6FGC
| Crystal structure of Gephyrin E domain in complex with Artesunate | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ... | 著者 | Kasaragod, V.B, Schindelin, H. | 登録日 | 2018-01-10 | 公開日 | 2019-01-16 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Elucidating the Molecular Basis for Inhibitory Neurotransmission Regulation by Artemisinins. Neuron, 101, 2019
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9EQG
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6YK0
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6YJZ
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6YK1
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7PC0
| GABA-A receptor bound by a-Cobratoxin | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-cobratoxin, ... | 著者 | Kasaragod, V.B, Miller, P.S. | 登録日 | 2021-08-03 | 公開日 | 2022-02-09 | 最終更新日 | 2022-03-02 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Mechanisms of inhibition and activation of extrasynaptic alpha beta GABA A receptors. Nature, 602, 2022
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6FGD
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6HSO
| Crystal structure of the ternary complex of GephE-ADP-Glycine receptor derived peptide | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,1'-benzene-1,4-diylbis(1H-pyrrole-2,5-dione), ACETATE ION, ... | 著者 | Kasaragod, V.B, Schindelin, H. | 登録日 | 2018-10-01 | 公開日 | 2019-01-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Elucidating the Molecular Basis for Inhibitory Neurotransmission Regulation by Artemisinins. Neuron, 101, 2019
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6HSN
| Crystal structure of the ternary complex of GephE-ADP-GABA(A) receptor derived peptide | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,1'-[ethane-1,2-diylbis(oxyethane-2,1-diyl)]bis(1H-pyrrole-2,5-dione), ACETATE ION, ... | 著者 | Kasaragod, V.B, Schindelin, H. | 登録日 | 2018-10-01 | 公開日 | 2019-01-16 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Elucidating the Molecular Basis for Inhibitory Neurotransmission Regulation by Artemisinins. Neuron, 101, 2019
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5ERT
| GephE in complex with Mn(2+) - ADP | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Kasaragod, V.B, Schindelin, H. | 登録日 | 2015-11-15 | 公開日 | 2016-05-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural Framework for Metal Incorporation during Molybdenum Cofactor Biosynthesis. Structure, 24, 2016
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5ERU
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5ERQ
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5ERV
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5ERS
| GephE in complex with Mg(2+) - AMP | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ADENOSINE MONOPHOSPHATE, ... | 著者 | Kasaragod, V.B, Schindelin, H. | 登録日 | 2015-11-15 | 公開日 | 2016-05-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural Framework for Metal Incorporation during Molybdenum Cofactor Biosynthesis. Structure, 24, 2016
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5ERR
| GephE in complex with Mg(2+) - ADP | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Kasaragod, V.B, Schindelin, H. | 登録日 | 2015-11-15 | 公開日 | 2016-05-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural Framework for Metal Incorporation during Molybdenum Cofactor Biosynthesis. Structure, 24, 2016
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6I0Q
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7PBD
| a1b3 GABA-A receptor + GABA | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GAMMA-AMINO-BUTANOIC ACID, ... | 著者 | Miller, P.S, Kasaragod, V.B. | 登録日 | 2021-08-02 | 公開日 | 2022-02-09 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (3.04 Å) | 主引用文献 | Mechanisms of inhibition and activation of extrasynaptic alpha beta GABA A receptors. Nature, 602, 2022
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4PD1
| Structure of gephyrin E domain with Glycine-beta receptor peptide | 分子名称: | ACETATE ION, GLYCEROL, Gephyrin, ... | 著者 | Kasaragod, V.B, Maric, H.M, Schindelin, H. | 登録日 | 2014-04-17 | 公開日 | 2014-08-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (1.975 Å) | 主引用文献 | Modulation of gephyrin-glycine receptor affinity by multivalency. Acs Chem.Biol., 9, 2014
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4PD0
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7PBZ
| a1b3 GABA-A receptor + GABA + Zn2+ | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DECANE, ... | 著者 | Miller, P.S, Kasaragod, V.B. | 登録日 | 2021-08-03 | 公開日 | 2022-02-09 | 最終更新日 | 2023-11-15 | 実験手法 | ELECTRON MICROSCOPY (2.79 Å) | 主引用文献 | Mechanisms of inhibition and activation of extrasynaptic alpha beta GABA A receptors. Nature, 602, 2022
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4TK4
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4TK2
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4TK3
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4TK1
| Geph E in complex with a GABA receptor alpha3 subunit derived peptide in space group P21212 | 分子名称: | BETA-MERCAPTOETHANOL, GLYCEROL, Gamma-aminobutyric acid receptor subunit alpha-3, ... | 著者 | Kasaragod, V.B, Maric, H.M, Schindelin, H. | 登録日 | 2014-05-25 | 公開日 | 2014-12-24 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Molecular basis of the alternative recruitment of GABAA versus glycine receptors through gephyrin. Nat Commun, 5, 2014
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4U90
| GephE in complex with PEG crosslinked GABA receptor alpha3 subunit derived dimeric peptide | 分子名称: | 1,1'-[ethane-1,2-diylbis(oxyethane-2,1-diyl)]bis(1H-pyrrole-2,5-dione), 1,4-BUTANEDIOL, Gamma-aminobutyric acid receptor subunit alpha-3, ... | 著者 | Kasaragod, V.B, Maric, H.M, Schindelin, H. | 登録日 | 2014-08-05 | 公開日 | 2014-12-10 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Design and Synthesis of High-Affinity Dimeric Inhibitors Targeting the Interactions between Gephyrin and Inhibitory Neurotransmitter Receptors. Angew.Chem.Int.Ed.Engl., 54, 2015
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