5MCB

Glycogen phosphorylase in complex with chlorogenic acid.

Summary for 5MCB

Entry DOI	10.2210/pdb5mcb/pdb
Descriptor	Glycogen phosphorylase, muscle form, PYRIDOXAL-5'-PHOSPHATE, Chlorogenic acid, ... (4 entities in total)
Functional Keywords	alpha and beta protein, transferase
Biological source	Oryctolagus cuniculus (Rabbit)
Total number of polymer chains	1
Total formula weight	95882.37
Authors	Leonidas, D.D.,Stravodimos, G.A.,Kyriakis, E.,Chatzileontiadou, D.S.M.,Kantsadi, A.L. (deposition date: 2016-11-09, release date: 2017-09-20, Last modification date: 2024-01-17)
Primary citation	Stravodimos, G.A.,Kantsadi, A.L.,Apostolou, A.,Kyriakis, E.,Kafaski-Kanelli, V.N.,Solovou, T.,Gatzona, P.,Liggri, P.G.V.,Theofanous, S.,Gorgogietas, V.A.,Kissa, A.,Psachoula, C.,Lemonakis, A.,Chatzileontiadou, D.S.M.,Psarra, A.G.,Skamnaki, V.T.,Haroutounian, S.A.,Leonidas, D.D. Affinity Crystallography Reveals the Bioactive Compounds of Industrial Juicing Byproducts of Punica granatum for Glycogen Phosphorylase. Curr Drug Discov Technol, 15:41-53, 2018 Cited by PubMed Abstract: Glycogen phosphorylase (GP) is a pharmaceutical target for the discovery of new antihyperglycaemic agents. Punica granatum is a well-known plant for its potent antioxidant and antimicrobial activities but so far has not been examined for antihyperglycaemic activity. PubMed: 28625148 DOI: 10.2174/1570163814666170619091736 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation