7OK4
Crystal Structure of KRasG13C in Complex with Nucleotide-based covalent Inhibitor bdaGDP
Summary for 7OK4
Entry DOI | 10.2210/pdb7ok4/pdb |
Descriptor | Isoform 2B of GTPase KRas, bdaGDP (3 entities in total) |
Functional Keywords | gtpase, ras, kras, krasg13c, nucleotide analogues, bdagdp, hydrolase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 20047.29 |
Authors | Goebel, L.,Mueller, M.P.,Rauh, D. (deposition date: 2021-05-17, release date: 2022-08-03, Last modification date: 2024-02-07) |
Primary citation | Goebel, L.,Kirschner, T.,Koska, S.,Rai, A.,Janning, P.,Maffini, S.,Vatheuer, H.,Czodrowski, P.,Goody, R.S.,Muller, M.P.,Rauh, D. Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors. Elife, 12:-, 2023 Cited by PubMed: 36972177DOI: 10.7554/eLife.82184 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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