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6FTO
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BU of 6fto by Molmil
Crystal structure of the Chp2 chromoshadow domain in complex with N-terminal domain of chromatin remodeler Mit1
分子名称: Chromatin remodeling factor mit1, Chromo domain-containing protein 2, HEXANE-1,6-DIOL
著者Leopold, K, Schalch, T.
登録日2018-02-22
公開日2019-03-27
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Transcriptional gene silencing requires dedicated interaction between HP1 protein Chp2 and chromatin remodeler Mit1.
Genes Dev., 33, 2019
7MJI
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BU of 7mji by Molmil
Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to VH ab8 (focused refinement of RBD and VH ab8)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, VH ab8
著者Zhu, X, Mannar, D, Srivastava, S.S, Berezuk, A.M, Demers, J.P, Saville, J.W, Leopold, K, Li, W, Dimitrov, D.S, Tuttle, K.S, Zhou, S, Chittori, S, Subramaniam, S.
登録日2021-04-20
公開日2021-05-12
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies.
Plos Biol., 19, 2021
7MJH
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BU of 7mjh by Molmil
Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to VH ab8
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ...
著者Zhu, X, Mannar, D, Srivastava, S.S, Berezuk, A.M, Demers, J.P, Saville, J.W, Leopold, K, Li, W, Dimitrov, D.S, Tuttle, K.S, Zhou, S, Chittori, S, Subramaniam, S.
登録日2021-04-20
公開日2021-05-12
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (2.66 Å)
主引用文献Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies.
Plos Biol., 19, 2021
7MJJ
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BU of 7mjj by Molmil
Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to Fab ab1 (class 1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab ab1 Heavy Chain, ...
著者Zhu, X, Mannar, D, Srivastava, S.S, Berezuk, A.M, Demers, J.P, Saville, J.W, Leopold, K, Li, W, Dimitrov, D.S, Tuttle, K.S, Zhou, S, Chittori, S, Subramaniam, S.
登録日2021-04-20
公開日2021-05-12
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.32 Å)
主引用文献Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies.
Plos Biol., 19, 2021
7MJL
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BU of 7mjl by Molmil
Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to Fab ab1 (focused refinement of RBD and Fab ab1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab ab1 Heavy Chain, Fab ab1 Light Chain, ...
著者Zhu, X, Mannar, D, Srivastava, S.S, Berezuk, A.M, Demers, J.P, Saville, J.W, Leopold, K, Li, W, Dimitrov, D.S, Tuttle, K.S, Zhou, S, Chittori, S, Subramaniam, S.
登録日2021-04-20
公開日2021-05-12
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies.
Plos Biol., 19, 2021
7MJN
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BU of 7mjn by Molmil
Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to human ACE2 ectodomain (focused refinement of RBD and ACE2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, Spike glycoprotein
著者Zhu, X, Mannar, D, Srivastava, S.S, Berezuk, A.M, Demers, J.P, Saville, J.W, Leopold, K, Li, W, Dimitrov, D.S, Tuttle, K.S, Zhou, S, Chittori, S, Subramaniam, S.
登録日2021-04-20
公開日2021-05-12
最終更新日2024-10-23
実験手法ELECTRON MICROSCOPY (3.29 Å)
主引用文献Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies.
Plos Biol., 19, 2021
7MJG
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BU of 7mjg by Molmil
Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein
著者Zhu, X, Mannar, D, Srivastava, S.S, Berezuk, A.M, Demers, J.P, Saville, J.W, Leopold, K, Li, W, Dimitrov, D.S, Tuttle, K.S, Zhou, S, Chittori, S, Subramaniam, S.
登録日2021-04-20
公開日2021-05-12
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies.
Plos Biol., 19, 2021
7MJM
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BU of 7mjm by Molmil
Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to human ACE2 ectodomain
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Processed angiotensin-converting enzyme 2, ...
著者Zhu, X, Mannar, D, Srivastava, S.S, Berezuk, A.M, Demers, J.P, Saville, J.W, Leopold, K, Li, W, Dimitrov, D.S, Tuttle, K.S, Zhou, S, Chittori, S, Subramaniam, S.
登録日2021-04-20
公開日2021-05-12
最終更新日2024-10-16
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies.
Plos Biol., 19, 2021
7MJK
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BU of 7mjk by Molmil
Cryo-EM structure of the SARS-CoV-2 N501Y mutant spike protein ectodomain bound to Fab ab1 (class 2)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab ab1 Heavy Chain, ...
著者Zhu, X, Mannar, D, Srivastava, S.S, Berezuk, A.M, Demers, J.P, Saville, J.W, Leopold, K, Li, W, Dimitrov, D.S, Tuttle, K.S, Zhou, S, Chittori, S, Subramaniam, S.
登録日2021-04-20
公開日2021-05-12
最終更新日2024-11-13
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Cryo-electron microscopy structures of the N501Y SARS-CoV-2 spike protein in complex with ACE2 and 2 potent neutralizing antibodies.
Plos Biol., 19, 2021
7MEQ
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BU of 7meq by Molmil
Crystal structure of human TMPRSS2 in complex with Nafamostat
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, Transmembrane protease serine 2, ...
著者Fraser, B, Beldar, S, Hutchinson, A, Li, Y, Seitova, A, Edwards, A.M, Benard, F, Arrowsmith, C.H, Halabelian, L, Structural Genomics Consortium (SGC)
登録日2021-04-07
公開日2021-04-21
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure and activity of human TMPRSS2 protease implicated in SARS-CoV-2 activation.
Nat.Chem.Biol., 18, 2022
8G47
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BU of 8g47 by Molmil
KRAS G12C complex with GDP and AMG 510 imaged on a cryo-EM imaging scaffold
分子名称: AMG 510 (bound form), GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ...
著者Castells-Graells, R, Sawaya, M.R, Yeates, T.O.
登録日2023-02-08
公開日2023-08-09
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.19 Å)
主引用文献Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G3K
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BU of 8g3k by Molmil
Cryo-EM imaging scaffold subunits A and B used to display KRAS G12C complex with GDP
分子名称: Cob_adeno_trans domain-containing protein, Cryo-EM imaging scaffold subunit B with DARPin - RCG-33
著者Castells-Graells, R, Sawaya, M.R, Yeates, T.O.
登録日2023-02-08
公開日2023-08-09
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G4E
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BU of 8g4e by Molmil
Green Fluorescence Protein imaged on a cryo-EM imaging scaffold
分子名称: RCG-10 - Cryo-EM imaging scaffold subunit B fused to DARPin, Superfolder Green Fluorescent Protein
著者Castells-Graells, R, Sawaya, M.R, Yeates, T.O.
登録日2023-02-09
公開日2023-08-09
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G4H
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BU of 8g4h by Molmil
KRAS G13C complex with GDP imaged on a cryo-EM imaging scaffold
分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Castells-Graells, R, Sawaya, M.R, Yeates, T.O.
登録日2023-02-09
公開日2023-08-09
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (2.87 Å)
主引用文献Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G42
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BU of 8g42 by Molmil
KRAS G12C complex with GDP imaged on a cryo-EM imaging scaffold
分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Castells-Graells, R, Sawaya, M.R, Yeates, T.O.
登録日2023-02-08
公開日2023-08-09
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold.
Proc.Natl.Acad.Sci.USA, 120, 2023
8G4F
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BU of 8g4f by Molmil
KRAS G12V complex with GDP imaged on a cryo-EM imaging scaffold
分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Castells-Graells, R, Sawaya, M.R, Yeates, T.O.
登録日2023-02-09
公開日2023-08-09
最終更新日2023-09-27
実験手法ELECTRON MICROSCOPY (2.91 Å)
主引用文献Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold.
Proc.Natl.Acad.Sci.USA, 120, 2023

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件を2025-01-29に公開中

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