3RHY
 
 | | Crystal structure of the dimethylarginine dimethylaminohydrolase adduct with 4-chloro-2-hydroxymethylpyridine | | 分子名称: | (4-chloropyridin-2-yl)methanol, N(G),N(G)-dimethylarginine dimethylaminohydrolase | | 著者 | Monzingo, A.F, Johnson, C.M, Ke, Z, Yoon, D.-W, Linsky, T.W, Guo, H, Fast, W, Robertus, J.D. | | 登録日 | 2011-04-12 | | 公開日 | 2011-06-15 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | On the mechanism of dimethylarginine dimethylaminohydrolase inactivation by 4-halopyridines.
J.Am.Chem.Soc., 133, 2011
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1W4F
 | | Peripheral-subunit from mesophilic, thermophilic and hyperthermophilic bacteria fold by ultrafast, apparently two-state transitions | | 分子名称: | DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE | | 著者 | Ferguson, N, Sharpe, T.D, Schartau, P.J, Allen, M.D, Johnson, C.M, Fersht, A.R. | | 登録日 | 2004-07-23 | | 公開日 | 2005-07-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Ultra-Fast Barrier-Limited Folding in the Peripheral Subunit-Binding Domain Family.
J.Mol.Biol., 353, 2005
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1W4G
 | | Peripheral-subunit binding domains from mesophilic, thermophilic, and hyperthermophilic bacteria fold by ultrafast, apparently two-state folding transitions | | 分子名称: | DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE | | 著者 | Ferguson, N, Sharpe, T.D, Schartau, P.J, Allen, M.D, Johnson, C.M, Sato, S, Fersht, A.R. | | 登録日 | 2004-07-23 | | 公開日 | 2005-07-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Ultra-Fast Barrier-Limited Folding in the Peripheral Subunit-Binding Domain Family.
J.Mol.Biol., 353, 2005
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1W4J
 | | Peripheral-subunit binding domains from mesophilic, thermophilic, and hyperthermophilic bacteria fold by ultrafast, apparently two-state transitions | | 分子名称: | PYRUVATE DEHYDROGENASE E2 | | 著者 | Ferguson, N, Sharpe, T.D, Schartau, P.J, Allen, M.D, Johnson, C.M, Sato, S, Fersht, A.R. | | 登録日 | 2004-07-23 | | 公開日 | 2005-07-20 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Ultra-fast barrier-limited folding in the peripheral subunit-binding domain family.
J. Mol. Biol., 353, 2005
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5KC1
 | | Structure of the C-terminal dimerization domain of Atg38 | | 分子名称: | 1,2-ETHANEDIOL, AMMONIUM ION, Autophagy-related protein 38, ... | | 著者 | Ohashi, Y, Soler, N, Garcia-Ortegon, M, Zhang, L, Perisic, O, Masson, G.R, Johnson, C.M, Williams, R.J. | | 登録日 | 2016-06-04 | | 公開日 | 2016-10-05 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Characterization of Atg38 and NRBF2, a fifth subunit of the autophagic Vps34/PIK3C3 complex.
Autophagy, 12, 2016
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3ZHF
 | | gamma 2 adaptin EAR domain crystal structure with preS1 site1 peptide NPDWDFN | | 分子名称: | 1,2-ETHANEDIOL, AP-1 COMPLEX SUBUNIT GAMMA-LIKE 2, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Juergens, M.C, Voros, J, Rautureau, G, Shepherd, D, Pye, V.E, Muldoon, J, Johnson, C.M, Ashcroft, A, Freund, S.M.V, Ferguson, N. | | 登録日 | 2012-12-21 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The Hepatitis B Virus Pres1 Domain Hijacks Host Trafficking Proteins by Motif Mimicry.
Nat.Chem.Biol., 9, 2013
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5FVM
 | | Cryo electron microscopy of a complex of Tor and Lst8 | | 分子名称: | SERINE/THREONINE-PROTEIN KINASE TOR2, TARGET OF RAPAMYCIN COMPLEX SUBUNIT LST8 | | 著者 | Baretic, D, Berndt, A, Ohashi, Y, Johnson, C.M, Williams, R.L. | | 登録日 | 2016-02-09 | | 公開日 | 2016-04-20 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (6.7 Å) | | 主引用文献 | Tor Forms a Dimer Through an N-Terminal Helical Solenoid with a Complex Topology
Nat.Commun., 7, 2016
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2YMT
 | | gamma 2 adaptin EAR domain crystal structure with phage peptide GEEWGPWV | | 分子名称: | 1,3-PROPANDIOL, AP-1 COMPLEX SUBUNIT GAMMA-LIKE 2, PHAGE DISPLAY DERIVED GAMMA 2 ADAPTIN EAR DOMAIN BINDING PEPTIDE | | 著者 | Juergens, M.C, Voros, J, Rautureau, G, Shepherd, D, Pye, V.E, Muldoon, J, Johnson, C.M, Ashcroft, A, Freund, S.M.V, Ferguson, N. | | 登録日 | 2012-10-10 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | | 主引用文献 | The Hepatitis B Virus Pres1 Domain Hijacks Host Trafficking Proteins by Motif Mimicry.
Nat.Chem.Biol., 9, 2013
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2Y9U
 | | Structural basis of p63a SAM domain mutants involved in AEC syndrome | | 分子名称: | SULFATE ION, TUMOR PROTEIN 63 | | 著者 | Sathyamurthy, A, Freund, S.M.V, Johnson, C.M, Allen, M.D. | | 登録日 | 2011-02-16 | | 公開日 | 2011-08-03 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural Basis of P63Alpha Sam Domain Mutants Involved in Aec Syndrome.
FEBS J., 278, 2011
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2Y9T
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4BY2
 | | SAS-4 (dCPAP) TCP domain in complex with a Proline Rich Motif of Ana2 (dSTIL) of Drosophila Melanogaster | | 分子名称: | 1,2-ETHANEDIOL, ANASTRAL SPINDLE 2, SAS 4 | | 著者 | Cottee, M.A, Muschalik, N, Wong, Y.L, Johnson, C.M, Johnson, S, Andreeva, A, Oegema, K, Lea, S.M, Raff, J.W, van Breugel, M. | | 登録日 | 2013-07-17 | | 公開日 | 2013-09-18 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | | 主引用文献 | Crystal structures of the CPAP/STIL complex reveal its role in centriole assembly and human microcephaly.
Elife, 2, 2013
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1COA
 | | THE EFFECT OF CAVITY CREATING MUTATIONS IN THE HYDROPHOBIC CORE OF CHYMOTRYPSIN INHIBITOR 2 | | 分子名称: | CHYMOTRYPSIN INHIBITOR 2 | | 著者 | Jackson, S.E, Moracci, M, Elmasry, N, Johnson, C.M, Fersht, A.R. | | 登録日 | 1993-05-14 | | 公開日 | 1994-01-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Effect of cavity-creating mutations in the hydrophobic core of chymotrypsin inhibitor 2.
Biochemistry, 32, 1993
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4BL6
 | | Bicaudal-D uses a parallel, homodimeric coiled coil with heterotypic registry to co-ordinate recruitment of cargos to dynein | | 分子名称: | ARGININE, PROTEIN BICAUDAL D | | 著者 | Liu, Y, Salter, H.K, Holding, A.N, Johnson, C.M, Stephens, E, Lukavsky, P.J, Walshaw, J, Bullock, S.L. | | 登録日 | 2013-05-02 | | 公開日 | 2013-06-12 | | 最終更新日 | 2017-07-12 | | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | | 主引用文献 | Bicaudal-D Uses a Parallel, Homodimeric Coiled Coil with Heterotypic Registry to Coordinate Recruitment of Cargos to Dynein
Genes Dev., 27, 2013
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4BCX
 | | gamma 2 adaptin EAR domain crystal structure | | 分子名称: | 1,3-PROPANDIOL, AP-1 COMPLEX SUBUNIT GAMMA-LIKE 2, IMIDAZOLE | | 著者 | Juergens, M.C, Voros, J, Rautureau, G, Shepherd, D, Pye, V.E, Muldoon, J, Johnson, C.M, Ashcroft, A, Freund, S.M.V, Ferguson, N. | | 登録日 | 2012-10-03 | | 公開日 | 2013-07-10 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Hepatitis B Virus Pres1 Domain Hijacks Host Trafficking Proteins by Motif Mimicry.
Nat.Chem.Biol., 9, 2013
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4CB8
 | | Structural and mutational analysis reveals that CTNNBL1 binds NLSs in a manner distinct from that of its closest armadillo-relative, karyopherin alpha | | 分子名称: | BETA-CATENIN-LIKE PROTEIN 1, SULFATE ION | | 著者 | Ganesh, K, vanMaldegem, F, Telerman, S.B, Simpson, P, Johnson, C.M, Williams, R.L, Neuberger, M.S, Rada, C. | | 登録日 | 2013-10-10 | | 公開日 | 2013-12-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural and Mutational Analysis Reveals that Ctnnbl1 Binds Nlss in a Manner Distinct from that of its Closest Armadillo-Relative, Karyopherin Alpha
FEBS Lett., 588, 2014
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4CB9
 | | Structure of full-length CTNNBL1 in P43212 space group | | 分子名称: | BETA-CATENIN-LIKE PROTEIN 1 | | 著者 | Ganesh, K, vanMaldegem, F, Telerman, S.B, Simpson, P, Johnson, C.M, Williams, R.L, Neuberger, M.S, Rada, C. | | 登録日 | 2013-10-10 | | 公開日 | 2013-12-04 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural and Mutational Analysis Reveals that Ctnnbl1 Binds Nlss in a Manner Distinct from that of its Closest Armadillo-Relative, Karyopherin Alpha
FEBS Lett., 588, 2014
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4CBA
 | | Structural of delta 1-76 CTNNBL1 in space group I222 | | 分子名称: | 1,2-ETHANEDIOL, BETA-CATENIN-LIKE PROTEIN 1, SULFATE ION | | 著者 | Ganesh, K, vanMaldegem, F, Telerman, S.B, Simpson, P, Johnson, C.M, Williams, R.L, Neuberger, M.S, Rada, C. | | 登録日 | 2013-10-10 | | 公開日 | 2013-12-04 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural and mutational analysis reveals that CTNNBL1 binds NLSs in a manner distinct from that of its closest armadillo-relative, karyopherin alpha.
Febs Lett., 588, 2014
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6GBU
 | | Crystal structure of the second SH3 domain of FCHSD2 (SH3-2) in complex with the fourth SH3 domain of ITSN1 (SH3d) | | 分子名称: | F-BAR and double SH3 domains protein 2, Intersectin-1 | | 著者 | Almeida-Souza, L, Frank, R, Garcia-Nafria, J, Colussi, A, Gunawardana, N, Johnson, C.M, Yu, M, Howard, G, Andrews, B, Vallis, Y, McMahon, H.T. | | 登録日 | 2018-04-16 | | 公開日 | 2018-06-13 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.44 Å) | | 主引用文献 | A Flat BAR Protein Promotes Actin Polymerization at the Base of Clathrin-Coated Pits.
Cell, 174, 2018
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5NP0
 | | Closed dimer of human ATM (Ataxia telangiectasia mutated) | | 分子名称: | Serine-protein kinase ATM | | 著者 | Baretic, D, Pollard, H.K, Fisher, D.I, Johnson, C.M, Santhanam, B, Truman, C.M, Kouba, T, Fersht, A.R, Phillips, C, Williams, R.L. | | 登録日 | 2017-04-13 | | 公開日 | 2017-05-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | | 主引用文献 | Structures of closed and open conformations of dimeric human ATM.
Sci Adv, 3, 2017
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5NP1
 | | Open protomer of human ATM (Ataxia telangiectasia mutated) | | 分子名称: | Serine-protein kinase ATM | | 著者 | Baretic, D, Pollard, H.K, Fisher, D.I, Johnson, C.M, Santhanam, B, Truman, C.M, Kouba, T, Fersht, A.R, Phillips, C, Williams, R.L. | | 登録日 | 2017-04-13 | | 公開日 | 2017-05-17 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | | 主引用文献 | Structures of closed and open conformations of dimeric human ATM.
Sci Adv, 3, 2017
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1K5R
 | | YAP65 WW domain S24-Amino-Ethylsulfanyl-Acetic Acid mutant | | 分子名称: | 65 KDA YES-ASSOCIATED PROTEIN, Fragment of WBP-1 | | 著者 | Ferguson, N, Pires, J.R, Toepert, F, Johnson, C.M, Pan, Y.P, Volkmer-Engert, R, Schneider-Mergener, J, Daggett, V, Oschkinat, H, Fersht, A.R. | | 登録日 | 2001-10-12 | | 公開日 | 2001-11-02 | | 最終更新日 | 2023-11-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Using flexible loop mimetics to extend phi-value analysis to secondary structure interactions.
Proc.Natl.Acad.Sci.USA, 98, 2001
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1KCQ
 | | Human Gelsolin Domain 2 with a Cd2+ bound | | 分子名称: | CADMIUM ION, GELSOLIN | | 著者 | Kazmirski, S.L, Isaacson, R.L, An, C, Buckle, A, Johnson, C.M, Daggett, V, Fersht, A.R. | | 登録日 | 2001-11-09 | | 公開日 | 2002-01-04 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Loss of a metal-binding site in gelsolin leads to familial amyloidosis-Finnish type.
Nat.Struct.Biol., 9, 2002
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2WQG
 | | SAP domain from Tho1: L31W (fluorophore) mutant | | 分子名称: | PROTEIN THO1 | | 著者 | Dodson, C.A, Ferguson, N, Rutherford, T.J, Johnson, C.M, Fersht, A.R. | | 登録日 | 2009-08-21 | | 公開日 | 2010-02-16 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Engineering a Two-Helix Bundle Protein for Folding Studies.
Protein Eng.Des.Sel., 23, 2010
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2XB1
 | | Crystal structure of the human Pygo2 PHD finger in complex with the B9L HD1 domain | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, PYGOPUS HOMOLOG 2, ... | | 著者 | Miller, T.C, Rutherford, T.J, Johnson, C.M, Fiedler, M, Bienz, M. | | 登録日 | 2010-04-01 | | 公開日 | 2010-07-28 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Allosteric Remodeling of the Histone H3 Binding Pocket in the Pygo2 Phd Finger Triggered by its Binding to the B9L/Bcl9 Co-Factor.
J.Mol.Biol., 401, 2010
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2WUS
 | | Bacterial actin MreB assembles in complex with cell shape protein RodZ | | 分子名称: | PUTATIVE UNCHARACTERIZED PROTEIN, ROD SHAPE-DETERMINING PROTEIN MREB | | 著者 | van den Ent, F, Johnson, C.M, Persons, L, deBoer, P, Lowe, J. | | 登録日 | 2009-10-08 | | 公開日 | 2010-06-30 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Bacterial Actin Mreb Assembles in Complex with Cell Shape Protein Rodz.
Embo J., 29, 2010
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