1ULH
 
 | | A short peptide insertion crucial for angiostatic activity of human tryptophanyl-tRNA synthetase | | 分子名称: | Tryptophanyl-tRNA synthetase | | 著者 | Kise, Y, Sengoku, T, Ishii, R, Yokoyama, S, Park, S.G, Lee, S.W, Kim, S, Nureki, O, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2003-09-12 | | 公開日 | 2004-02-03 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | A short peptide insertion crucial for angiostatic activity of human tryptophanyl-tRNA synthetase
Nat.Struct.Mol.Biol., 11, 2004
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6IEY
 | | Crystal structure of Chloramphenicol-Metabolizaing Enzyme EstDL136-Chloramphenicol complex | | 分子名称: | CHLORAMPHENICOL, Esterase | | 著者 | Kim, S.H, Kang, P.A, Han, K.T, Lee, S.W, Rhee, S.K. | | 登録日 | 2018-09-18 | | 公開日 | 2019-02-06 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.097 Å) | | 主引用文献 | Crystal structure of chloramphenicol-metabolizing enzyme EstDL136 from a metagenome.
PLoS ONE, 14, 2019
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6AAE
 | | Crystal structure of Chloramphenicol-Metabolizaing Enzyme EstDL136 | | 分子名称: | DI(HYDROXYETHYL)ETHER, Esterase, PENTAETHYLENE GLYCOL | | 著者 | Kim, S.H, Kang, P.A, Han, K.T, Lee, S.W, Rhee, S.K. | | 登録日 | 2018-07-18 | | 公開日 | 2019-02-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.641 Å) | | 主引用文献 | Crystal structure of chloramphenicol-metabolizing enzyme EstDL136 from a metagenome.
PLoS ONE, 14, 2019
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5GPG
 | | Co-crystal structure of the FK506 binding domain of human FKBP25, Rapamycin and the FRB domain of human mTOR | | 分子名称: | Peptidyl-prolyl cis-trans isomerase FKBP3, RAPAMYCIN IMMUNOSUPPRESSANT DRUG, Serine/threonine-protein kinase mTOR | | 著者 | Lee, H.B, Lee, S.Y, Rhee, H.W, Lee, C.W. | | 登録日 | 2016-08-02 | | 公開日 | 2016-10-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Proximity-Directed Labeling Reveals a New Rapamycin-Induced Heterodimer of FKBP25 and FRB in Live Cells
Acs Cent.Sci., 2, 2016
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5YSO
 | | Crystal structure of Estrogen Related Receptor-3 (ERR-gamma) ligand binding domain with DN200434 | | 分子名称: | 4-[5-oxidanyl-2-phenyl-1-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pent-1-enyl]phenol, Estrogen-related receptor gamma | | 著者 | Cho, S.J, Chin, J.W, Yoon, H.S, Jeon, Y.H, Bae, J.H, Song, J.Y. | | 登録日 | 2017-11-14 | | 公開日 | 2018-12-26 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | | 主引用文献 | A Novel Orally Active Inverse Agonist of Estrogen-related Receptor Gamma (ERR gamma ), DN200434, A Booster of NIS in Anaplastic Thyroid Cancer.
Clin.Cancer Res., 25, 2019
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6A6K
 | | Crystal structure of Estrogen-related Receptor-3 (ERR-gamma) ligand binding domain with DN201000 | | 分子名称: | 3-[(~{E})-5-oxidanyl-2-phenyl-1-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]pent-1-enyl]phenol, Estrogen-related receptor gamma | | 著者 | Yoon, H, Kim, J, Chin, J, Cho, S.J, Song, J. | | 登録日 | 2018-06-28 | | 公開日 | 2019-04-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Discovery of Potent, Selective, and Orally Bioavailable Estrogen-Related Receptor-gamma Inverse Agonists To Restore the Sodium Iodide Symporter Function in Anaplastic Thyroid Cancer.
J. Med. Chem., 62, 2019
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6KNR
 | | Crystal structure of Estrogen-related receptor gamma ligand-binding domain with DN200699 | | 分子名称: | (E)-4-(1-(4-(1-cyclopropylpiperidin-4-yl)phenyl)-5-hydroxy-2-phenylpent-1-en-1-yl)phenol, Estrogen-related receptor gamma | | 著者 | Yoon, H, Kim, J, Chin, J, Song, J, Cho, S.J. | | 登録日 | 2019-08-07 | | 公開日 | 2020-08-12 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.804 Å) | | 主引用文献 | An orally available inverse agonist of estrogen-related receptor gamma showed expanded efficacy for the radioiodine therapy of poorly differentiated thyroid cancer.
Eur.J.Med.Chem., 205, 2020
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6O8R
 | | Syn-safencin 24 | | 分子名称: | Circular bacteriocin, circularin A/uberolysin family | | 著者 | Fields, F.R, Lee, S.W. | | 登録日 | 2019-03-11 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Synthetic Antimicrobial Peptide Tuning Permits Membrane Disruption and Interpeptide Synergy.
Acs Pharmacol Transl Sci, 3, 2020
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6O8J
 | | Syn-safencin | | 分子名称: | Circular bacteriocin, circularin A/uberolysin family | | 著者 | Fields, F.R, Lee, S.W. | | 登録日 | 2019-03-11 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Synthetic Antimicrobial Peptide Tuning Permits Membrane Disruption and Interpeptide Synergy.
Acs Pharmacol Transl Sci, 3, 2020
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6O8P
 | | Syn-safencin 8 | | 分子名称: | Circular bacteriocin, circularin A/uberolysin family | | 著者 | Fields, F.R, Lee, S.W. | | 登録日 | 2019-03-11 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Synthetic Antimicrobial Peptide Tuning Permits Membrane Disruption and Interpeptide Synergy.
Acs Pharmacol Transl Sci, 3, 2020
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6OKX
 | | Solution structure of VEK50RH1/AA | | 分子名称: | Plasminogen-binding group A streptococcal M-like protein PAM | | 著者 | Yuan, Y, Castellino, F.J. | | 登録日 | 2019-04-15 | | 公開日 | 2020-02-26 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes.
J.Struct.Biol., 208, 2019
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6OQJ
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6OKW
 | | Solution structure of VEK50 | | 分子名称: | Plasminogen-binding group A streptococcal M-like protein PAM | | 著者 | Yuan, Y, Castellino, F.J. | | 登録日 | 2019-04-15 | | 公開日 | 2020-02-26 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structural model of the complex of the binding regions of human plasminogen with its M-protein receptor from Streptococcus pyogenes.
J.Struct.Biol., 208, 2019
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6OQ9
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6OQK
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6OKY
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6O8S
 | | Syn-safencin 56 | | 分子名称: | Circular bacteriocin, circularin A/uberolysin family | | 著者 | Fields, F.R, Lee, S.W. | | 登録日 | 2019-03-11 | | 公開日 | 2020-05-13 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Synthetic Antimicrobial Peptide Tuning Permits Membrane Disruption and Interpeptide Synergy.
Acs Pharmacol Transl Sci, 3, 2020
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6O8T
 | | Syn-safencin 96 | | 分子名称: | Circular bacteriocin, circularin A/uberolysin family | | 著者 | Fields, F.R, Lee, S.W. | | 登録日 | 2019-03-11 | | 公開日 | 2020-04-15 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Synthetic Antimicrobial Peptide Tuning Permits Membrane Disruption and Interpeptide Synergy.
Acs Pharmacol Transl Sci, 3, 2020
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6BZJ
 | | Solution structure of AGL55 | | 分子名称: | M protein | | 著者 | Qiu, C, Yuan, Y, Castellino, F.J. | | 登録日 | 2017-12-24 | | 公開日 | 2019-01-16 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Contributions of different modules of the plasminogen-binding Streptococcus pyogenes M-protein that mediate its functional dimerization.
J.Struct.Biol., 204, 2018
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6BZK
 | | Solution structure of KTI55 | | 分子名称: | M protein | | 著者 | Castellino, F.J, Qiu, C, Yuan, Y. | | 登録日 | 2017-12-24 | | 公開日 | 2019-01-16 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Contributions of different modules of the plasminogen-binding Streptococcus pyogenes M-protein that mediate its functional dimerization.
J.Struct.Biol., 204, 2018
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6BZL
 | | Solution structure of VEK75 | | 分子名称: | M protein | | 著者 | Qiu, C, Yuan, Y, Castellino, F.J. | | 登録日 | 2017-12-24 | | 公開日 | 2019-01-16 | | 最終更新日 | 2024-05-01 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Contributions of different modules of the plasminogen-binding Streptococcus pyogenes M-protein that mediate its functional dimerization.
J.Struct.Biol., 204, 2018
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5V4U
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4CKR
 | | Crystal structure of the human DDR1 kinase domain in complex with DDR1-IN-1 | | 分子名称: | 1,2-ETHANEDIOL, 4-[(4-ethylpiperazin-1-yl)methyl]-n-{4-methyl-3-[(2-oxo-2,3-dihydro-1h-indol-5-yl)oxy]phenyl}-3-(trifluoromethyl)benzamide, EPITHELIAL DISCOIDIN DOMAIN-CONTAINING RECEPTOR 1 | | 著者 | Canning, P, Elkins, J.M, Goubin, S, Mahajan, P, Krojer, T, Newman, J.A, Dixon-Clarke, S, Chaikuad, A, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Bullock, A. | | 登録日 | 2014-01-07 | | 公開日 | 2014-01-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Discovery of a Potent and Selective Ddr1 Receptor Tyrosine Kinase Inhibitor.
Acs Chem.Biol., 8, 2013
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3PJ1
 | | Crystal structure of BTK kinase domain complexed with 3-(2,6-Dichloro-phenyl)-7-[4-(2-diethylamino-ethoxy)-phenylamino]-1-methyl-3,4-dihydro-1H-pyrimido[4,5-d]pyrimidin-2-one | | 分子名称: | 3-(2,6-dichlorophenyl)-7-({4-[2-(diethylamino)ethoxy]phenyl}amino)-1-methyl-3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one, Tyrosine-protein kinase BTK | | 著者 | Kuglstatter, A, Wong, A. | | 登録日 | 2010-11-08 | | 公開日 | 2011-01-12 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Insights into the conformational flexibility of Bruton's tyrosine kinase from multiple ligand complex structures.
Protein Sci., 20, 2011
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3PIZ
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