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1ES7
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BU of 1es7 by Molmil
COMPLEX BETWEEN BMP-2 AND TWO BMP RECEPTOR IA ECTODOMAINS
分子名称: BONE MORPHOGENETIC PROTEIN RECEPTOR IA, BONE MORPHOGENETIC PROTEIN-2
著者Kirsch, T, Sebald, W, Dreyer, M.K.
登録日2000-04-07
公開日2000-10-07
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of the BMP-2-BRIA ectodomain complex.
Nat.Struct.Biol., 7, 2000
1ROD
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BU of 1rod by Molmil
CHIMERIC PROTEIN OF INTERLEUKIN 8 AND HUMAN MELANOMA GROWTH STIMULATING ACTIVITY PROTEIN, NMR
分子名称: CHIMERIC PROTEIN OF INTERLEUKIN 8 AND HUMAN MELANOMA GROWTH STIMULATING ACTIVITY PROTEIN
著者Roesch, P, Sticht, H, Auer, M, Schmitt, B, Besemer, J, Horcher, M, Kirsch, T, Lindley, I.J.D.
登録日1995-11-24
公開日1996-06-10
最終更新日2024-10-23
実験手法SOLUTION NMR
主引用文献Structure and activity of a chimeric interleukin-8-melanoma-growth-stimulatory-activity protein.
Eur.J.Biochem., 235, 1996
1REU
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BU of 1reu by Molmil
Structure of the bone morphogenetic protein 2 mutant L51P
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, bone morphogenetic protein 2
著者Keller, S, Nickel, J, Zhang, J.-L, Sebald, W, Mueller, T.D.
登録日2003-11-07
公開日2004-05-04
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Molecular recognition of BMP-2 and BMP receptor IA.
Nat.Struct.Mol.Biol., 11, 2004
1REW
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BU of 1rew by Molmil
Structural refinement of the complex of bone morphogenetic protein 2 and its type IA receptor
分子名称: bone morphogenetic protein 2, bone morphogenetic protein receptor type IA
著者Keller, S, Nickel, J, Zhang, J.-L, Sebald, W, Mueller, T.D.
登録日2003-11-07
公開日2004-05-04
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.863 Å)
主引用文献Molecular recognition of BMP-2 and BMP receptor IA.
Nat.Struct.Mol.Biol., 11, 2004
6TFV
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BU of 6tfv by Molmil
Crystal Structure of EGFR T790M/V948R in Complex with Covalent Pyrrolopyrimidine 18b
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Epidermal growth factor receptor, ...
著者Niggenaber, J, Mueller, M.P, Rauh, D.
登録日2019-11-14
公開日2020-09-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach.
J.Med.Chem., 63, 2020
6TG1
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BU of 6tg1 by Molmil
Crystal Structure of EGFR T790M/V948R in Complex with Covalent Pyrrolopyrimidine 21b
分子名称: 1,2-ETHANEDIOL, Epidermal growth factor receptor, SODIUM ION, ...
著者Niggenaber, J, Mueller, M.P, Rauh, D.
登録日2019-11-14
公開日2020-09-30
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach.
J.Med.Chem., 63, 2020
6TFU
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BU of 6tfu by Molmil
Crystal Structure of EGFR T790M/V948R in Complex with Covalent Pyrrolopyrimidine 14d
分子名称: Epidermal growth factor receptor, SULFATE ION, ~{N}-[3-[4-[[1-(phenylmethyl)indazol-5-yl]amino]-7~{H}-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]propanamide
著者Niggenaber, J, Mueller, M.P, Rauh, D.
登録日2019-11-14
公開日2020-09-30
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach.
J.Med.Chem., 63, 2020
6TG0
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BU of 6tg0 by Molmil
Crystal Structure of EGFR T790M/V948R in Complex with Covalent Pyrrolopyrimidine 21a
分子名称: 1,2-ETHANEDIOL, Epidermal growth factor receptor, SULFATE ION, ...
著者Niggenaber, J, Mueller, M.P, Rauh, D.
登録日2019-11-14
公開日2020-09-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach.
J.Med.Chem., 63, 2020
6TFW
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BU of 6tfw by Molmil
Crystal Structure of EGFR T790M/V948R in Complex with Covalent Pyrrolopyrimidine 18d
分子名称: CHLORIDE ION, Epidermal growth factor receptor, MAGNESIUM ION, ...
著者Niggenaber, J, Mueller, M.P, Rauh, D.
登録日2019-11-14
公開日2020-09-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach.
J.Med.Chem., 63, 2020
6TFY
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BU of 6tfy by Molmil
Crystal Structure of EGFR T790M/V948R in Complex with Covalent Pyrrolopyrimidine 18c
分子名称: Epidermal growth factor receptor, SULFATE ION, ~{N}-[5-[4-[[3-chloranyl-4-(pyridin-2-ylmethoxy)phenyl]amino]-7~{H}-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(3-oxidanylpropoxy)phenyl]propanamide
著者Niggenaber, J, Mueller, M.P, Rauh, D.
登録日2019-11-14
公開日2020-09-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach.
J.Med.Chem., 63, 2020
6TFZ
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BU of 6tfz by Molmil
Crystal Structure of EGFR T790M/V948R in Complex with Covalent Pyrrolopyrimidine 19
分子名称: 1,2-ETHANEDIOL, Epidermal growth factor receptor, SULFATE ION, ...
著者Niggenaber, J, Mueller, M.P, Rauh, D.
登録日2019-11-14
公開日2020-09-30
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Targeting Her2-insYVMA with Covalent Inhibitors-A Focused Compound Screening and Structure-Based Design Approach.
J.Med.Chem., 63, 2020
7NH4
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BU of 7nh4 by Molmil
Co-Crystal Structure of Akt1 in Complex with Covalent-Allosteric Akt Inhibitor 3
分子名称: ACETATE ION, RAC-alpha serine/threonine-protein kinase, ~{N}-[3-[1-[[4-[5-(hydroxymethyl)-3-phenyl-pyridin-2-yl]phenyl]methyl]piperidin-4-yl]-2-oxidanylidene-1~{H}-benzimidazol-5-yl]propanamide
著者Landel, I, Mueller, M.P, Rauh, D.
登録日2021-02-10
公開日2021-09-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Cellular model system to dissect the isoform-selectivity of Akt inhibitors.
Nat Commun, 12, 2021
7NH5
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BU of 7nh5 by Molmil
Co-Crystal Structure of Akt1 in Complex with Covalent-Allosteric Akt Inhibitor 6
分子名称: ACETATE ION, RAC-alpha serine/threonine-protein kinase, ~{N}-methyl-6-[4-[[4-[2-oxidanylidene-6-(propanoylamino)-3~{H}-benzimidazol-1-yl]piperidin-1-yl]methyl]phenyl]-5-phenyl-pyridine-3-carboxamide
著者Landel, I, Mueller, M.P, Rauh, D.
登録日2021-02-10
公開日2021-09-08
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Cellular model system to dissect the isoform-selectivity of Akt inhibitors.
Nat Commun, 12, 2021
7OK3
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BU of 7ok3 by Molmil
Crystal Structure of KRasG13C in Complex with Nucleotide-based Covalent Inhibitor edaGDP
分子名称: Isoform 2B of GTPase KRas, edaGDP
著者Goebel, L, Mueller, M.P, Rauh, D.
登録日2021-05-17
公開日2022-08-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors.
Elife, 12, 2023
7OK4
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Crystal Structure of KRasG13C in Complex with Nucleotide-based covalent Inhibitor bdaGDP
分子名称: Isoform 2B of GTPase KRas, bdaGDP
著者Goebel, L, Mueller, M.P, Rauh, D.
登録日2021-05-17
公開日2022-08-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors.
Elife, 12, 2023

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件を2024-10-30に公開中

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