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8R3T
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BU of 8r3t by Molmil
Cofactor-free Tau 4R2N isoform
分子名称: Microtubule-associated protein tau
著者Limorenko, G, Tatli, M, Kolla, R, Nazarov, S, Weil, M.T, Schondorf, D.C, Geist, D, Reinhardt, P, Ehrnhoefer, D.E, Stahlberg, H, Gasparini, L, Lashuel, H.A.
登録日2023-11-10
公開日2023-12-06
最終更新日2024-01-24
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Fully co-factor-free ClearTau platform produces seeding-competent Tau fibrils for reconstructing pathological Tau aggregates.
Nat Commun, 14, 2023
7Q3U
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BU of 7q3u by Molmil
Cryo-EM structure of TDP43 core peptide amyloid fiber
分子名称: TAR DNA-binding protein 43
著者Nazarov, S.
登録日2021-10-28
公開日2023-03-22
最終更新日2023-10-04
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Seeding the aggregation of TDP-43 requires post-fibrillization proteolytic cleavage.
Nat.Neurosci., 26, 2023
8GF7
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BU of 8gf7 by Molmil
Cryo-EM structure of serine 87 O-GlcNAc-modified alpha-synuclein fibrils
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-synuclein
著者Balana, J.A, Nguyen, A.B, Saelices, L, Pratt, R.M.
登録日2023-03-07
公開日2023-11-08
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (4.8 Å)
主引用文献O-GlcNAc forces an alpha-synuclein amyloid strain with notably diminished seeding and pathology.
Nat.Chem.Biol., 20, 2024
1BM7
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BU of 1bm7 by Molmil
HUMAN TRANSTHYRETIN (PREALBUMIN) COMPLEX WITH FLUFENAMIC ACID (2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID)
分子名称: 2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID, PROTEIN (TRANSTHYRETIN)
著者Klabunde, T, Kelly, J.W, Sacchettini, J.C.
登録日1998-07-29
公開日1998-08-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Inhibiting transthyretin conformational changes that lead to amyloid fibril formation.
Proc.Natl.Acad.Sci.USA, 95, 1998
1BMZ
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BU of 1bmz by Molmil
HUMAN TRANSTHYRETIN (PREALBUMIN)
分子名称: PROTEIN (TRANSTHYRETIN)
著者Klabunde, T, Kelly, J.W, Sacchettini, J.C.
登録日1998-07-27
公開日1998-08-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Inhibiting transthyretin conformational changes that lead to amyloid fibril formation.
Proc.Natl.Acad.Sci.USA, 95, 1998

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件を2024-08-14に公開中

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