5LJJ
 
 | | Crystal structure of human Mps1 (TTK) in complex with Reversine | | 分子名称: | 1,2-ETHANEDIOL, Dual specificity protein kinase TTK, N~6~-cyclohexyl-N~2~-(4-morpholin-4-ylphenyl)-9H-purine-2,6-diamine | | 著者 | Hiruma, Y, Joosten, R.P, Perrakis, A. | | 登録日 | 2016-07-18 | | 公開日 | 2016-10-12 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Structural basis of reversine selectivity in inhibiting Mps1 more potently than aurora B kinase.
Proteins, 84, 2016
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2M56
 | | The structure of the complex of cytochrome P450cam and its electron donor putidaredoxin determined by paramagnetic NMR spectroscopy | | 分子名称: | CAMPHOR, Camphor 5-monooxygenase, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Hiruma, Y, Hass, M.A.S, Ubbink, M. | | 登録日 | 2013-02-14 | | 公開日 | 2013-08-21 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | The structure of the cytochrome p450cam-putidaredoxin complex determined by paramagnetic NMR spectroscopy and crystallography.
J.Mol.Biol., 425, 2013
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5MRB
 | | Crystal structure of human Mps1 (TTK) in complex with Cpd-5 | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, Dual specificity protein kinase TTK, ... | | 著者 | Hiruma, Y, Joosten, R.P, Perrakis, A. | | 登録日 | 2016-12-22 | | 公開日 | 2017-07-26 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Understanding inhibitor resistance in Mps1 kinase through novel biophysical assays and structures.
J. Biol. Chem., 292, 2017
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5O91
 | | Crystal structure of human Mps1 (TTK) C604W mutant in complex with Cpd-5 | | 分子名称: | 1,2-ETHANEDIOL, Dual specificity protein kinase TTK, ~{N}-(2,6-diethylphenyl)-8-[[2-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino]-1-methyl-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide | | 著者 | Hiruma, Y, Joosten, R.P, Perrakis, A. | | 登録日 | 2017-06-15 | | 公開日 | 2017-07-26 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Understanding inhibitor resistance in Mps1 kinase through novel biophysical assays and structures.
J. Biol. Chem., 292, 2017
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5NTT
 | | Crystal structure of human Mps1 (TTK) C604Y mutant in complex with NMS-P715 | | 分子名称: | 1,2-ETHANEDIOL, Dual specificity protein kinase TTK, N-(2,6-DIETHYLPHENYL)-1-METHYL-8-({4-[(1-METHYLPIPERIDIN-4-YL)CARBAMOYL]-2-(TRIFLUOROMETHOXY)PHENYL}AMINO)-4,5-DIHYDRO-1H-PYRAZOLO[4,3-H]QUINAZOLINE-3-CARBOXAMIDE | | 著者 | Hiruma, Y, Joosten, R.P, Perrakis, A. | | 登録日 | 2017-04-28 | | 公開日 | 2017-07-26 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Understanding inhibitor resistance in Mps1 kinase through novel biophysical assays and structures.
J. Biol. Chem., 292, 2017
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3W9C
 | | Crystal structure of the electron transfer complex of cytochrome p450cam with putidaredoxin | | 分子名称: | Camphor 5-monooxygenase, FE2/S2 (INORGANIC) CLUSTER, GLYCEROL, ... | | 著者 | Kikui, Y, Hiruma, Y, Hass, M.A, Koteishi, H, Ubbink, M, Nojiri, M. | | 登録日 | 2013-04-03 | | 公開日 | 2013-08-21 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | The structure of the cytochrome p450cam-putidaredoxin complex determined by paramagnetic NMR spectroscopy and crystallography.
J.Mol.Biol., 425, 2013
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6GVJ
 | | Human Mps1 kinase domain with ordered activation loop | | 分子名称: | CHLORIDE ION, Dual specificity protein kinase TTK, GLYCEROL | | 著者 | Roorda, J.C, Hiruma, Y, Joosten, R.P, Perrakis, A. | | 登録日 | 2018-06-21 | | 公開日 | 2019-01-09 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | A crystal structure of the human protein kinase Mps1 reveals an ordered conformation of the activation loop.
Proteins, 87, 2019
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5GXG
 | | High-resolution crystal structure of the electron transfer complex of cytochrome p450cam with putidaredoxin | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, Camphor 5-monooxygenase, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Kikui, Y, Hiruma, Y, Ubbink, M, Nojiri, M. | | 登録日 | 2016-09-17 | | 公開日 | 2017-01-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Identification of productive and futile encounters in an electron transfer protein complex
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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2YR5
 | | Crystal structure of L-phenylalanine oxidase from Psuedomonas sp.P501 | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, Pro-enzyme of L-phenylalanine oxidase, ... | | 著者 | Ida, K, Kurabayashi, M, Suguro, M, Hikima, T, Yamamoto, M, Suzuki, H. | | 登録日 | 2007-04-02 | | 公開日 | 2008-04-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | Structural basis of proteolytic activation of L-phenylalanine oxidase from Pseudomonas sp. P-501.
J.Biol.Chem., 283, 2008
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2YR4
 | | Crystal structure of L-phenylalanine oxiase from Psuedomonas sp. P-501 | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, Pro-enzyme of L-phenylalanine oxidase, SULFATE ION | | 著者 | Ida, K, Kurabayashi, M, Suguro, M, Suzuki, H. | | 登録日 | 2007-04-02 | | 公開日 | 2008-04-15 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural basis of proteolytic activation of L-phenylalanine oxidase from Pseudomonas sp. P-501.
J.Biol.Chem., 283, 2008
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2YR6
 | | Crystal structure of L-phenylalanine oxidase from Psuedomonas sp.P501 | | 分子名称: | 2-AMINOBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | | 著者 | Ida, K, Kurabayashi, M, Suguro, M, Suzuki, H. | | 登録日 | 2007-04-02 | | 公開日 | 2008-04-15 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Structural basis of proteolytic activation of L-phenylalanine oxidase from Pseudomonas sp. P-501.
J.Biol.Chem., 283, 2008
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