spiro-imidazolinones, a New Ring System: Synthesis and Evaluation as Glycogen Phosphorylase Inhibitors by Enzyme Kinetics and X-ray Crystallography. J.Med.Chem., 62, 2019
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6QA8
| Glycogen Phosphorylase b in complex with 28 | 分子名称: | (5~{S},7~{R},8~{S},9~{S},10~{R})-7-(hydroxymethyl)-8,9,10-tris(oxidanyl)-2-phenyl-6-oxa-1,3-diazaspiro[4.5]dec-1-en-4-one, Glycogen phosphorylase, muscle form, ... | 著者 | Kyriakis, E, Stravodimos, G.A, Skamnaki, V.T, Leonidas, D.D. | 登録日 | 2018-12-18 | 公開日 | 2019-06-26 | 最終更新日 | 2019-07-24 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Glucopyranosylidene-spiro-imidazolinones, a New Ring System: Synthesis and Evaluation as Glycogen Phosphorylase Inhibitors by Enzyme Kinetics and X-ray Crystallography. J.Med.Chem., 62, 2019
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6R0H
| Glycogen Phosphorylase b in complex with 3 | 分子名称: | 3-(4-fluorophenyl)-~{N}-[(2~{R},3~{R},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]benzamide, Glycogen phosphorylase, muscle form, ... | 著者 | Tsagkarakou, S.A, Koulas, M.S, Kyriakis, E, Stravodimos, G.A, Skamnaki, V.T, Leonidas, D.D. | 登録日 | 2019-03-13 | 公開日 | 2019-04-10 | 最終更新日 | 2019-04-24 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | High Consistency of Structure-Based Design and X-Ray Crystallography: Design, Synthesis, Kinetic Evaluation and Crystallographic Binding Mode Determination of Biphenyl-N-acyl-beta-d-Glucopyranosylamines as Glycogen Phosphorylase Inhibitors. Molecules, 24, 2019
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6R0I
| Glycogen Phosphorylase b in complex with 4 | 分子名称: | Glycogen phosphorylase, muscle form, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Koulas, M.S, Tsagkarakou, S.A, Kyriakis, E, Stravodimos, G.A, Skamnaki, V.T, Leonidas, D.D. | 登録日 | 2019-03-13 | 公開日 | 2019-04-17 | 最終更新日 | 2019-04-24 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | High Consistency of Structure-Based Design and X-Ray Crystallography: Design, Synthesis, Kinetic Evaluation and Crystallographic Binding Mode Determination of Biphenyl-N-acyl-beta-d-Glucopyranosylamines as Glycogen Phosphorylase Inhibitors. Molecules, 24, 2019
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6S51
| The crystal structure of glycogen phosphorylase in complex with 10 | 分子名称: | (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(2-phenyl-1,3-thiazol-4-yl)oxane-3,4,5-triol, Glycogen phosphorylase, muscle form, ... | 著者 | Kyriakis, E, Solovou, T.G.A, Papaioannou, O.S.E, Skamnaki, V.T, Leonidas, D.D. | 登録日 | 2019-06-29 | 公開日 | 2020-02-19 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | The architecture of hydrogen and sulfur sigma-hole interactions explain differences in the inhibitory potency of C-beta-d-glucopyranosyl thiazoles, imidazoles and an N-beta-d glucopyranosyl tetrazole for human liver glycogen phosphorylase and offer new insights to structure-based design. Bioorg.Med.Chem., 28, 2020
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6S4H
| The crystal structure of glycogen phosphorylase in complex with 8 | 分子名称: | (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(2-phenyl-1~{H}-imidazol-4-yl)oxane-3,4,5-triol, DIMETHYL SULFOXIDE, Glycogen phosphorylase, ... | 著者 | Kyriakis, E, Solovou, T.G.A, Papaioannou, O.S.E, Skamnaki, V.T, Leonidas, D.D. | 登録日 | 2019-06-28 | 公開日 | 2020-02-19 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | The architecture of hydrogen and sulfur sigma-hole interactions explain differences in the inhibitory potency of C-beta-d-glucopyranosyl thiazoles, imidazoles and an N-beta-d glucopyranosyl tetrazole for human liver glycogen phosphorylase and offer new insights to structure-based design. Bioorg.Med.Chem., 28, 2020
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6S52
| The crystal structure of glycogen phosphorylase in complex with 14 | 分子名称: | (2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-(5-phenyl-1,2,3,4-tetrazol-2-yl)oxane-3,4,5-triol, Glycogen phosphorylase, muscle form, ... | 著者 | Kyriakis, E, Solovou, T.G.A, Papaioannou, O.S.E, Skamnaki, V.T, Leonidas, D.D. | 登録日 | 2019-06-29 | 公開日 | 2020-02-19 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | The architecture of hydrogen and sulfur sigma-hole interactions explain differences in the inhibitory potency of C-beta-d-glucopyranosyl thiazoles, imidazoles and an N-beta-d glucopyranosyl tetrazole for human liver glycogen phosphorylase and offer new insights to structure-based design. Bioorg.Med.Chem., 28, 2020
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6S4P
| The crystal structure of glycogen phosphorylase in complex with 13 | 分子名称: | (2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-(4-naphthalen-2-yl-1,3-thiazol-2-yl)oxane-3,4,5-triol, Glycogen phosphorylase, muscle form, ... | 著者 | Kyriakis, E, Solovou, T.G.A, Papaioannou, O.S.E, Skamnaki, V.T, Leonidas, D.D. | 登録日 | 2019-06-28 | 公開日 | 2020-02-19 | 実験手法 | X-RAY DIFFRACTION (2.37 Å) | 主引用文献 | The architecture of hydrogen and sulfur sigma-hole interactions explain differences in the inhibitory potency of C-beta-d-glucopyranosyl thiazoles, imidazoles and an N-beta-d glucopyranosyl tetrazole for human liver glycogen phosphorylase and offer new insights to structure-based design. Bioorg.Med.Chem., 28, 2020
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6S4K
| The crystal structure of glycogen phosphorylase in complex with 12 | 分子名称: | (2~{R},3~{S},4~{S},5~{R},6~{R})-2-(hydroxymethyl)-6-(4-phenyl-1,3-thiazol-2-yl)oxane-3,4,5-triol, Glycogen phosphorylase, muscle form, ... | 著者 | Kyriakis, E, Solovou, T.G.A, Papaioannou, O.S.E, Skamnaki, V.T, Leonidas, D.D. | 登録日 | 2019-06-28 | 公開日 | 2020-02-19 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | The architecture of hydrogen and sulfur sigma-hole interactions explain differences in the inhibitory potency of C-beta-d-glucopyranosyl thiazoles, imidazoles and an N-beta-d glucopyranosyl tetrazole for human liver glycogen phosphorylase and offer new insights to structure-based design. Bioorg.Med.Chem., 28, 2020
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6S4O
| The crystal structure of glycogen phosphorylase in complex with 9 | 分子名称: | (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(2-naphthalen-2-yl-1~{H}-imidazol-4-yl)oxane-3,4,5-triol, Glycogen phosphorylase, muscle form, ... | 著者 | Kyriakis, E, Solovou, T.G.A, Papaioannou, O.S.E, Skamnaki, V.T, Leonidas, D.D. | 登録日 | 2019-06-28 | 公開日 | 2020-02-19 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | The architecture of hydrogen and sulfur sigma-hole interactions explain differences in the inhibitory potency of C-beta-d-glucopyranosyl thiazoles, imidazoles and an N-beta-d glucopyranosyl tetrazole for human liver glycogen phosphorylase and offer new insights to structure-based design. Bioorg.Med.Chem., 28, 2020
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6S4R
| The crystal structure of glycogen phosphorylase in complex with 11 | 分子名称: | (2~{R},3~{S},4~{R},5~{R},6~{S})-2-(hydroxymethyl)-6-(2-naphthalen-2-yl-1,3-thiazol-4-yl)oxane-3,4,5-triol, Glycogen phosphorylase, muscle form, ... | 著者 | Kyriakis, E, Papaioannou, O.S.E, Solovou, T.G.A, Skamnaki, V.T, Leonidas, D.D. | 登録日 | 2019-06-28 | 公開日 | 2020-02-19 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | The architecture of hydrogen and sulfur sigma-hole interactions explain differences in the inhibitory potency of C-beta-d-glucopyranosyl thiazoles, imidazoles and an N-beta-d glucopyranosyl tetrazole for human liver glycogen phosphorylase and offer new insights to structure-based design. Bioorg.Med.Chem., 28, 2020
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