3BYD
 
 | | Crystal structure of beta-lactamase OXY-1-1 from Klebsiella oxytoca | | 分子名称: | ACETATE ION, Beta-lactamase OXY-1, SULFATE ION | | 著者 | Liang, Y.-H, Wu, S.W, Su, X.-D. | | 登録日 | 2008-01-15 | | 公開日 | 2009-01-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Structural insights into the broadened substrate profile of the extended-spectrum beta-lactamase OXY-1-1 from Klebsiella oxytoca
Acta Crystallogr.,Sect.D, 68, 2012
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2BAZ
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2G0I
 | | Crystal structure of SMU.848 from Streptococcus mutans | | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, hypothetical protein SMU.848 | | 著者 | Hou, H.-F, Gao, Z.-Q, Li, L.-F, Liang, Y.-H, Su, X.-D, Dong, Y.-H. | | 登録日 | 2006-02-13 | | 公開日 | 2006-08-08 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Crystal structure of SMU.848 from Streptococcus mutans
To be Published
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2G0J
 | | Crystal structure of SMU.848 from Streptococcus mutans | | 分子名称: | hypothetical protein SMU.848 | | 著者 | Hou, H.-F, Gao, Z.-Q, Li, L.-F, Liang, Y.-H, Su, X.-D, Dong, Y.-H. | | 登録日 | 2006-02-13 | | 公開日 | 2006-08-08 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of SMU.848 from Streptococcus mutans
To be Published
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2FKN
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4JQU
 | | Crystal structure of Ubc7p in complex with the U7BR of Cue1p | | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Coupling of ubiquitin conjugation to ER degradation protein 1, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Liang, Y.-H, Metzger, M.B, Weissman, A.M, Ji, X. | | 登録日 | 2013-03-20 | | 公開日 | 2013-05-29 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | | 主引用文献 | A Structurally Unique E2-Binding Domain Activates Ubiquitination by the ERAD E2, Ubc7p, through Multiple Mechanisms.
Mol.Cell, 50, 2013
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7LEW
 | | Crystal structure of UBE2G2 in complex with the UBE2G2-binding region of AUP1 | | 分子名称: | Lipid droplet-regulating VLDL assembly factor AUP1, Ubiquitin-conjugating enzyme E2 G2 | | 著者 | Liang, Y.-H, Smith, C.E, Tsai, Y.C, Weissman, A.M, Ji, X. | | 登録日 | 2021-01-15 | | 公開日 | 2021-11-10 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.736 Å) | | 主引用文献 | A structurally conserved site in AUP1 binds the E2 enzyme UBE2G2 and is essential for ER-associated degradation.
Plos Biol., 19, 2021
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1FAW
 | | GRAYLAG GOOSE HEMOGLOBIN (OXY FORM) | | 分子名称: | HEMOGLOBIN (ALPHA SUBUNIT), HEMOGLOBIN (BETA SUBUNIT), OXYGEN MOLECULE, ... | | 著者 | Liang, Y.-H, Liu, X.-Z, Liu, S.-H, Lu, G.-Y. | | 登録日 | 2000-07-13 | | 公開日 | 2001-12-05 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | | 主引用文献 | The structure of greylag goose oxy haemoglobin: the roles of four mutations compared with bar-headed goose haemoglobin.
Acta Crystallogr.,Sect.D, 57, 2001
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5D1L
 | | Crystal Structure of UbcH5B in Complex with the RING-U5BR Fragment of AO7 (Y165A) | | 分子名称: | DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase RNF25, OXALATE ION, ... | | 著者 | Liang, Y.-H, Li, S, Weissman, A.M, Ji, X. | | 登録日 | 2015-08-04 | | 公開日 | 2015-10-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.618 Å) | | 主引用文献 | Insights into Ubiquitination from the Unique Clamp-like Binding of the RING E3 AO7 to the E2 UbcH5B.
J.Biol.Chem., 290, 2015
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5D1M
 | | Crystal Structure of UbcH5B in Complex with the RING-U5BR Fragment of AO7 (P199A) | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase RNF25, ... | | 著者 | Liang, Y.-H, Li, S, Weissman, A.M, Ji, X. | | 登録日 | 2015-08-04 | | 公開日 | 2015-10-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.581 Å) | | 主引用文献 | Insights into Ubiquitination from the Unique Clamp-like Binding of the RING E3 AO7 to the E2 UbcH5B.
J.Biol.Chem., 290, 2015
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5D1K
 | | Crystal Structure of UbcH5B in Complex with the RING-U5BR Fragment of AO7 | | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase RNF25, ... | | 著者 | Liang, Y.-H, Li, S, Weissman, A.M, Ji, X. | | 登録日 | 2015-08-04 | | 公開日 | 2015-10-28 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Insights into Ubiquitination from the Unique Clamp-like Binding of the RING E3 AO7 to the E2 UbcH5B.
J.Biol.Chem., 290, 2015
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4LAD
 | | Crystal Structure of the Ube2g2:RING-G2BR complex | | 分子名称: | E3 ubiquitin-protein ligase AMFR, OXALATE ION, Ubiquitin-conjugating enzyme E2 G2, ... | | 著者 | Liang, Y.-H, Li, J, Das, R, Byrd, R.A, Ji, X. | | 登録日 | 2013-06-19 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Allosteric regulation of E2:E3 interactions promote a processive ubiquitination machine.
Embo J., 32, 2013
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4OOG
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4M2Z
 | | Crystal structure of RNASE III complexed with double-stranded RNA and CMP (TYPE II CLEAVAGE) | | 分子名称: | CYTIDINE-5'-MONOPHOSPHATE, MAGNESIUM ION, RNA10, ... | | 著者 | Gan, J, Liang, Y.-H, Shaw, G.X, Tropea, J.E, Waugh, D.S, Ji, X. | | 登録日 | 2013-08-05 | | 公開日 | 2013-12-11 | | 最終更新日 | 2024-07-03 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | RNase III: Genetics and Function; Structure and Mechanism.
Annu. Rev. Genet., 47, 2013
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4M30
 | | Crystal structure of RNASE III complexed with double-stranded RNA AND AMP (TYPE II CLEAVAGE) | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ADENOSINE MONOPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Gan, J, Liang, Y.-H, Shaw, G.X, Tropea, J.E, Waugh, D.S, Ji, X. | | 登録日 | 2013-08-05 | | 公開日 | 2013-12-11 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | | 主引用文献 | RNase III: Genetics and Function; Structure and Mechanism.
Annu. Rev. Genet., 47, 2013
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3CXP
 | | Crystal structure of human glucosamine 6-phosphate N-acetyltransferase 1 mutant E156A | | 分子名称: | CHLORIDE ION, Glucosamine 6-phosphate N-acetyltransferase | | 著者 | Wang, J, Liu, X, Li, L.-F, Su, X.-D. | | 登録日 | 2008-04-25 | | 公開日 | 2008-09-16 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Acceptor substrate binding revealed by crystal structure of human glucosamine-6-phosphate N-acetyltransferase 1
Febs Lett., 582, 2008
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3CXQ
 | | Crystal structure of human glucosamine 6-phosphate N-acetyltransferase 1 bound to GlcN6P | | 分子名称: | 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, Glucosamine 6-phosphate N-acetyltransferase | | 著者 | Wang, J, Liu, X, Li, L.-F, Su, X.-D. | | 登録日 | 2008-04-25 | | 公開日 | 2008-09-16 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Acceptor substrate binding revealed by crystal structure of human glucosamine-6-phosphate N-acetyltransferase 1
Febs Lett., 582, 2008
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3CXS
 | | Crystal structure of human GNA1 | | 分子名称: | Glucosamine 6-phosphate N-acetyltransferase | | 著者 | Wang, J, Liu, X, Li, L.-F, Su, X.-D. | | 登録日 | 2008-04-25 | | 公開日 | 2008-09-16 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Acceptor substrate binding revealed by crystal structure of human glucosamine-6-phosphate N-acetyltransferase 1
Febs Lett., 582, 2008
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7KDO
 | | Crystal structure of Escherichia coli HPPK in complex with bisubstrate inhibitor HP-73 | | 分子名称: | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 5'-S-[(2R,4R)-1-{2-[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridine-6-carbonyl)amino]ethyl}-2-carboxypiperidin-4-yl]-5'-thioadenosine | | 著者 | Shaw, G.X, Shi, G, Ji, X. | | 登録日 | 2020-10-09 | | 公開日 | 2020-12-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Bisubstrate inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: Transition state analogs for high affinity binding.
Bioorg.Med.Chem., 29, 2021
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7KDR
 | | Crystal structure of Escherichia coli HPPK in complex with bisubstrate inhibitor HP-75 | | 分子名称: | 1,2-ETHANEDIOL, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 5'-{[(2R,4R)-1-{2-[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridine-6-carbonyl)amino]ethyl}-2-carboxypiperidin-4-yl]sulfonyl}-5'-deoxyadenosine, ... | | 著者 | Shaw, G.X, Shi, G, Ji, X. | | 登録日 | 2020-10-09 | | 公開日 | 2020-12-02 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.488 Å) | | 主引用文献 | Bisubstrate inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase: Transition state analogs for high affinity binding.
Bioorg.Med.Chem., 29, 2021
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6AN6
 | | Crystal structure of Escherichia coli HPPK in complex with bisubstrate analogue inhibitor HP-72 | | 分子名称: | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 5'-S-{2-[{2-[(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridine-6-carbonyl)amino]ethyl}(phosphonomethyl)amino]ethyl}-5'-thioadenosine | | 著者 | Shaw, G.X, Shi, G, Ji, X. | | 登録日 | 2017-08-12 | | 公開日 | 2018-08-15 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Bisubstrate analogue inhibitors of HPPK: Transition state mimetics
to be published
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6AN4
 | | Crystal structure of Escherichia coli HPPK in complex with bisubstrate analogue inhibitor HP-39 (J1F) | | 分子名称: | ((2-(2-amino-7,7-dimethyl-4-oxo-3,4,7,8-tetrahydropteridine-6-carboxamido)-N-(2-((((2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)amino)-2-oxoethyl)acetamido)methyl)phosphonic acid, 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, CHLORIDE ION | | 著者 | Shaw, G.X, Shi, G, Ji, X. | | 登録日 | 2017-08-12 | | 公開日 | 2018-08-15 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | | 主引用文献 | Bisubstrate analog inhibitors of HPPK: Transition state mimetics
to be published
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