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1NTP
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BU of 1ntp by Molmil
USE OF THE NEUTRON DIFFRACTION H/D EXCHANGE TECHNIQUE TO DETERMINE THE CONFORMATIONAL DYNAMICS OF TRYPSIN
分子名称: BETA-TRYPSIN, PHOSPHORYLISOPROPANE
著者Kossiakoff, A.A.
登録日1987-09-16
公開日1988-01-16
最終更新日2017-11-29
実験手法NEUTRON DIFFRACTION (1.8 Å)
主引用文献Use of the neutron diffraction--H/D exchange technique to determine the conformational dynamics of trypsin
Basic Life Sci., 27, 1984
1TGN
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BU of 1tgn by Molmil
STRUCTURE OF BOVINE TRYPSINOGEN AT 1.9 ANGSTROMS RESOLUTION
分子名称: TRYPSINOGEN
著者Kossiakoff, A.A, Stroud, R.M.
登録日1979-09-19
公開日1979-10-19
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Structure of bovine trypsinogen at 1.9 A resolution.
Biochemistry, 16, 1977
3PGF
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BU of 3pgf by Molmil
Crystal structure of maltose bound MBP with a conformationally specific synthetic antigen binder (sAB)
分子名称: GLYCEROL, IMIDAZOLE, Maltose-binding periplasmic protein, ...
著者Kossiakoff, A.A, Duguid, E.M, Sandstrom, A.
登録日2010-11-01
公開日2011-03-09
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Allosteric control of ligand-binding affinity using engineered conformation-specific effector proteins.
Nat.Struct.Mol.Biol., 18, 2011
1F6F
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BU of 1f6f by Molmil
CRYSTAL STRUCTURE OF THE TERNARY COMPLEX BETWEEN OVINE PLACENTAL LACTOGEN AND THE EXTRACELLULAR DOMAIN OF THE RAT PROLACTIN RECEPTOR
分子名称: PLACENTAL LACTOGEN, PROLACTIN RECEPTOR
著者Elkins, P.A, Christinger, H.W, Sandowski, Y, Sakal, E, Gertler, A, De Vos, A.M, Kossiakoff, A.A.
登録日2000-06-21
公開日2000-07-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Ternary complex between placental lactogen and the extracellular domain of the prolactin receptor.
Nat.Struct.Biol., 7, 2000
3BOI
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BU of 3boi by Molmil
Snow Flea Antifreeze Protein Racemate
分子名称: 6.5 kDa glycine-rich antifreeze protein
著者Pentelute, B.L, Kent, S.B.H, Gates, Z.P, Tereshko, V, Kossiakoff, A.A, Kurutz, J, Dashnau, J, Vaderkooi, J.M.
登録日2007-12-17
公開日2008-09-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献X-ray structure of snow flea antifreeze protein determined by racemic crystallization of synthetic protein enantiomers
J.Am.Chem.Soc., 130, 2008
2FXU
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BU of 2fxu by Molmil
X-ray Structure of Bistramide A- Actin Complex at 1.35 A resolution.
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin, alpha skeletal muscle, ...
著者Rizvi, S.A, Tereshko, V, Kossiakoff, A.A, Kozmin, S.A.
登録日2006-02-06
公開日2006-03-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structure of bistramide a-actin complex at a 1.35 A resolution
J.Am.Chem.Soc., 128, 2006
2R8S
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BU of 2r8s by Molmil
High resolution structure of a specific synthetic FAB bound to P4-P6 RNA ribozyme domain
分子名称: Fab heavy chain, Fab light chain, MAGNESIUM ION, ...
著者Ye, J.D, Tereshko, V, Sidhu, S.S, Koide, S, Kossiakoff, A.A, Piccirilli, J.A.
登録日2007-09-11
公開日2007-12-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Synthetic antibodies for specific recognition and crystallization of structured RNA
Proc.Natl.Acad.Sci.Usa, 105, 2008
7PHQ
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BU of 7phq by Molmil
Structure of homo-dimeric Staphylococcus capitis divalent metal ion transporter (DMT) by NabFab-fiducial assisted cryo-EM
分子名称: Anti-Fab nanobody, DMT-Nb16_4, Divalent metal cation transporter MntH, ...
著者Bloch, J.S, Mukherjee, S, Kowal, J, Kossiakoff, A.A, Locher, K.P.
登録日2021-08-18
公開日2021-09-01
最終更新日2021-12-01
実験手法ELECTRON MICROSCOPY (8.45 Å)
主引用文献Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021
7PIJ
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BU of 7pij by Molmil
Structure of Staphylococcus capitis divalent metal ion transporter (DMT) by NabFab-fiducial assisted cryo-EM
分子名称: Anti-Fab nanobody, DMTNb16_4, Divalent metal cation transporter MntH, ...
著者Bloch, J.S, Mukherjee, S, Kowal, J, Kossiakoff, A.A, Locher, K.P.
登録日2021-08-20
公開日2021-09-01
最終更新日2021-12-01
実験手法ELECTRON MICROSCOPY (3.78 Å)
主引用文献Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021
7PHP
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BU of 7php by Molmil
Structure of Multidrug and Toxin Compound Extrusion (MATE) transporter NorM by NabFab-fiducial assisted cryo-EM
分子名称: Anti-Fab nanobody, Multidrug resistance protein NorM, NabFab HC, ...
著者Bloch, J.S, Mukherjee, S, Kowal, J, Niederer, M, Pardon, E, Steyaert, J, Kossiakoff, A.A, Locher, K.P.
登録日2021-08-18
公開日2021-09-01
最終更新日2021-12-01
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins.
Proc.Natl.Acad.Sci.USA, 118, 2021
3HHR
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BU of 3hhr by Molmil
HUMAN GROWTH HORMONE AND EXTRACELLULAR DOMAIN OF ITS RECEPTOR: CRYSTAL STRUCTURE OF THE COMPLEX
分子名称: HUMAN GROWTH HORMONE, HUMAN GROWTH HORMONE RECEPTOR (hGHbp)
著者De Vos, A.M, Ultsch, M, Kossiakoff, A.A.
登録日1993-12-30
公開日1994-04-30
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Human growth hormone and extracellular domain of its receptor: crystal structure of the complex.
Science, 255, 1992
3BOG
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BU of 3bog by Molmil
Snow Flea Antifreeze Protein Quasi-racemate
分子名称: 6.5 kDa glycine-rich antifreeze protein, UNKNOWN LIGAND
著者Pentelute, B.L, Kent, S.B.H, Gates, Z.P, Tereshko, V, Kossiakoff, A.A, Kurutz, J, Dashnau, J, Vaderkooi, J.M.
登録日2007-12-17
公開日2008-09-23
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献X-ray structure of snow flea antifreeze protein determined by racemic crystallization of synthetic protein enantiomers
J.Am.Chem.Soc., 130, 2008
4XTR
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BU of 4xtr by Molmil
Structure of Get3 bound to the transmembrane domain of Pep12
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATPase GET3, ...
著者Mateja, A, Paduch, M, Chang, H.-Y, Szydlowska, A, Kossiakoff, A.A, Hegde, R.S, Keenan, R.J.
登録日2015-01-23
公開日2015-03-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo.
Science, 347, 2015
4XVU
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BU of 4xvu by Molmil
Structure of Get3 bound to the transmembrane domain of Nyv1
分子名称: ADENOSINE-5'-TRIPHOSPHATE, ATPase GET3, Antibody heavy chain, ...
著者Mateja, A, Paduch, M, Chang, H.-Y, Szydlowska, A, Kossiakoff, A.A, Hegde, R.S, Keenan, R.J.
登録日2015-01-28
公開日2015-03-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo.
Science, 347, 2015
4XH2
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BU of 4xh2 by Molmil
Crystal structure of human paxillin LD4 motif in complex with Fab fragment
分子名称: ACETATE ION, ACETYL GROUP, Fab Heavy Chain, ...
著者Nocula-Lugowska, M, Lugowski, M, Salgia, R, Kossiakoff, A.A.
登録日2015-01-04
公開日2015-07-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin.
J.Mol.Biol., 427, 2015
4XMN
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BU of 4xmn by Molmil
Structure of the yeast coat nucleoporin complex, space group P212121
分子名称: Antibody 87 heavy chain, Antibody 87 light chain, Nucleoporin NUP120, ...
著者Stuwe, T, Correia, A.R, Lin, D.H, Paduch, M, Lu, V.T, Kossiakoff, A.A, Hoelz, A.
登録日2015-01-14
公開日2015-03-25
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (7.6 Å)
主引用文献Nuclear pores. Architecture of the nuclear pore complex coat.
Science, 347, 2015
4XWO
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BU of 4xwo by Molmil
Structure of Get3 bound to the transmembrane domain of Sec22
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATPase GET3, ...
著者Mateja, A, Paduch, M, Chang, H.-Y, Szydlowska, A, Kossiakoff, A.A, Hegde, R.S, Keenan, R.J.
登録日2015-01-29
公開日2015-03-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Protein targeting. Structure of the Get3 targeting factor in complex with its membrane protein cargo.
Science, 347, 2015
4XMM
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BU of 4xmm by Molmil
Structure of the yeast coat nucleoporin complex, space group C2
分子名称: Antibody 57 heavy chain, Antibody 57 light chain, Nucleoporin NUP120, ...
著者Stuwe, T, Correia, A.R, Lin, D.H, Paduch, M, Lu, V.T, Kossiakoff, A.A, Hoelz, A.
登録日2015-01-14
公開日2015-03-25
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (7.384 Å)
主引用文献Nuclear pores. Architecture of the nuclear pore complex coat.
Science, 347, 2015
4XGZ
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BU of 4xgz by Molmil
Crystal structure of human paxillin LD2 motif in complex with Fab fragment
分子名称: 1,2-ETHANEDIOL, FAB HEAVY CHAIN, FAB LIGHT CHAIN, ...
著者Nocula-Lugowska, M, Lugowski, M, Salgia, R, Kossiakoff, A.A.
登録日2015-01-04
公開日2015-07-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Engineering Synthetic Antibody Inhibitors Specific for LD2 or LD4 Motifs of Paxillin.
J.Mol.Biol., 427, 2015
8PHW
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BU of 8phw by Molmil
Human OATP1B1
分子名称: CHOLESTEROL HEMISUCCINATE, Fab18 (heavy chain, variable region), ...
著者Ciuta, A.-D, Nosol, K, Kowal, J, Mukherjee, S, Ramirez, A.S, Stieger, B, Kossiakoff, A.A, Locher, K.P.
登録日2023-06-20
公開日2023-09-27
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure of human drug transporters OATP1B1 and OATP1B3.
Nat Commun, 14, 2023
8PG0
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BU of 8pg0 by Molmil
Human OATP1B3
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, BICARBONATE ION, CHOLESTEROL, ...
著者Ciuta, A.-D, Nosol, K, Kowal, J, Mukherjee, S, Ramirez, A.S, Stieger, B, Kossiakoff, A.A, Locher, K.P.
登録日2023-06-17
公開日2023-09-27
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Structure of human drug transporters OATP1B1 and OATP1B3.
Nat Commun, 14, 2023
1FYH
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BU of 1fyh by Molmil
1:1 COMPLEX BETWEEN AN INTERFERON GAMMA SINGLE-CHAIN VARIANT AND ITS RECEPTOR
分子名称: CHLORIDE ION, Interferon gamma, Interferon gamma receptor 1
著者Randal, M, Kossiakoff, A.A.
登録日2000-09-29
公開日2000-10-11
最終更新日2017-06-21
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献The structure and activity of a monomeric interferon-gamma:alpha-chain receptor signaling complex.
Structure, 9, 2001
7PTI
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BU of 7pti by Molmil
STRUCTURAL EFFECTS INDUCED BY REMOVAL OF A DISULFIDE BRIDGE. THE X-RAY STRUCTURE OF THE C30A(SLASH)C51A MUTANT OF BASIC PANCREATIC TRYPSIN INHIBITOR AT 1.6 ANGSTROMS
分子名称: BOVINE PANCREATIC TRYPSIN INHIBITOR, PHOSPHATE ION
著者Eigenbrot, C, Randal, M, Kossiakoff, A.A.
登録日1990-03-08
公開日1991-04-15
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural effects induced by removal of a disulfide-bridge: the X-ray structure of the C30A/C51A mutant of basic pancreatic trypsin inhibitor at 1.6 A.
Protein Eng., 3, 1990
5BK2
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BU of 5bk2 by Molmil
Crystal structure of maltose binding protein in complex with a peristeric synthetic antibody
分子名称: CHLORIDE ION, GLYCEROL, Maltose-binding periplasmic protein, ...
著者Mukherjee, S, Kossiakoff, A.A.
登録日2017-09-12
公開日2018-01-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins.
J. Biol. Chem., 293, 2018
5BK1
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BU of 5bk1 by Molmil
Crystal structure of maltose binding protein in complex with an endosteric synthetic antibody
分子名称: CHLORIDE ION, GLYCEROL, Maltose binding protein, ...
著者Mukherjee, S, Kossiakoff, A.A.
登録日2017-09-12
公開日2018-01-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Engineered synthetic antibodies as probes to quantify the energetic contributions of ligand binding to conformational changes in proteins.
J. Biol. Chem., 293, 2018

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