2HXM
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![BU of 2hxm by Molmil](/molmil-images/mine/2hxm) | Complex of UNG2 and a small Molecule synthetic Inhibitor | 分子名称: | 4-[(1E,7E)-8-(2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL)-3,6-DIOXA-2,7-DIAZAOCTA-1,7-DIEN-1-YL]BENZOIC ACID, Uracil-DNA glycosylase | 著者 | Bianchet, M.A, Krosky, D.J, Ghung, S, Seiple, L, Amzel, L.M, Stivers, J.T. | 登録日 | 2006-08-03 | 公開日 | 2006-12-05 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Mimicking damaged DNA with a small molecule inhibitor of human UNG2. Nucleic Acids Res., 34, 2006
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1LMZ
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2OXM
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![BU of 2oxm by Molmil](/molmil-images/mine/2oxm) | Crystal structure of a UNG2/modified DNA complex that represent a stabilized short-lived extrahelical state in ezymatic DNA base flipping | 分子名称: | DNA (5'-D(*AP*AP*AP*GP*AP*TP*(4MF)P*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*TP*AP*TP*CP*TP*T)-3'), Uracil-DNA glycosylase | 著者 | Bianchet, M.A, Krosky, D.J, Stivers, J.T, Amzel, L.M. | 登録日 | 2007-02-20 | 公開日 | 2007-10-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Enzymatic capture of an extrahelical thymine in the search for uracil in DNA. Nature, 449, 2007
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2OYT
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![BU of 2oyt by Molmil](/molmil-images/mine/2oyt) | Crystal Structure of UNG2/DNA(TM) | 分子名称: | DNA strand1, DNA strand2, Uracil-DNA glycosylase | 著者 | Bianchet, M.A, Krosky, D.J, Stivers, J.T, Amzel, L.M. | 登録日 | 2007-02-22 | 公開日 | 2007-10-30 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Enzymatic capture of an extrahelical thymine in the search for uracil in DNA. Nature, 449, 2007
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3FCI
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![BU of 3fci by Molmil](/molmil-images/mine/3fci) | Complex of UNG2 and a fragment-based designed inhibitor | 分子名称: | 3-{(E)-[(3-{[(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)methyl]amino}propoxy)imino]methyl}benzoic acid, SODIUM ION, THIOCYANATE ION, ... | 著者 | Bianchet, M.A, Chung, S, Parker, J.B, Amzel, L.M, Stivers, J.T. | 登録日 | 2008-11-21 | 公開日 | 2009-04-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | 主引用文献 | Impact of linker strain and flexibility in the design of a fragment-based inhibitor Nat.Chem.Biol., 5, 2009
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3FCF
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![BU of 3fcf by Molmil](/molmil-images/mine/3fcf) | Complex of UNG2 and a fragment-based designed inhibitor | 分子名称: | 3-[(1E,7E)-8-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)-3,6-dioxa-2,7-diazaocta-1,7-dien-1-yl]benzoic acid, THIOCYANATE ION, Uracil-DNA glycosylase | 著者 | Bianchet, M.A, Chung, S, Parker, J.B, Amzel, L.M, Stivers, J.T. | 登録日 | 2008-11-21 | 公開日 | 2009-04-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | 主引用文献 | Impact of linker strain and flexibility in the design of a fragment-based inhibitor Nat.Chem.Biol., 5, 2009
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3FCL
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![BU of 3fcl by Molmil](/molmil-images/mine/3fcl) | Complex of UNG2 and a fragment-based designed inhibitor | 分子名称: | 3-{[(4-{[(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)methyl]amino}butyl)amino]methyl}benzoic acid, THIOCYANATE ION, Uracil-DNA glycosylase | 著者 | Bianchet, M.A, Chung, S, Parker, J.B, Amzel, L.M, Stivers, J.T. | 登録日 | 2008-11-21 | 公開日 | 2009-04-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Impact of linker strain and flexibility in the design of a fragment-based inhibitor Nat.Chem.Biol., 5, 2009
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3FCK
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![BU of 3fck by Molmil](/molmil-images/mine/3fck) | Complex of UNG2 and a fragment-based design inhibitor | 分子名称: | 3-({[3-({[(1E)-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)methylidene]amino}oxy)propyl]amino}methyl)benzoic acid, Uracil-DNA glycosylase | 著者 | Bianchet, M.A, Chung, S, Parker, J.B, Amzel, L.M, Stivers, J.T. | 登録日 | 2008-11-21 | 公開日 | 2009-04-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Impact of linker strain and flexibility in the design of a fragment-based inhibitor Nat.Chem.Biol., 5, 2009
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