3DWZ
| Meropenem Covalent Adduct with TB Beta-lactamase | 分子名称: | (2S,3R,4S)-4-{[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, Beta-lactamase, PHOSPHATE ION | 著者 | Tremblay, L.W, Hugonnet, J.E, Blanchard, J.S. | 登録日 | 2008-07-23 | 公開日 | 2009-03-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Meropenem-clavulanate is effective against extensively drug-resistant Mycobacterium tuberculosis Science, 323, 2009
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3CG5
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3ZGP
| NMR structure of the catalytic domain from E. faecium L,D- transpeptidase acylated by ertapenem | 分子名称: | (4R,5S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-4-methyl-4,5-dihydro-1H-pyrrole-2-carboxylic acid, ERFK/YBIS/YCFS/YNHG | 著者 | Lecoq, L, Triboulet, S, Dubee, V, Bougault, C, Hugonnet, J.E, Arthur, M, Simorre, J.P. | 登録日 | 2012-12-18 | 公開日 | 2013-04-24 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | The Structure of Enterococcus Faecium L,D---Transpeptidase Acylated by Ertapenem Provides Insight Into the Inactivation Mechanism. Acs Chem.Biol., 8, 2013
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3ZG4
| NMR structure of the catalytic domain from E. faecium L,D- transpeptidase | 分子名称: | ERFK/YBIS/YCFS/YNHG | 著者 | Lecoq, L, Dubee, V, Triboulet, S, Bougault, C, Hugonnet, J.E, Arthur, M, Simorre, J.P. | 登録日 | 2012-12-14 | 公開日 | 2013-04-24 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | The Structure of Enterococcus Faecium L,D---Transpeptidase Acylated by Ertapenem Provides Insight Into the Inactivation Mechanism. Acs Chem.Biol., 8, 2013
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6FJ1
| Structure of the Ldtfm-avibactam carbamoyl enzyme | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, 3,6,9,12,15-PENTAOXAHEPTADECANE, CHLORIDE ION, ... | 著者 | Li de la Sierra Gallay, I, Iannazzo, L, Compain, F, Fonvielle, M, van Tilbeurgh, H, Edoo, Z, Arthur, M, Etheve-Quelquejeu, M, Hugonnet, J. | 登録日 | 2018-01-19 | 公開日 | 2019-01-30 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Synthesis of Avibactam Derivatives and Activity on beta-Lactamases and Peptidoglycan Biosynthesis Enzymes of Mycobacteria. Chemistry, 24, 2018
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1ZAT
| Crystal Structure of an Enterococcus faecium peptidoglycan binding protein at 2.4 A resolution | 分子名称: | L,D-transpeptidase, SULFATE ION, ZINC ION | 著者 | Biarrotte-Sorin, S, Hugonnet, J.-E, Mainardi, J.-L, Gutmann, L, Rice, L, Arthur, M, Mayer, C. | 登録日 | 2005-04-07 | 公開日 | 2006-03-28 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structure of a Novel beta-Lactam-insensitive Peptidoglycan Transpeptidase. J.Mol.Biol., 359, 2006
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6NTZ
| Crystal structure of E. coli PBP5-meropenem | 分子名称: | (2S,3R,4S)-4-{[(3S,5R)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, D-alanyl-D-alanine carboxypeptidase | 著者 | Caveney, N.A, Strynadka, N.C.J, Caballero, G, Worrall, L.J. | 登録日 | 2019-01-30 | 公開日 | 2019-03-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural insight into YcbB-mediated beta-lactam resistance in Escherichia coli. Nat Commun, 10, 2019
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6NTW
| Crystal structure of E. coli YcbB | 分子名称: | (2S,3R,4S)-4-{[(3S,5R)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl}-2-[(2S,3R)-3-hydroxy-1-oxobutan-2-yl]-3-methyl-3,4-dihydro-2H-pyrrole-5-carboxylic acid, Probable L,D-transpeptidase YcbB, SULFATE ION | 著者 | Caveney, N.A, Strynadka, N.C.J, Caballero, G, Worrall, L.J. | 登録日 | 2019-01-30 | 公開日 | 2019-03-20 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (2.76 Å) | 主引用文献 | Structural insight into YcbB-mediated beta-lactam resistance in Escherichia coli. Nat Commun, 10, 2019
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4YFM
| Class A beta-lactamase from Mycobacterium abscessus | 分子名称: | ACETATE ION, Beta-lactamase, GLYCEROL | 著者 | Soroka, D, Li de la Sierra-Gallay, I, Dubee, V, van Tilbeurgh, H, Arthur, M. | 登録日 | 2015-02-25 | 公開日 | 2015-07-22 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Hydrolysis of Clavulanate by Mycobacterium tuberculosis beta-Lactamase BlaC Harboring a Canonical SDN Motif. Antimicrob.Agents Chemother., 59, 2015
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