7OK4
Crystal Structure of KRasG13C in Complex with Nucleotide-based covalent Inhibitor bdaGDP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Isoform 2B of GTPase KRas | polymer | 170 | 19433.9 | 1 | UniProt (P01116-2) Pfam (PF00071) UniProt (by SIFTS) (P01116) | Homo sapiens (Human) | K-Ras 2,Ki-Ras,c-K-ras,c-Ki-ras |
| 2 | B (A) | bdaGDP | non-polymer | 613.4 | 1 | Chemie (VJB) | |||
| 3 | C (A) | water | water | 18.0 | 106 | Chemie (HOH) |
Sequence modifications
A: 1 - 169 (UniProt: P01116-2)
| PDB | External Database | Details |
|---|---|---|
| His 0 | - | expression tag |
| Cys 13 | Gly 13 | engineered mutation |
| Ser 51 | Cys 51 | engineered mutation |
| Leu 80 | Cys 80 | engineered mutation |
| Ser 118 | Cys 118 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19433.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 613.4 | |
| All* | Total formula weight | 20047.3 |
