8PM4
| Cryo-EM structure of the Cas12m-crRNA-target DNA complex | 分子名称: | DNA oligoduplex, non-target strand, chain D, ... | 著者 | Sasnauskas, G, Tamulaitiene, G, Karvelis, T, Bigelyte, G, Siksnys, V. | 登録日 | 2023-06-28 | 公開日 | 2024-02-07 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | 主引用文献 | Innate programmable DNA binding by CRISPR-Cas12m effectors enable efficient base editing. Nucleic Acids Res., 52, 2024
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8BF8
| ISDra2 TnpB in complex with reRNA | 分子名称: | Deinococcus radiodurans R1 chromosome 1, RNA-guided DNA endonuclease TnpB | 著者 | Sasnauskas, G, Tamulaitiene, G, Carabias, A, Siksnys, V, Montoya, G, Druteika, G, Silanskas, A, Venclovas, C, Karvelis, T, Kazlauskas, D. | 登録日 | 2022-10-24 | 公開日 | 2023-04-12 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | TnpB structure reveals minimal functional core of Cas12 nuclease family. Nature, 616, 2023
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8EXA
| ISDra2 TnpB in complex with reRNA and cognate DNA, conformation 1 (RuvC domain resolved) | 分子名称: | DNA (43-MER), RNA (150-MER), RNA-guided DNA endonuclease TnpB | 著者 | Sasnauskas, G, Tamulaitiene, G, Carabias, A, Karvelis, T, Druteika, G, Silanskas, A, Montoya, G, Venclovas, C, Kazlauskas, D, Siksnys, V. | 登録日 | 2022-10-25 | 公開日 | 2023-04-05 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | TnpB structure reveals minimal functional core of Cas12 nuclease family. Nature, 616, 2023
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8EX9
| ISDra2 TnpB in complex with reRNA and cognate DNA, conformation 2 (RuvC domain unresolved) | 分子名称: | DNA (43-MER), RNA (150-MER), RNA-guided DNA endonuclease TnpB | 著者 | Sasnauskas, G, Tamulaitiene, G, Carabias, A, Karvelis, T, Druteika, G, Silanskas, A, Montoya, G, Venclovas, C, Kazlauskas, D, Siksnys, V. | 登録日 | 2022-10-25 | 公開日 | 2023-04-05 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.96 Å) | 主引用文献 | TnpB structure reveals minimal functional core of Cas12 nuclease family. Nature, 616, 2023
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8J12
| Cryo-EM structure of the AsCas12f-sgRNA-target DNA ternary complex | 分子名称: | DNA (38-MER), MAGNESIUM ION, RNA (247-MER), ... | 著者 | Hino, T, Omura, N.S, Nakagawa, R, Togashi, T, Takeda, N.S, Hiramoto, T, Tasaka, S, Hirano, H, Tokuyama, T, Uosaki, H, Ishiguro, H, Yamano, H, Ozaki, Y, Motooka, D, Mori, H, Kirita, Y, Kise, Y, Itoh, Y, Matoba, S, Aburatani, H, Yachie, N, Siksnys, V, Ohmori, T, Hoshino, A, Nureki, O. | 登録日 | 2023-04-12 | 公開日 | 2023-09-27 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | An AsCas12f-based compact genome-editing tool derived by deep mutational scanning and structural analysis. Cell, 186, 2023
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8J1J
| Cryo-EM structure of the AsCas12f-YHAM-sgRNAS3-5v7-target DNA | 分子名称: | DNA (38-MER), MAGNESIUM ION, RNA (118-MER), ... | 著者 | Hino, T, Omura, N.S, Nakagawa, R, Togashi, T, Takeda, N.S, Hiramoto, T, Tasaka, S, Hirano, H, Tokuyama, T, Uosaki, H, Ishiguro, H, Yamano, H, Ozaki, Y, Motooka, D, Mori, H, Kirita, Y, Kise, Y, Itoh, Y, Matoba, S, Aburatani, H, Yachie, N, Siksnys, V, Ohmori, T, Hoshino, A, Nureki, O. | 登録日 | 2023-04-13 | 公開日 | 2023-09-27 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (2.91 Å) | 主引用文献 | An AsCas12f-based compact genome-editing tool derived by deep mutational scanning and structural analysis. Cell, 186, 2023
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8J3R
| Cryo-EM structure of the AsCas12f-HKRA-sgRNAS3-5v7-target DNA | 分子名称: | DNA (37-MER), DNA (38-MER), MAGNESIUM ION, ... | 著者 | Hino, T, Omura, N.S, Nakagawa, R, Togashi, T, Takeda, N.S, Hiramoto, T, Tasaka, S, Hirano, H, Tokuyama, T, Uosaki, H, Ishiguro, H, Yamano, H, Ozaki, Y, Motooka, D, Mori, H, Kirita, Y, Kise, Y, Itoh, Y, Matoba, S, Aburatani, H, Yachie, N, Siksnys, V, Ohmori, T, Hoshino, A, Nureki, O. | 登録日 | 2023-04-18 | 公開日 | 2023-09-27 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | An AsCas12f-based compact genome-editing tool derived by deep mutational scanning and structural analysis. Cell, 186, 2023
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