2AZM
| Crystal structure of the MDC1 brct repeat in complex with the histone tail of gamma-H2AX | 分子名称: | GAMMA-H2AX HISTONE, Mediator of DNA damage checkpoint protein 1 | 著者 | Clapperton, J.A, Stucki, M, Mohammad, D, Yaffe, M.B, Jackson, S.P, Smerdon, S.J. | 登録日 | 2005-09-12 | 公開日 | 2006-01-31 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | 主引用文献 | MDC1 Directly Binds Phosphorylated Histone H2AX to Regulate Cellular Responses to DNA Double-Strand Breaks Cell(Cambridge,Mass.), 123, 2005
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1Z56
| Co-Crystal Structure of Lif1p-Lig4p | 分子名称: | DNA ligase IV, Ligase interacting factor 1 | 著者 | Dore, A.S, Furnham, N, Davies, O.R, Sibanda, B.L, Chirgadze, D.Y, Jackson, S.P, Pellegrini, L, Blundell, T.L. | 登録日 | 2005-03-17 | 公開日 | 2006-01-31 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.92 Å) | 主引用文献 | Structure of an Xrcc4-DNA ligase IV yeast ortholog complex reveals a novel BRCT interaction mode. DNA REPAIR, 5, 2006
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3I0M
| Structure of the S. pombe Nbs1 FHA/BRCT-repeat domain | 分子名称: | DNA repair and telomere maintenance protein nbs1, GLYCEROL | 著者 | Clapperton, J.A, Lloyd, J, Chapman, J.R, Jackson, S.P, Smerdon, S.J. | 登録日 | 2009-06-25 | 公開日 | 2009-10-13 | 最終更新日 | 2012-05-02 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage Cell(Cambridge,Mass.), 139, 2009
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3I0N
| Structure of the S. pombe Nbs1 FHA/BRCT-repeat domain | 分子名称: | DNA repair and telomere maintenance protein nbs1, GLYCEROL | 著者 | Clapperton, J.A, Lloyd, J, Chapman, J.R, Jackson, S.P, Smerdon, S.J. | 登録日 | 2009-06-25 | 公開日 | 2009-10-13 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage Cell(Cambridge,Mass.), 139, 2009
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1IK9
| CRYSTAL STRUCTURE OF A XRCC4-DNA LIGASE IV COMPLEX | 分子名称: | DNA LIGASE IV, DNA REPAIR PROTEIN XRCC4 | 著者 | Sibanda, B.L, Critchlow, S.E, Begun, J, Pei, X.Y, Jackson, S.P, Blundell, T.L, Pellegrini, L. | 登録日 | 2001-05-03 | 公開日 | 2001-11-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of an Xrcc4-DNA ligase IV complex. Nat.Struct.Biol., 8, 2001
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1GXC
| FHA domain from human Chk2 kinase in complex with a synthetic phosphopeptide | 分子名称: | SERINE/THREONINE-PROTEIN KINASE CHK2, SYNTHETIC PHOSPHOPEPTIDE | 著者 | Li, J, Williams, B.L, Haire, L.F, Goldberg, M, Wilker, E, Durocher, D, Yaffe, M.B, Jackson, S.P, Smerdon, S.J. | 登録日 | 2002-04-02 | 公開日 | 2002-06-13 | 最終更新日 | 2016-12-21 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural and Functional Versatility of the Fha Domain in DNA-Damage Signaling by the Tumor Suppressor Kinase Chk2 Mol.Cell, 9, 2002
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2QM4
| Crystal structure of human XLF/Cernunnos, a non-homologous end-joining factor | 分子名称: | Non-homologous end-joining factor 1 | 著者 | Li, Y, Chirgadze, D.Y, Sibanda, B.L, Bolanos-Garcia, V.M, Davies, O.R, Blundell, T.L. | 登録日 | 2007-07-14 | 公開日 | 2007-12-11 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ. Embo J., 27, 2008
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1M2K
| Sir2 homologue F159A mutant-ADP ribose complex | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, Silent Information Regulator 2, ZINC ION | 著者 | Chang, J, Cho, Y. | 登録日 | 2002-06-24 | 公開日 | 2003-04-08 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Structural basis for the NAD-dependent deacetylase mechanism of Sir2 J.BIOL.CHEM., 277, 2002
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1M2G
| Sir2 homologue-ADP ribose complex | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, Silent Information Regulator 2, ZINC ION | 著者 | Chang, J, Cho, Y. | 登録日 | 2002-06-24 | 公開日 | 2003-04-08 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural basis for the NAD-dependent deacetylase mechanism of Sir2 J.BIOL.CHEM., 277, 2002
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1M2J
| Sir2 homologue H80N mutant-ADP ribose complex | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, Silent Information Regulator 2, ZINC ION | 著者 | Chang, J, Cho, Y. | 登録日 | 2002-06-24 | 公開日 | 2003-04-08 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural basis for the NAD-dependent deacetylase mechanism of Sir2 J.BIOL.CHEM., 277, 2002
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1M2H
| Sir2 homologue S24A mutant-ADP ribose complex | 分子名称: | ADENOSINE-5-DIPHOSPHORIBOSE, Silent Information Regulator 2, ZINC ION | 著者 | Chang, J, Cho, Y. | 登録日 | 2002-06-24 | 公開日 | 2003-04-08 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural basis for the NAD-dependent deacetylase mechanism of Sir2 J.BIOL.CHEM., 277, 2002
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1M2N
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1D3U
| TATA-BINDING PROTEIN/TRANSCRIPTION FACTOR (II)B/BRE+TATA-BOX COMPLEX FROM PYROCOCCUS WOESEI | 分子名称: | DNA 23-MER: BRE+TATA-BOX, DNA 24-MER: BRE+TATA-BOX, TATA-BINDING PROTEIN, ... | 著者 | Littlefield, O, Korkhin, Y, Sigler, P.B. | 登録日 | 1999-10-01 | 公開日 | 1999-11-15 | 最終更新日 | 2021-11-03 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | The structural basis for the oriented assembly of a TBP/TFB/promoter complex. Proc.Natl.Acad.Sci.USA, 96, 1999
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6HXT
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6HXY
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6HXV
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3WTD
| Structure of PAXX | 分子名称: | Uncharacterized protein C9orf142 | 著者 | Ochi, T, Blundell, T.L. | 登録日 | 2014-04-09 | 公開日 | 2015-01-21 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair. Science, 347, 2015
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3WTF
| Structure of PAXX | 分子名称: | Uncharacterized protein C9orf142 | 著者 | Ochi, T, Blundell, T.L. | 登録日 | 2014-04-09 | 公開日 | 2015-01-21 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.451 Å) | 主引用文献 | DNA repair. PAXX, a paralog of XRCC4 and XLF, interacts with Ku to promote DNA double-strand break repair. Science, 347, 2015
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2N5N
| Structure of an N-terminal domain of CHD4 | 分子名称: | Chromodomain-helicase-DNA-binding protein 4 | 著者 | Silva, A.P.G, Mackay, J.P. | 登録日 | 2015-07-22 | 公開日 | 2015-11-18 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | The N-terminal Region of Chromodomain Helicase DNA-binding Protein 4 (CHD4) Is Essential for Activity and Contains a High Mobility Group (HMG) Box-like-domain That Can Bind Poly(ADP-ribose). J.Biol.Chem., 291, 2016
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1PCZ
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4FBW
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4FBQ
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4FCX
| S.pombe Mre11 apoenzym | 分子名称: | DNA repair protein rad32, MANGANESE (II) ION | 著者 | Schiller, C.B, Lammens, K, Hopfner, K.P. | 登録日 | 2012-05-25 | 公開日 | 2012-06-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure of Mre11-Nbs1 complex yields insights into ataxia-telangiectasia-like disease mutations and DNA damage signaling. Nat.Struct.Mol.Biol., 19, 2012
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4FBK
| Crystal structure of a covalently fused Nbs1-Mre11 complex with one manganese ion per active site | 分子名称: | DNA repair and telomere maintenance protein nbs1,DNA repair protein rad32 CHIMERIC PROTEIN, MANGANESE (II) ION, SULFATE ION | 著者 | Schiller, C.B, Lammens, K, Hopfner, K.P. | 登録日 | 2012-05-23 | 公開日 | 2012-06-20 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.379 Å) | 主引用文献 | Structure of Mre11-Nbs1 complex yields insights into ataxia-telangiectasia-like disease mutations and DNA damage signaling. Nat.Struct.Mol.Biol., 19, 2012
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4D2H
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