8UDS
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7UUR
| The 1.67 Angstrom CryoEM structure of the [NiFe]-hydrogenase Huc from Mycobacterium smegmatis - catalytic dimer (Huc2S2L) | 分子名称: | CARBONMONOXIDE-(DICYANO) IRON, FE3-S4 CLUSTER, HYDROXIDE ION, ... | 著者 | Grinter, R, Venugopal, H, Kropp, A, Greening, C. | 登録日 | 2022-04-28 | 公開日 | 2023-01-04 | 最終更新日 | 2024-11-06 | 実験手法 | ELECTRON MICROSCOPY (1.67 Å) | 主引用文献 | Structural basis for bacterial energy extraction from atmospheric hydrogen. Nature, 615, 2023
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7UUS
| The CryoEM structure of the [NiFe]-hydrogenase Huc from Mycobacterium smegmatis - Full complex focused refinement of stalk | 分子名称: | CARBONMONOXIDE-(DICYANO) IRON, FE3-S4 CLUSTER, Hydrogenase-2, ... | 著者 | Grinter, R, Venugopal, H, Kropp, A, Greening, C. | 登録日 | 2022-04-28 | 公開日 | 2023-01-04 | 最終更新日 | 2024-10-16 | 実験手法 | ELECTRON MICROSCOPY (8 Å) | 主引用文献 | Structural basis for bacterial energy extraction from atmospheric hydrogen. Nature, 615, 2023
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7UTD
| The 2.19-angstrom CryoEM structure of the [NiFe]-hydrogenase Huc from Mycobacterium smegmatis - Complex minus stalk | 分子名称: | CARBONMONOXIDE-(DICYANO) IRON, FE3-S4 CLUSTER, Hydrogenase-2, ... | 著者 | Grinter, R, Venugopal, H, Kropp, A, Greening, C. | 登録日 | 2022-04-26 | 公開日 | 2023-01-04 | 最終更新日 | 2024-11-06 | 実験手法 | ELECTRON MICROSCOPY (2.19 Å) | 主引用文献 | Structural basis for bacterial energy extraction from atmospheric hydrogen. Nature, 615, 2023
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8DQV
| The 1.52 angstrom CryoEM structure of the [NiFe]-hydrogenase Huc from Mycobacterium smegmatis - catalytic dimer (Huc2S2L) | 分子名称: | CARBONMONOXIDE-(DICYANO) IRON, FE3-S4 CLUSTER, Hydrogenase-2, ... | 著者 | Grinter, R, Venugopal, H, Kropp, A, Greening, C. | 登録日 | 2022-07-20 | 公開日 | 2023-01-04 | 最終更新日 | 2023-03-29 | 実験手法 | ELECTRON MICROSCOPY (1.52 Å) | 主引用文献 | Structural basis for bacterial energy extraction from atmospheric hydrogen. Nature, 615, 2023
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8OKH
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8SMQ
| Crystal Structure of the N-terminal Domain of the Cryptic Surface Protein (CD630_25440) from Clostridium difficile. | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | 著者 | Minasov, G, Shuvalova, L, Brunzelle, J.S, Kiryukhina, O, Wawrzak, Z, Satchell, K.J.F, Center for Structural Biology of Infectious Diseases (CSBID), Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2023-04-26 | 公開日 | 2023-05-10 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Protein target highlights in CASP15: Analysis of models by structure providers. Proteins, 91, 2023
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6V4V
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5VE6
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8UEM
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5JZJ
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5JZN
| Crystal structure of DCLK1-KD in complex with NVP-TAE684 | 分子名称: | 5-CHLORO-N-[2-METHOXY-4-[4-(4-METHYLPIPERAZIN-1-YL)PIPERIDIN-1-YL]PHENYL]-N'-(2-PROPAN-2-YLSULFONYLPHENYL)PYRIMIDINE-2,4-DIAMINE, SULFATE ION, Serine/threonine-protein kinase DCLK1 | 著者 | Patel, O, Lucet, I. | 登録日 | 2016-05-17 | 公開日 | 2016-08-24 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Biochemical and Structural Insights into Doublecortin-like Kinase Domain 1. Structure, 24, 2016
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7KXW
| Crystal structure of DCLK1-KD in complex with DCLK1-IN-1 | 分子名称: | 2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}-11-methyl-5-(2,2,2-trifluoroethyl)-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one, DI(HYDROXYETHYL)ETHER, Serine/threonine-protein kinase DCLK1, ... | 著者 | Patel, O, Lucet, I. | 登録日 | 2020-12-05 | 公開日 | 2021-09-22 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3.002 Å) | 主引用文献 | Structural basis for small molecule targeting of Doublecortin Like Kinase 1 with DCLK1-IN-1. Commun Biol, 4, 2021
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7KX8
| Crystal structure of DCLK1-Cter in complex with FMF-03-055-1 | 分子名称: | 5-ethyl-2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}-11-methyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one, Serine/threonine-protein kinase DCLK1 | 著者 | Patel, O, Lucet, I. | 登録日 | 2020-12-03 | 公開日 | 2021-09-22 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural basis for small molecule targeting of Doublecortin Like Kinase 1 with DCLK1-IN-1. Commun Biol, 4, 2021
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7KX6
| Crystal structure of DCLK1-KD in complex with XMD8-85 | 分子名称: | 2-{[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}-5,11-dimethyl-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one, Serine/threonine-protein kinase DCLK1 | 著者 | Patel, O, Lucet, I. | 登録日 | 2020-12-03 | 公開日 | 2021-09-22 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for small molecule targeting of Doublecortin Like Kinase 1 with DCLK1-IN-1. Commun Biol, 4, 2021
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8DGN
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8DGM
| 14-3-3 epsilon bound to phosphorylated PEAK1 (pT1165) peptide | 分子名称: | 1,2-ETHANEDIOL, 14-3-3 protein epsilon, Inactive tyrosine-protein kinase PEAK1 | 著者 | Roy, M.J, Hardy, J.M, Lucet, I.S. | 登録日 | 2022-06-24 | 公開日 | 2023-06-07 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling. Nat Commun, 14, 2023
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8DGO
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8DGP
| 14-3-3 epsilon bound to phosphorylated PEAK3 (pS69) peptide | 分子名称: | 1,2-ETHANEDIOL, 14-3-3 protein epsilon, Phosphorylated PEAK3 (pS69) peptide, ... | 著者 | Roy, M.J, Hardy, J.M, Lucet, I.S. | 登録日 | 2022-06-24 | 公開日 | 2023-06-07 | 最終更新日 | 2024-10-23 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural mapping of PEAK pseudokinase interactions identifies 14-3-3 as a molecular switch for PEAK3 signaling. Nat Commun, 14, 2023
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