5H02
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![BU of 5h02 by Molmil](/molmil-images/mine/5h02) | Crystal structure of Methanohalophilus portucalensis glycine sarcosine N-methyltransferase tetramutant (H21G, E23T, E24N, L28S) | 分子名称: | Glycine sarcosine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, TRIMETHYL GLYCINE | 著者 | Lee, Y.R, Lin, T.S, Lai, S.J, Liu, M.S, Lai, M.C, Chan, N.L. | 登録日 | 2016-10-02 | 公開日 | 2016-11-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.776 Å) | 主引用文献 | Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity. Sci Rep, 6, 2016
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5GWX
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![BU of 5gwx by Molmil](/molmil-images/mine/5gwx) | Crystal structure of glycine sarcosine N-methyltransferase from Methanohalophilus portucalensis in complex with S-adenosylmethionine and sarcosine | 分子名称: | 1,2-ETHANEDIOL, Glycine sarcosine N-methyltransferase, S-ADENOSYLMETHIONINE, ... | 著者 | Lee, Y.R, Lin, T.S, Lai, S.J, Liu, M.S, Lai, M.C, Chan, N.L. | 登録日 | 2016-09-14 | 公開日 | 2016-11-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.205 Å) | 主引用文献 | Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity. Sci Rep, 6, 2016
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5HIL
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![BU of 5hil by Molmil](/molmil-images/mine/5hil) | Crystal structure of glycine sarcosine N-methyltransferase from Methanohalophilus portucalensis in complex with S-adenosylhomocysteine and sarcosine | 分子名称: | 1,2-ETHANEDIOL, Glycine sarcosine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Lee, Y.R, Lin, T.S, Lai, S.J, Liu, M.S, Lai, M.C, Chan, N.L. | 登録日 | 2016-01-12 | 公開日 | 2016-11-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.471 Å) | 主引用文献 | Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity Sci Rep, 6, 2016
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5HIK
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![BU of 5hik by Molmil](/molmil-images/mine/5hik) | Crystal structure of glycine sarcosine N-methyltransferase from Methanohalophilus portucalensis in complex with S-adenosylmethionine | 分子名称: | 1,2-ETHANEDIOL, Glycine sarcosine N-methyltransferase, S-ADENOSYLMETHIONINE | 著者 | Lee, Y.R, Lin, T.S, Lai, S.J, Liu, M.S, Lai, M.C, Chan, N.L. | 登録日 | 2016-01-12 | 公開日 | 2016-11-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.354 Å) | 主引用文献 | Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity Sci Rep, 6, 2016
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5HIJ
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![BU of 5hij by Molmil](/molmil-images/mine/5hij) | Crystal structure of glycine sarcosine N-methyltransferase from Methanohalophilus portucalensis in complex with betaine | 分子名称: | Glycine sarcosine N-methyltransferase, TRIMETHYL GLYCINE | 著者 | Lee, Y.R, Lin, T.S, Lai, S.J, Liu, M.S, Lai, M.C, Chan, N.L. | 登録日 | 2016-01-12 | 公開日 | 2016-11-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity Sci Rep, 6, 2016
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5HII
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![BU of 5hii by Molmil](/molmil-images/mine/5hii) | Crystal structure of glycine sarcosine N-methyltransferase (GSMT) from Methanohalophilus portucalensis (apo form) | 分子名称: | 1,2-ETHANEDIOL, Glycine sarcosine N-methyltransferase | 著者 | Lee, Y.R, Lin, T.S, Lai, S.J, Liu, M.S, Lai, M.C, Chan, N.L. | 登録日 | 2016-01-12 | 公開日 | 2016-11-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity Sci Rep, 6, 2016
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5HIM
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![BU of 5him by Molmil](/molmil-images/mine/5him) | Crystal structure of glycine sarcosine N-methyltransferase from Methanohalophilus portucalensis in complex with S-adenosylhomocysteine and dimethylglycine | 分子名称: | 1,2-ETHANEDIOL, Glycine sarcosine N-methyltransferase, N,N-DIMETHYLGLYCINE, ... | 著者 | Lee, Y.R, Lin, T.S, Lai, S.J, Liu, M.S, Lai, M.C, Chan, N.L. | 登録日 | 2016-01-12 | 公開日 | 2016-11-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.338 Å) | 主引用文献 | Structural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity Sci Rep, 6, 2016
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4ZHT
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![BU of 4zht by Molmil](/molmil-images/mine/4zht) | Crystal structure of UDP-GlcNAc 2-epimerase | 分子名称: | 2-acetamido-2-deoxy-beta-D-mannopyranose, Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, CYTIDINE-5'-MONOPHOSPHATE-5-N-ACETYLNEURAMINIC ACID, ... | 著者 | Chen, S.C, Yang, C.S, Ko, T.P, Chen, Y. | 登録日 | 2015-04-27 | 公開日 | 2016-06-01 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Mechanism and inhibition of human UDP-GlcNAc 2-epimerase, the key enzyme in sialic acid biosynthesis. Sci Rep, 6, 2016
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4QVG
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![BU of 4qvg by Molmil](/molmil-images/mine/4qvg) | Crystal structure of S-adenosylmethionine-dependent methyltransferase SibL in its apo form | 分子名称: | SibL | 著者 | Liu, J.S, Chen, S.C, Huang, C.H, Yang, C.S, Chen, Y. | 登録日 | 2014-07-15 | 公開日 | 2015-05-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structure and mechanism of an antibiotics-synthesizing 3-hydroxykynurenine C-methyltransferase Sci Rep, 5, 2015
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5XVS
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![BU of 5xvs by Molmil](/molmil-images/mine/5xvs) | Crystal structure of UDP-GlcNAc 2-epimerase NeuC complexed with UDP | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GDP/UDP-N,N'-diacetylbacillosamine 2-epimerase (Hydrolyzing), LITHIUM ION, ... | 著者 | Ko, T.P, Hsieh, T.J, Chen, S.C, Wu, S.C, Guan, H.H, Yang, C.H, Chen, C.J, Chen, Y. | 登録日 | 2017-06-28 | 公開日 | 2018-04-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.383 Å) | 主引用文献 | The tetrameric structure of sialic acid-synthesizing UDP-GlcNAc 2-epimerase fromAcinetobacter baumannii: A comparative study with human GNE. J. Biol. Chem., 293, 2018
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5ZLR
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![BU of 5zlr by Molmil](/molmil-images/mine/5zlr) | Structure of NeuC | 分子名称: | GDP/UDP-N,N'-diacetylbacillosamine 2-epimerase (Hydrolyzing), LITHIUM ION, SULFATE ION | 著者 | Ko, T.P, Hsieh, T.J, Yang, C.S, Chen, Y. | 登録日 | 2018-03-29 | 公開日 | 2018-05-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | The tetrameric structure of sialic acid-synthesizing UDP-GlcNAc 2-epimerase fromAcinetobacter baumannii: A comparative study with human GNE. J. Biol. Chem., 293, 2018
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5ZLT
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![BU of 5zlt by Molmil](/molmil-images/mine/5zlt) | Crystal structure of UDP-GlcNAc 2-epimerase NeuC complexed with UDP | 分子名称: | GDP/UDP-N,N'-diacetylbacillosamine 2-epimerase (Hydrolyzing), SULFATE ION, URIDINE-5'-DIPHOSPHATE | 著者 | Ko, T.P, Hsieh, T.J, Yang, C.S, Chen, Y. | 登録日 | 2018-03-29 | 公開日 | 2018-05-16 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The tetrameric structure of sialic acid-synthesizing UDP-GlcNAc 2-epimerase fromAcinetobacter baumannii: A comparative study with human GNE. J. Biol. Chem., 293, 2018
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5BND
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![BU of 5bnd by Molmil](/molmil-images/mine/5bnd) | |
7XJW
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![BU of 7xjw by Molmil](/molmil-images/mine/7xjw) | Crystal structure of canine coronavirus main protease in complex with GC376 | 分子名称: | (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, ORF1a polyprotein | 著者 | Wang, Y.C, Yang, C.S, Hou, M.H, Tsai, C.L, Chiu, Y.F, Chen, Y. | 登録日 | 2022-04-18 | 公開日 | 2023-05-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | A Structural Comparison of SARS-CoV-2 Main Protease and Animal Coronaviral Main Protease Reveals Species-Specific Ligand Binding and Dimerization Mechanism. Int J Mol Sci, 23, 2022
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7YA2
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![BU of 7ya2 by Molmil](/molmil-images/mine/7ya2) | |
6ACS
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![BU of 6acs by Molmil](/molmil-images/mine/6acs) | poly-cis-prenyltransferase | 分子名称: | CITRIC ACID, Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), GLYCEROL, ... | 著者 | Ko, T.-P, Chen, Y. | 登録日 | 2018-07-27 | 公開日 | 2018-12-19 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Structure of undecaprenyl pyrophosphate synthase from Acinetobacter baumannii Acta Crystallogr F Struct Biol Commun, 74, 2018
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3THB
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![BU of 3thb by Molmil](/molmil-images/mine/3thb) | Structure of PLK1 kinase domain in complex with a benzolactam-derived inhibitor | 分子名称: | 9-chloro-2-({5-[3-(dimethylamino)propyl]-2-methylpyridin-3-yl}amino)-5,7-dihydro-6H-pyrimido[5,4-d][1]benzazepine-6-thi one, Serine/threonine-protein kinase PLK1, ZINC ION | 著者 | Sintchak, M.D. | 登録日 | 2011-08-18 | 公開日 | 2011-11-23 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Discovery of a Potent and Orally Bioavailable Benzolactam-Derived Inhibitor of Polo-Like Kinase 1 (MLN0905). J.Med.Chem., 55, 2012
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